Publications (2011-
2020) |
- Chen SY, Chiu LY, Maa MC, Wang JS, Chien CL,
Lin WW. zVAD-induced autophagic cell death requires c-Src-dependent ERK
and JNK activation and reactive oxygen species generation. Autophagy. 2011; 7(2):217-28.
- Tseng KW, Peng ML, Wen YC, Liu KJ and Chien CL*. Neuronal degeneration in autonomic nervous system of dystonia musculorum mice. J Biomed Sci. 2011; 18:9.
- Huang HP, Chen PH, Hwu WL, Chuang CY, Chien YH, Stone L, Chien CL,
Li LT, Chiang SC, Chen HF, Ho HN, Chen CH, Kuo HC*. Human Pompe disease
induced pluripotent stem cells for pathogenesis modeling, drug testing
and disease marker identification. Hum Mol Genet. 2011; 20(24):4851-64.
- Lee WC, Chen YY, Kan D, Chien CL*. A neuronal death model: Overexpression of neuronal intermediate filament protein peripherin in PC12 cells. J Biomed Sci. 2012; 19:8. doi:10.1186/1423-0127-19-8.
- Lee WC, Kan D, Chen YY, Han SK, Lu KS, Chien CL*.
Suppression of extensive neurofilament phosphorylation rescues
α-internexin/peripherin-overexpressing PC12 cells from neuronal cell
death. PLoS One. 2012; 7(8):e43883. doi:10.1371.
- Chen YT, Tsai MS, Yang TL, Ku AT, Huang KH, Huang CY,
Chou FJ, Fan HH, Hong JB, Yen ST, Wang WL, Lin CC, Hsu YC, Su KY, Su
IC, Jang CW, Behringer RR, Favaro R, Nicolis SK, Chien CL, Lin SW*, Yu IS*. R26R-GR: A cre-activable dual fluorescent protein reporter mouse. PLoS One. 2012; 7(9):e46171.
- Chen YL, Chang MC, Chen CA, Lin HW, Cheng WF*, Chien CL*.
Depletion of regulatory T lymphocytes reverses the imbalance between
pro- and anti-tumor immunities via enhancing antigen-specific T cell
immune responses. PLoS One. 2012; 7:e47190.
- Chen SJ, Tsai JC, Lin CY, Chang CK, Tseng TH, Chien CL*.
Brain-derived neurotrophic factor-transfected and nontransfected
3T3 fibroblasts enhance migratory neuroblasts and functional
restoration in mice with intracerebral hemorrhage . J Neuropathol Exp Neurol. 2012; 71:1123-1136.
- Peng ML, Tsai CY, Chien CL,
Hsiao JCJ, Huang SY, Lee CJ, Lin HY, Wen YC and Tseng, KW*. The
influence of low-powered family LED lighting on eyes in mice
experimental model. Life Science Journal. 2012; 9:477-482.
- Liu CH, and Chien CL*. Molecular cloning and characterization of chicken neuronal intermediate filament protein α-internexin. J Comp Neurol. 2013; 521:2147-64.
- Liu CH, Wang IJ, Wei FD, Chien CL*.Neuronal intermediate filament α - internexin is expressed by neuronal lineages in the developing chicken retina. Exp Eye Res. 2013; 110:18-25.
- Wang NK, Lai CC, Liu CH, Yeh LK, Chou CL, Kong J, Nagasaki T, Tsang S, and Chien CL*.
Origin of fundus hyperautofluorescent (AF) spots, and their role in
retinal degeneration in a mouse model of Goldmann-Favre Syndrome. Dis Model Mech. 2013; 6:1113-22. doi: 10.1242/dmm.012112.
- Hou PS, Chuang CY, Kao CF, Chou SJ, Stone L, Ho HN, Chien CL*
and Kuo HC*. LHX2 regulates the neural differentiation of human
embryonic stem cells via transcriptional modulation of PAX6 and CER1. Nucleic Acids Res. 2013; 41:7753-7770.
- Shen WC, Liang CJ, Wu VC, Wang SH, Young GH, Lai IR, Chien CL,
Wang SM, Wu KD, Chen YL. Endothelial progenitor cells derived from
Wharton's jelly of the umbilical cord reduces ischemia-induced hind
limb injury in diabetic mice by inducing HIF-1α/IL-8 expression. Stem Cells Dev. 2013; 22:1408-1418.
- Chen YL, Cheng WF, Chang MC, Lin HW, Huang CT, Chien CL* and Chen CA*. Interferon-gamma in ascites could be a predictive biomarker of outcome in ovarian carcinoma. Gynecol Oncol. 2013; 131:63-68.
- Peng ML, Lee CJ, Chien CL,
Liu CL, Tsai CY, Wen YC, Tseng KW*. Protective effects of (-)-epigallocatechin
gallate on blue light-induced damage in retinoblastoma Y79 cells
by activating estrogen receptor pathway. Life Science Journal,
2013; 10: 192-198.
- Chen HF, Jan PS, Kuo HC, Wu FC, Lan CW, Huang MC, Chien CL,
Ho HN*. Granulosa cells and retinoic acid co-treatment enrich potential
germ cells from manually selected Oct4-EGFP expressing human embryonic
stem cells. Reprod Biomed Online. 2014; 05:009. doi: 10.1016/j.rbmo.
- Hong JH, Lee WC, Hsu YM, Liang HJ, Wan CH, Chien CL*,
Lin CY*. Characterization of the biochemical effects of naphthalene on
the mouse respiratory system using NMR-based metabolomics. J Appl Toxicol. 2014; 34(12):1379-1388
- Hou PS, Huang WC, Chiang W, Lin WC, Chien CL*. Impaired neural differentiation potency by retinoic acid receptor-α pathway defect in induced puripotent stem cells. Cell Reprogram. 2014;16:467-476. doi: 10.1089/cell.2014.0029.
- Hong JB, Chou FJ, Ku Amy T., Fan HH, Lee TL, Huang YH, Yang TL , Su IC, Yu IS, Lin SW, Chien CL,
Ho HN, Chen YT*. A nucleolus-predominant piggybac transposase, NP-mPB,
Mediates elevated transposition efficiency in mammalian cells. PLoS One. 2014; 9(2):e89396
- Chao CC, Kan D, Lu KS, Chien CL*. The role of microRNA-30c in the self-renewal and differentiation of C6 glioma cells. Stem Cell Res. 2015; 14(2):211-23. doi: 10.1016/j.scr.2015.01.008.
- Li YC, Chen SJ and Chien CL*. Erythropoietin produced by genetic-modified NIH/3T3 fibroblasts enhances the survival of degenerating neurons. Brain Behav. 2015; 5(8) (Cover), doi:10.1002/brb3.356.
- Chao CC, Kan D, Lo TH, Lu KS, Chien CL*. Induction of neural differentiation in rat c6 glioma cells with taxol. Brain Behav. 2015; 5(12) (Cover), doi: 10.1002/brb3.414
- Liao ML, Peng WH, Kan D, Chien CL*. Developmental Pattern of the neuronal intermediated filament inaa in the zebrafish retina. J Comp Neurol. 2016;
524(18):3810-3826. doi:10.1002/cne.24033.
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Lee WD, Wang KC, Tsai YF, Chou PC, Tsai LK, Chien CL*.
Subarachnoid Hemorrhage Promotes Proliferation, Differentiation,
and Migration of Neural Stem Cells via BDNF Upregulation.
PLoS One.
2016 Nov 10;11(11) : e0165460.
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Numpaisal PO, Rothrauff BB, Gottardi R, Chien CL,
Tuan RS*.
Rapidly dissociated autologous meniscus tissue enhances meniscus
healing: An in vitro study.
Connect Tissue Res.
2017;58(3-4):355-365.
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Pu CM, Liu CW, Liang CJ, Yen YH, Chen SH, Jiang-Shieh YF, Chien
CL, Chen YC, Chen YL*.
Adipose-Derived Stem Cells Protect Skin Flaps against
Ischemia/Reperfusion Injury via IL-6 Expression.
J Invest Dermatol.
2017 Jun;137(6):1353-1362.
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Hsieh MH, Chen YT, Chen YT, Lee YH, Lu J, Chien CL,
Chen HF, Ho HN, Yu CJ, Wang ZQ, Teng SC*.
PARP1 controls KLF4-mediated telomerase expression in stem cells
and cancer cells.
Nucleic Acids Res.
2017 Oct 13;45(18):10492-10503.
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Wong CW, Chen YT, Chien CL, Yu TY, Rwei SP, Hsu
SH*. A simple and efficient feeder-free culture system to
up-scale iPSCs on polymeric material surface for use in 3D
bioprinting.
Mater Sci Eng C Mater Biol Appl.
2018 Jan 1;82:69-79.
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Hsin WC, Chang CH, Chang CY, Peng WH, Chien CL,
Chang MF, Chang SC*. Nucleocapsid protein-dependent assembly of
the RNA packaging signal of Middle East respiratory syndrome
coronavirus. J
Biomed Sci. 2018; 25(1):47.
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Liao ML, Peng WH, Kan D, Chien CL*.
Distribution patterns of the zebrafish neuronal intermediate
filaments inaa and inab. J
Neuro Res. 2018; 00:1–13. doi: 10.1002/jnr.24347.
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Chou PC, Tsai YC, Chen SJ, Tsai LK*,
Chien CL*.
Intracerebral transplantation of erythropoietin‐producing
fibroblasts facilitates neurogenesis and functional recovery in
an ischemic stroke model. Brain Behav.
2019 ;e01274.doi: 10.1002/brb3.1274
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Wu A*, Kielstein H, Sakurai T, Noel G, Viranta-Kovanen S, Chien
CL, Bernd P. Internationalization of medical
education-building a program to prepare future leaders in
healthcare. Med Sci Educ. 2019;29(2):535–47. (International Collaboration).
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Sun N.-Y.; Chen Y.-L.; Lin H.-W.; Chiang Y.-C.; Chang C.-F.; Tai
Y.-J.; Chen C.-A.; Sun W.-Z.; Chien
CL; Cheng W.-F.
Immune checkpoint Ab enhances the antigen-specific anti-tumor
effects by modulating both dendritic cells and regulatory T
lymphocytes. Cancer
Letters. 2019
vol 444 p20-34.
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Chen Y.-L.; Lin H.-W.; Chien
CL.; Lai
Y.-L.; Sun W.-Z.; Chen C.-A.; Cheng W.-F. BTLA blockade enhances
Cancer therapy by inhibiting IL-6/IL-10-induced CD19high B
lymphocytes. Journal
for ImmunoTherapy of Cancer. 2019
vol 7:1 p313.
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Shih J.-C.; Lin H.-H.; Hsiao A.-C.; Su Y.-T.; Tsai S.; Chien
CL.; Kung
H.-N. Unveiling the role of microRNA-7 in linking TGF-β-Smad-mediated
epithelial-mesenchymal transition with negative regulation of
trophoblast invasion. FASEB Journal. 2019
vol 33:5 p 6281-6295.
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Pu C.-M.; Chen Y.-C.; Chen Y.-C.; Lee T.-L.; Peng Y.-S.; Chen
S.-H.; Yen Y.-H.; Chien
CL;
Hsieh J.-H.; Chen Y.-L. Interleukin-6 from Adipose-Derived Stem
Cells Promotes Tissue Repair by the Increase of Cell
Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated
Skin Flaps. Mediators
of Inflammation. 2019
vol 2019 p 2343867.
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Wu A, Noel G, Wingate R, Kielstein H, Sakurai
T, Viranta-KovanenS,
Chien CL,
Traxler H, Waschke J, Vielmuth F, Gill M, Kitahara S, Kato Y,
Keay K, Olson J, Bernd P. An International Partnership of 12
Anatomy Departments – Improving Global Health through
Internationalization of Medical Education.
Annals of Global Health.
2020; 86(1): 27, 1–14.
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