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Email: pupu0212@yahoo.com.tw
Phone: 886-2-33664100
Office: 漁業科學館R307B
Address: 台北市羅斯福路四段一號
No. 1, Sec. 4, Roosevelt Rd., Taipei, 10617, Taiwan
專長
胚胎發育學
分子生物學
遺傳學
馬魚基因轉殖
研究興趣
1.運用斑馬魚為研究對象,透過分生技術,探討胚胎發育時之基因調控。
a.探討時期及組織專一表現之肌肉調控因子myf-5其內含子(intron)所扮演之負向調控機制。
b.晚期胚胎顱顏部肌肉與軟骨發育之基因調控。
2.以基因轉殖方式改變魚體之體色。
學歷
1989-1992 桃園縣立龍潭國中
1992-1995 桃園縣立武陵高中
1996-2000 私立輔仁大學生物系
2000-2002 國立台灣大學漁業科學研究所碩士班
2002-2006 國立台灣大學分子與細胞生物學研究所博士班
經歷
1996-1997 輔大生物 活動股長
1997 輔中生物營 隊輔
1997-1998 輔大生物系 系學會會長
1997-1998 輔仁大學理代會 副主席
1997 洲子灣兒童生物營 執行長
1998 泰山國小親子生物營 執行長
1999-2000 輔大生物 活動股長
2000-2001 輔大生物 班代
2000 輔大生物 畢業生代表
2000 獲國科會暑期生傑出研究獎
2000 順利甄試上台大漁科所碩士班
2000-2001 台大漁科所碩士班 班代
2002 獲推薦台大斐陶斐榮譽會員
2002 台大漁科所碩士班畢業
2002 獲台大理學院院長獎
2002 順利考上台大分細所博士班
2005 第十三屆 細胞及分子生物新知研討會 壁報論文獎
2006 台大分細所畢業海報比賽 博士班第一名
2006 台大分細所博士班畢業
2006 獲台大生科學學院院長獎
個人著作
期刊論文
Chen YH, Lee HC, Liu CF, Lin CY and Tsai HJ. Novel regulatory sequence -82/-62 functions as a key element to drive the somite-specificity of zebrafish myf-5. Dev. Dyn. 2003, 228, 41-50.
Lin CY, Chen YH, Lee HC and Tsai HJ. Novel cis-element in intron 1 represses somite expression of zebrafish myf-5. Gene. 2004, 334, 63-72.
Sun CK, Chu SW, Chen SY, Tsai TH, Liu TM, Lin CY and Tsai HJ. Higher harmonic generation microscopy for developmental biology. J Struct Biol. 2004, 147, 19-30.
Lee HC, Huang HY, Lin CY, Chen YH and Tsai HJ. Foxd3 mediates zebrafish myf5 expression during early somitogenesis. Dev Biol. 2006, 290, 359-72.
Lin CY, Yung RF, Lee HC, Chen WT, Chen YH and Tsai HJ. Myogenic regulatory factors Myf5 and Myod function distinctly during craniofacial myogenesis of zebrafish. Dev Biol. 2006, 299, 594-608.
Tsai TH, Lin CY, Tsai HJ, Chen SY, Tai SP, Lin KH and Sun CK. Biomolecular imaging based on far-red fluorescent protein with a high two-photon excitation action cross section. Opt Lett. 2006, 31, 930-932.
Chen SY, Hsieh CS, Chu SW, Lin CY, Ko CY, Chen YC, Tsai Hj, Hu CH and Sun CK. Noninvasive harmonics optical microscopy for long-term observation of embryonic nervous system development in vivo. J Biomed Opt. 2006, 11, 054022.
研討會論文
國際性研討會
Lin CY, Chen YH, Liu CF and Tsai HJ. A repressor motif within the first intron required for somite-specific expression of zebrafish myf-5 gene. Postgraduate Conference on Marine Biology and Biotechnology, June. 6-8. 2001. Hongkong. (大會補助)
Lin CY, Chen YH, Lee HC and Tsai HJ. An Intron Segment Represses the Somite-specific Expression of Zebrafish (Danio rerio) myf-5 Gene. Society for Development Biology 62nd Annual Meeting. July 30-August 3. 2003. Marriott Copley Place, Boston, MA. (傑出人才發展基金會全額補助)
Lin CY, Lee HC, Yung RF and Tsai HJ. Novel Function of Myogenic Regulatory Factor Myf5 in Pharyngeal Cartilage Development of Zebrafish. 4th European Zebrafish Genetic and Development Meeting. July. 13-16. 2005. Dresden, Germany. (教育部補助)
Lee HC, Lin CY, Yung RF, Lo FY and Tsai HJ. Myogenic Regulatory Factor Myf5 Functions in Gastrulation and Plays a Role in the Development of Pharyngeal Cartilage, Cranial Neural Crest, and Hindbrain of Zebrafish. Society For Developmental Biology 65th Annual Meeting. Jun. 17-21. 2006. University of Michicgan, Ann Arbor, USA.
Lin CY, Yung RF, Lee HC, Chen WT, Chen YH and Tsai HJ. Myogenic Regulatory Factor Myf5 and Myod Function Distinctly during Craniofacial Myogenesis of Zebrafish. Society For Developmental Biology 65th Annual Meeting. Jun. 17-21. 2006. University of Michicgan, Ann Arbor, USA.
地區性研討會
Lin CY, Chen YH, Lee HC and Tsai HJ. An intron segment represses the somite-specific expression of zebrafish myf-5 gene. Tenth Symposium on Recent Advances in Cellular and Molecular Biology, Jan. 25-28. 2002. Kenting, Taiwan.
Lee HC, Chen YH, Lin CY and Tsai HJ. Dual functions of a novel -82/-63 motif of zebrafish myf-5: enhancing the somite-specific expression and repressing the non-specific expression during the early embryogenesis. Tenth Symposium on Recent Advances in Cellular and Molecular Biology, Jan. 25-28. 2002. Kenting, Taiwan.
Lin CY, Chen YH, Lee HC and Tsai HJ. An intron segment represses the somite-specific expression of zebrafish myf-5 gene. The Seventeenth Joint Annual Conference of Biomedical Science, Mar. 23-24. 2002. Taipei, Taiwan.
Lee HC, Chen YH, Lin CY and Tsai HJ. Dual functions of a novel -82/-63 motif of zebrafish myf-5: enhancing the somite-specific expression and repressing the non-specific expression during the early embryogenesis. The Seventeenth Joint Annual Conference of Biomedical Science, Mar. 23-24. 2002. Taipei, Taiwan.
Lee HC, Huang HY, Lin CY, Chen YH and Tsai HJ. Direct binding of FoxD3 to -82/-62 cis-element may mediate the activation of zebrafish myf5 expression during early somitogenesis. 13th Symposium on recent advances in cellular and molecular biology. Feb. 26-28. 2005. Kenting, Taiwan.
Lin, C.Y., Lee, H.C, Yung, R.F. and Tsai H.J. Novel function of myogenic regulatory factor Myf5 in pharyngeal cartilage development of zebrafish. 13th Symposium on recent advances in cellular and molecular biology. Feb 26-28. 2005. Kenting, Taiwan.
Lee, H.C., Huang H.Y., Lin, C.Y., Chen, Y.H. and Tsai H.J. Foxd3 mediates zebrafish myf5 expression during early somitogenesis. The Seventeenth Joint Annual Conference of Biomedical Science. Mar 18-19. 2006. Taipei, Taiwan.