研究成果
期刊論文 (*通訊作者,**共同第一作者)
A. 失智症與老年流行病學研究
- 長者走路步態與認知功能的雙向關係
- 為長者設計的機器人
Memory Robot Design: A New Perspective from Human Brain Model and Large Language Model
- 老年人血管因子(頸動脈內中膜厚度與踝肱指數)可預測認知功能變化
- 老年人雙眼視網膜神經厚度的不對稱性可用於預測認知衰弱的風險
Interocular retinal asymmetry and cognitive frailty: a prospective cohort study
- 14個族群世代之中風前後認知功能下降的軌跡
Trajectory of Cognitive Decline Before and After Stroke in 14 Population Cohorts
- 蛀牙、齒列不整及牙齒磨耗可預測失智症臨床前期之認知障礙
- 「臺灣老年流行病學研究」
- 咖啡和茶降低阿茲海默氏症及血管型失智症風險依性別及血管共病而不同
Coffee and tea consumption and dementia risk: The role of sex and vascular comorbidities
- 以不對稱的握力預測老年人認知功能障礙
- 嗅覺異常能
- 醫師對生命末期的認定可能會影響病人的善終
- 以眼睛視網膜血管分佈型態預測長者早期之認知功能障礙風險
- 首次探討戶外空氣汙染物、室內空氣品質對於長者認知功能的影響(使用多污染物模型考量汙染物間的共線性)
- 為失智症患者開發之機器人
Yu-Lin Zhao, Han-Pang Huang, Pen-Chi Chiang*, Huai-Te Wang, Jen-Hau Chen, Yen-Ching Chen*.
Journal of the Chinese Society of Mechanical Engineers. 44(4):351-360 (August 2023).
[Engineering, Mechanical 領域排名 97%]
- 社區長者臨床前期憂鬱症狀、睡眠與認知功
能關聯之長期世代研究
Association of subclinical depressive symptoms and sleep with cognition in the community-dwelling older adults.
- 老年人飲食品質的重複測值(分為三種軌跡)與認知功能隨時間變化之關聯研究
- 以手部握力及肌少症預測社區老人兩
年後認知功能障礙風險
Grip strength and sarcopenia predict 2-year cognitive impairment in community-dwelling older adults.
- 首次找出華人長者不同性別特有共病型態及其與認知功能之關聯(考量長者失去 追蹤的影響)
- 主動調查比被動篩檢能找出較多的早期失智症
- 失智症照護者負擔自我評估工具之 系統性回顧
Caregiver burden and dementia: A systematic review of self-report instruments.
- 建立新的“認知衰弱”定義，比傳統定義能更全面的 預測老年人全死因
Jen-Hau Chen, Hua-San Shih, Jennifer Tu, Jeng-Min Chiou, Shu-Hui Chang, Wei-Lie Hsu, Liang-Chuang Lai, Ta-Fu Chen, Yen-Ching Chen*.
Journal of Alzheimer’s Disease 84(4):1795-1809 (December 2021).
[Neuroscience 領域排名 37.3%]
- 以社區為本的世代研究探討代謝徵候群與成功老 化的關聯
Yi-Hsuan Lin, Jeng-Min Chiou, Ta-Fu Chen, Liang-Chuan Lai, Jen-Hau Chen, Yen-Ching Chen*.
PLoS ONE. 16(11): e0260550 (December 2021).
[Multidisciplinary Science 領域排名 23.5%]
- 長期空氣汙染物的暴露與老年人認知功能的關係-前瞻性世代研究
Jen-Hau Chen, Tsung-Yu Kuo, Hwa-Lung Yu, Charlene Wu, Su-Ling Yeh, Jeng-Min Chiou, Ta-Fu Cheng, Yen-Ching Chen*.
Journal of Alzheimer’s Disease. 78(4):1585-1600 (December 2020).
[Neuroscience 領域排名 37.3%] - 老年人慢性腎臟疾病與大腦皮質變薄(神經退化)對於認知功能的影響
Chih-Hao Chen, Ya-Fang Chen, Ping-Huan Tsai, Jeng-Min Chiou, Liang-Chuan Lai, Ta-Fu Chen, Hung Hung, Jen-Hau Chen*, Yen-Ching Chen*.
Journal of Alzheimer's Disease. 76(1):225-236 (June 2020).
[Neuroscience 領域排名 37.3%] - 高齡健康與長照研究中心研議計畫 政策建言書，第三篇高齡醫學研究與轉譯重要性，第三章高齡長者失能/失智之世代研究 (
2019 財團法人國家衛生研究院論壇)
議題委員: 劉景寬、黃宗正、王培寧、白明奇、胡朝榮、徐崇堯、郭乃文、陳人豪、陳正生、許志成、傅中玲、程 藴菁、 賴德仁
- 首次發現眼睛的神經纖維厚度與老年認知功能呈現"非線性"關係
Yao-Lin Liu, Yi-Ting Hsieh, Ta-Fu Chen, Jeng-Min Chiou, Min-Kuang Tsai, Jen-Hau Chen*, Yen-Ching Chen*.
Alzheimer’s & Dementia: Diagnosis, Assessment, and Disease Monitoring. 11: 19-27 (December 2019).
[Clinical Neurology 領域排名18%] - 首度探討老年人飲食品質及蔬菜多樣性與認知功能下降之關係
Yi-Chun Chou, Meei-Shyuan Lee, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen*, Jen-Hau Chen*.
Nutrients. 2019, 11(7), 1666 (July 2019).
[Nutrition & Dietetics 領域排名 15.5%] - 幽門桿菌感染增加失智症臨床前期之認知功能障礙風險
Association between Helicobacter pylori infection and cognitive impairment in the elderly.
Ming-Lun Han, Jen-Hau Chen, Min-Kuang Tsai, Jyh-Ming Liou, Jeng-Min Chiou, Ming-Jang Chiu, Yen-Ching Chen*.
Journal of the Formosan Medical Association. 117(11): 994-1002 (November 2018).
[Medicine, General & Internal 領域排名 21.4%] - 老年人經濟狀態影響生活型態及認知功能變化的關係
The effect of lifestyle on late-life cognitive change under different socioeconomic status.
Pei-Hsuan Weng, Jen-Hau Chen, Jeng-Min Chiou, Yu-Kang Tu, Ta-Fu Chen, Ming-Jang Chiu, Sung-Chun Tang, Shin-Joe Yeh, Yen-Ching Chen*.
PLoS ONE. 13(6): e0197676 (June 2018).
[Multidisciplinary Sciences 領域排名 24.5%]
- 老年人慢性腎臟疾病與大腦皮質變薄(神經退化，失智症臨床前期指標)有關
Effect of kidney dysfunction on cerebral cortical thinning in elderly population.
Chih-Hao Chen, Ya-Fang Chen, Ming-Jang Chiu, Ta-Fu Chen, Ping-Huan Tsai, Jen-Hau Chen, Chung-Jen Yen, Sung-Chun Tang, Shin-Joe Yeh, Yen-Ching Chen*.
Scientific Reports 7, Article number: 2337 (May 2017).
[Multidisciplinary Sciences 領域排名 18.3%] - 首次找出華人特有的傳統飲食型態與失智症臨床前期之認知功能下降有關
Yen-Ching Chen*, Chien-Cheng Jung, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, Meei-Shyuan Lee.
Journal of the American Geriatrics Society 65(6):1159-1167 (June 2017).
[Geriatrics & Gerontology 領域排名 23.6%]
- 華人首次晚發型阿茲海默氏症全基因關聯研究：表現指標找出遺傳指標預測晚發型阿茲海默氏症
Performance metrics for selecting genetic polymorphisms in late-onset Alzheimer's disease.
Yen-Ching Chen*, Chi-Jung Hsiao, Chien-Cheng Jung, Hui-Han Hu, Jen-Hau Chen, Wen-Chung Lee, Jeng-Min Chiou, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Chien-Jen Chen*, Hwai-I Yang*.
Scientific Reports 6, Article number: 36155 (November 2016).
[Multidisciplinary Sciences 領域排名 18.3%] - CHRNA7基因多型性、APOE ε4狀態、吸菸三者之交互作用與失智風險的關係
CHRNA7 polymorphisms and dementia risk: Interactions with apolipoprotein ε4 and cigarette smoking.
Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.
Scientific Reports 6, Article number: 27231 (June 2016).
[Multidisciplinary Sciences 領域排名 18.3%]
- 脂質代謝有關的SAR1B基因與APOE ε4同步檢測，大幅提升晚發型阿茲海默氏症的篩檢靈敏度
Jen-Hau Chen, Ching-Jow Hsieh, Yi-Ling Huang, Yen-Ching Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu.
Journal of the Formosan Medical Association. 115:38-44 (January 2016).
[Medicine, General & Internal 領域排名 21.4%] - 第三部分：失智症研究中的遺傳流行病學研究“失智症及其照護原則”歐陽文貞(主編)
程蘊菁
社團法人台灣老年精神醫學會 台中,台灣. (2015) p.97-101. ISBN: 978-986-90-0401-5 (專書章節)
- 首篇空氣汙染與臨床診斷的阿茲海默氏症及血管型失智症的關聯性研究
Special Invited Article: Association between air pollutants and dementia risk in the elderly.
Yun-Chun Wu, Yuan-Chien Lin, Hwa-Lung Yu, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.
Alzheimer’s & Dementia: Diagnosis, Assessment, and Disease Monitoring 1(2): 220-228 (May 2015).
[Clinical Neurology 領域排名18%]台灣臨床失智症學會 財團法人立夫醫藥研究文教基金會學術獎
台 大公衛焦點新聞 : 空氣中懸浮微粒（PM10）及臭氧恐增加失智症風險 - 老年人宗教信仰與阿茲海默氏症的關聯
Religious affiliation and the risk of dementia in Taiwanese elderly.
Kun-Pei Lin, Yi-Chun Chou, Jen-Hau Chen, Chi-Dan Chen, Sheng-Ying Yang, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.
Archives of Gerontology and Geriatrics 60(3): 501-6 (May-Jun 2015).
[Geriatrics & Gerontology 領域排名 38.5%] - 三種休閒活動、APOE ε4基因型及失智症風險的關聯
Leisure activities, apolipoprotein E e4 status, and the risk of dementia.
Sheng-Ying Yang, Pei-Hsuan Weng, Jen-Hau Chen, Jeng-Min Chiou, Chih-Yin Lew-Ting, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.
Journal of the Formosan Medical Association. 114:1216-1224 (December 2015).
[Medicine, General & Internal 領域排名 21.4%] - 首篇探討老化基因 CISD2與晚發型阿茲海默氏症的關聯
Sequence variants of the aging gene CISD2 and the risk of Alzheimer’s disease.
Ching-Jow Hsieh, Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yiph, Yi-Min Chu, Yen-Ching Chen*.
Journal of the Formosan Medical Association. 114 (7): 627-632 (July 2015).
[Medicine, General & Internal 領域排名 21.4%] - 失
智 症之重點回顧.
梁家欣, 程蘊菁, 陳人豪
內科學誌. 25: 151-157 (July 2014).
- CHRNA7
基因多型性對於阿茲海默氏症患者服用膽鹼酯酶抑制劑的影響
CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer’s disease.
Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.
PLoS ONE 8(12): e84059 (December 2013).
Merck Sharp & Dohme Excellent Thesis Award, Taiwan Geriatrics Society (台灣老年醫學會默沙東優秀論文獎)
- TLR4
基因多型性和晚發型阿茲海默氏症的關聯
Sequence variants of toll-like receptor 4 and late-onset Alzheimer’s disease.
Yen-Ching Chen*, Ping-Keung Yip, Yi-Ling Huang, Yu Sun, Li-Li Wen, Yi-Min Chu, Ta-Fu Chen.PLoS ONE 7 (12): e50771 (December 2012).
- IL-6 基因
多型性降低晚發型阿茲海默氏症的風險
Shih-Yuan Chen, Ta-Fu Chen, Liang-Chuan Lai, Jen-Hau Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.
Journal of Neuroinflammation 9:21 (January 2012).
- NGFR 基因
多型性和晚發型阿茲海默氏症的關聯
Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease.
Hui-Chi Cheng, Yu Sun, Liang-Chuan Lai, Shih-Yuan Chen, Wen-Chung Lee, Jen-Hau Chen, Ta-Fu Chen, Hua-Hsiang Chen, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Wei J. Chen, Yen-Ching Chen*.
Journal of Negative Results in Biomedicine 11:5 (January 2012).
- CLU 基因多
型性和晚發型阿茲海默氏症的關聯
Yen-Ling Lin, Shih-Yuan Chen, Liang-Chuan Lai, Jen-Hau Chen, Shi-Yi-Yang, Yi-Ling Huang, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Wei J. Chen, Yen-Ching Chen*.
European Journal of Epidemiology 27(1):73-75 (January 2012).
- 基
因檢測於老年人阿茲海默氏病的風險預測
程蘊菁, 陳人豪.
健康世界 432: 26-27 (December 2011).
- 血管易感受基因NINJ2 基
因多型性降低晚發型阿茲海默氏症風險
Kun-Pei Lin, Shih-Yuan Chen, Liang-Chuan Lai, Yi-Ling Huang, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Wei J. Chen, Yen-Ching Chen*.
PLoS ONE 6(6): e20573 (June 2011).
Outstanding Master Thesis Award, Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association 2011 Joint Annual Meeting and Symposium (台灣公共衛生年會 2012年聯合年會碩士生論文獎)
- 早年身體質量數指標和失智症的關聯
Body mass index at early age and the risk of dementia.
Yen-Ching Chen, Ta-Fu Chen, Ping-Keung Yip, Chi-Yin Hu, Yi-Min Chu, Jen-Hau Chen.Archives of Gerontology and Geriatrics 50 Suppl 1:S48-52 (February 2010).
- 失智症風險因子
Jen-Hau Chen, Kun-Pei Lin, Yen-Ching Chen*.
Journal of the Formosan Medical Association. 108(10): 754-764 (October 2009).
- 長照住民疑似肺癌的發生與治療
Jen-Hau Chen, Jennifer L. Lamberg, Yen-Ching Chen, Dan K.
Kiely, John H. Page, Carmel J. Person, Susan L. Mitchell.
Journal of the American Geriatrics Society 54(2): 290-295 (February 2006).
Ying-Hao Su, Jeng-Min Chiou, Chengshi Shiu, Jen-Hau Chen*, Yen-Ching Chen*
Journal of the American Medical
Directors Association 10544 (March 2025).
[Geriatrics & Gerontology 領域排名 23.6%]
Jia-Hsun Lo,Han-Pang Huang,* Yen-Ching Chen, Jen-Hau Chen
IEEE Access 13: 28539-28549 (February
2025).
[Computer Science, Information Systems 領域排名 34.6%]
Kai-Jing Yeh**, Meng-Jie Sun**, Shin-Joe Yeh, Sung-Chun Tang, Jeng-Min Chiou, Yen-Ching Chen*, Jen-Hau Chen*
Journal of Alzheimer’s Disease 104(3)
(2025, in press).
[Neuroscience 領域排名 37.3%]
Yung-Sung Lee, Yi-Ting Hsieh, Te-Hsuan Huang, Jeng-Min Chiou, Tao-Chun Peng, Yao-Lin Liu, Jen-Hau Chen*, Yen-Ching Chen*
Alzheimer's & Dementia 21(2):
e14437 (February 2025).
[Clinical Neurology 領域排名 1.7%]
Jessica W. Lo, John D. Crawford, Darren M. Lipnicki, Richard B. Lipton, Mindy J. Katz, Pierre-Marie Preux, Maëlenn Guerchet, Eleonora d’Orsi, Anna Quialheiro, Cassiano Ricardo Rech, Karen Ritchie, Ingmar Skoog, Jenna Najar, Therese Rydberg Sterner, Elena Rolandi, Annalisa Davin, Michele Rossi, Steffi G. Riedel-Heller, Alexander Pabst, Susanne Röhr, Mary Ganguli, Erin Jacobsen, Beth E. Snitz, Kaarin J. Anstey, Allison E. Aiello, Henry Brodaty, Nicole A. Kochan, Yen-Ching Chen, Jen-Hau Chen, Pascual Sanchez-Juan, Teodoro del Ser, Meritxell Valentí, Antonio Lobo, Concepción De-la-Cámara, Elena Lobo, Perminder S. Sachdev
JAMA Network Open 7(10):e2437133
(October 2024).
[Medicine, General & Internal 領域排名 3.5%]
Jung-Tsu Chen, Stephanie Tsai, Min-Huey Chen, Waranuch Pitiphat, Oranart Matangkasombut, Jeng-Min Chiou, Ming-Lun Hang, Jen-Hau Chen*, Yen-Ching Chen*
Journal of Dentistry 7:105088 (August
2024).
[Dentistry, Oral Surgery & Medicine 領域排名 4.1%]
Pei-Iun Hsieh, Te-Hsuan Huang, Jeng-Min Chiou, Jen-Hau Chen*, Yen-Ching Chen*
Epidemiology and Health e2024057 (June
2024).
[Public, Environmental & Occupational Health 領域排名 46.7%]
Kuan-Chu Hou, Yen-Ching Chen*, Ta-Fu Chen, Yu Sun, Li-Li We, Ping-Keung Yip, Yi-Min Chu, Jeng-Min Chiou, Jen-Hau Chen*
Journal of the Formosan Medical
Association 6:S0929-6646(24)00218-3 (May 2024).
[Medicine, General & Internal 領域排名 21.4%]
Tao-Chun Peng, Jeng-Min Chiou, Yen-Ching Chen*, Jen-Hau Chen*
Journal of Nutrition, Health and Aging
28(1): 100004 (January 2024).
[Geriatrics & Gerontology 領域排名 25%]
Mu-Cyun Wang, Jeng-Min Chiou, Yen-Ching Chen*, Jen-Hau Chen*
Journal of Alzheimer’s Disease
2477-2488 (December 2023).
[Neuroscience 領域排名 37.3%]
Chaoming Huang, Sheng-Jean Huang, Tai-Yin Wu*, Yen-Ching Chen, Sheng-Huang Hsiao, Dachen Chu
QJM: An International Journal of
Medicine, hcad246 (October 2023).
[Medicine, General & Internal 領域排名 6.5%]
Ting-Yu Wu, Yi-Ting Hsieh, Yu-Hsin Wang, Jeng-Min Chiou, Ta-Fu Chen, Liang-Chuan Lai, Jen-Hau Chen*, Yen-Ching Chen*
Journal of Formosan Medical
Association. 122(10): 1050-1060 (October 2023).
[Medicine, General & Internal 領域排名 21.4%]
Yen-Ching Chen, Pei-Iun Hsieh, Jia-Kun Chen, Emily Kuo, Hwa-Lung Yu, Jeng-Min Chiou, Jen-Hau Chen*.
Environmental Research 233(15): 115483
(September 2023).
[Public, Environmental & Occupational Health 領域排名 4.8%]
Ching-Jow Hsieh, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen*, Jen-Hau Chen*.
Journal of Formosan Medical
Association 122(8): 7990-799 (August 2023).
[Medicine, General & Internal 領域排名 21.4%]
Ling-Wei Chen, Yi-Chun Chou, Meei-Shyuan Lee, Jeng-Min Chiou, Jen-Hau Chen*, Yen-Ching Chen*.
Clinical Nutrition 42(6): 879-886
(June 2023).
[Nutrition & Dietetics 領域排名 9.3%]
Tao-Chun Peng, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen*, Jen-Hau Chen*.
Journal of the American Medical
Directors Association 24(3): 292-298.e1 (March 2023).
[Geriatrics & Gerontology 領域排名 23.6%]
Pei-Iun Hsieh, Yen-Ching Chen, Jeng-Min Chiou, Jen-Hau Chen*.
Innovation in Aging 7(2): 1-13
(February 2023).
[Gerontology 領域排名 3.2%]
Yun-Ru Lu, Tzy-Haw Wu, Yachung Jeng, Wen-Yuan Lee, Wei-Chih Hsu, Amy Ming-Fang Yen, Shin-Liang Pan, Yen-Ching Chen, Sam Li-Sheng Chen, Hsiu-Hsi Chen, Horng-Huei Liou*.
Frontiers in Public Health 10:1005252
(January 2023).
[Public, Environmental & Occupational Health 領域排名 28.1%]
Jennifer Young Tu, Grace Jin, Jen-Hau Chen*, Yen-Ching Chen*.
Journal of Alzheimer’s Disease 86(4):1527-1543 (March 2022).[Neuroscience 領域排名3 7.3%]
B. 骨質疏鬆流行病學研究
- 非酒精性脂肪肝和骨質密度低下、骨質疏鬆及其導 致的骨折有關
(種族間有差異)
Ying-Hao Su, Kuo-Liong Chien, Shu-Hua Yang, Wei-Tso Chia, Jen-Hau Chen, Yen-Ching Chen*.
Journal of Bone Mineral Research 38(8):1092-1103 (August 2023).
- 首次加入血清鹼性磷酸酶建立比傳統預測骨質疏鬆風險評估工具更加預測能力的模型
Predicting the risk of osteopenia for women aged 40–55 years.
Jen-Hau Chen, Yen-Ching Chen, Min-Kuang Tsai, Jeng-Min Chiou, Wen-Chung Lee, Chwen-Keng Tsao, Keh-Sung Tsai , Wei-Chu Chie.
Journal of the Formosan Medical Association. 116(11): 888-896 (November 2017).
- 腎功能、停經狀態與中年婦女骨質密度的關係
Association of renal function and menopausal status with bone mineral density in middle-aged women.
Yueh-Hsuan Sheng, Jen-Hau Chen, Jeng-Min Chiou, Keh-Sung Tsai, Yue-Yuan Lee, Chwen-Keng Tsao, Yen-Ching Chen*.
Scientific Reports 5: 14956 (October 2015).
- 同時與骨質生成及破壞有關的SPP1基因多型性與中年婦女骨密度之關聯
Jen-Hau Chen, Yen-Ching Chen, Chien-Lin Mao, Jeng-Min Chiou, Chwen Keng Tsao, Keh-Sung Tsai.
PLOS ONE 9(5): e97428 (May 2014).
台灣流行病學會 研究生論文獎
- 首次探討代謝體學和骨質密度的流行病學研究
Ying-Shu You, Ching-Yu Lin, Hao-Jan Liang, Shen-Hung Lee, Keh-Sung Tsai, Jeng-Min Chiou, Yen-Ching Chen, Chwen-Keng Tsao, Jen-Hau Chen
Journal of Bone and Mineral Research 29(1): 212-22 (January 2014).
C. 攝護腺癌遺傳流行病學研究
- Polymorphisms
of an innate immune gene, toll-like receptor 4, and aggressive
prostate cancer risk: A systematic review and meta-analysis.
Pei-Hsuan Weng, Yi-Ling Huang, John H. Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S. Witte, Rosalind A. Eeles, Douglas F. Easton, David E. Neal, Jenny Donovan, Freddie C. Hamdy, Kenneth R. Muir, Graham Giles, Gianluca Severi, Jeffrey R. Smith, Carmela R. Balistreri, Irene M. Shui, Yen-Ching Chen*.
PLoS ONE 9(10): e110569 (October 2014).
- Genetic
polymorphisms of the glycine N-methyltransferase and prostate
cancer risk in the Health Professionals Follow-up Study.
Marcelo Chen, Yi-Ling Huang, Yu-Chuen Huang, Irene M. Shui, Edward Giovannucci, Yen-Ching Chen**, Yi-Ming Arthur Chen.
PLOS ONE 9(5): e94683 (May 2014).
- Prospective
study of effect modification by toll-like receptor 4 variation
on the association between Trichomonas vaginalis serostatus and
prostate cancer.
Yen-Ching Chen*, Yi-Ling Huang, Elizabeth A. Platz, John F. Alderete, Lu Zheng, Jennifer R. Rider, Peter Kraft, Edward Giovannucci, Siobhan Sutcliffe.
Cancer Causes Control 24(1): 175-180 (January 2013).
- Cancer
and inflammation: Promise for biological therapy.
Sandra Demaria, Eli Pikarsky, Michael Karin, Lisa M. Coussens, Yen-Ching Chen, Emad M. El-Omar, Giorgio Trinchieri, Steven M. Dubinett, Jenny T. Mao, Eva Szabo, Arthur Krieg, George Weiner, Bernard A. Fox, George Coukos, Ena Wang, Robert T. Abraham, Michele Carbone, and Michael T. Lotze.
Journal of Immunotherapy 33(4):335-51 (May 2010).
- Family
history of prostate and breast cancer and the risk of prostate
cancer in the PSA era.
Yen-Ching Chen*, John H. Page, Rong Chen, Edward Giovannucci
The Prostate 68(14):1582-91 (October 2008).
- Association between
genetic polymorphisms of macrophage scavenger receptor 1 (MSR1)
gene and risk of prostate cancer in the Health Professionals
Follow-Up Study.
Yen-Ching Chen*, Edward Giovannucci, Peter Kraft, David J. Hunter.
Cancer Epidemiology, Biomarkers& Prevention 17(4):1001-1003 (April 2008).
- Sequence
variants of elaC homolog 2 (Escherichia coli) (ELAC2)
gene and susceptibility to prostate cancer in the Health
Professionals Follow-Up Study.
Yen-Ching Chen*, Edward Giovannucci, Peter Kraft, David Hunter.
Carcinogenesis 29(5):999-1004 (May 2008).
- Association
between toll-like receptor gene cluster (TLR6, TLR1,
and TLR10) and prostate cancer.
Yen-Ching Chen*, Edward Giovannucci, Peter Kraft, Ross Lazarus, David J. Hunter.
Cancer Epidemiology, Biomarkers & Prevention 16(10):1982-1989 (October 2007).
- Sequence variants of
estrogen receptor β and risk of prostate cancer in the National
Cancer Institute Breast and Prostate Cancer Cohort Consortium.
Yen-Ching Chen*, Peter Kraft, Philip Bretsky, Shamika Ketkar, David J. Hunter, Demetrius Albanes, David Altshuler, Gerald Andriole, Christine D. Berg, Heiner Boeing, Noel Burtt, Bas Bueno-de-Mesquita, Howard Cann, Federico Canzian, Stephen Chanock, Alison Dunning, Heather S. Feigelson, Matthew Freedman, J. Michael Gaziano, Edward Giovannucci, Maria-Jose Sanchez, Christopher A. Haiman, Goran Hallmans, Richard B. Hayes, Brian E. Henderson, Joel Hirschhorn, Rudolf Kaaks, Timothy J. Key, Laurence N. Kolonel, Loic LeMarchand, Jing Ma, Kim Overvad, Domenico Palli, Paul Pharaoh, Malcolm Pike, Eliot Riboli, Carmen Rodriguez, V. Wendy Setiawan, Meir Stampfer, Daniel O. Stram, Gilles Thomas, Michael J. Thun, Ruth C. Travis, Jarmo Virtamo, Antonia Trichopoulou, Sholom Wacholder, Stephanie J. Weinstein.
Cancer Epidemiology, Biomarkers & Prevention 16 (10):1973-1981 (October 2007).
- A
candidate gene approach to searching for low-penetrance breast
and prostate cancer genes- The National Cancer Institute Breast
and Prostate Cancer Cohort Consortium.
David J. Hunter, Elio Riboli, Chris A. Haiman, Demetrius Albanes, David Altshuler, Stephen J. Chanock, Richard B. Hayes, Brain E. Henderson, Rudolf Kaaks, Daniel O. Stram, Gilles Thomas, Michael J. Thun(writing committee), Helene Blanche, Julie E. Buring, Noel P. Burtt, Eugenia E. Calle, Howard Cann, Federico Canzian, Yen-Ching Chen, Graham A. Colditz, David G. Cox, Alison M. Dunning, Heather S. Feigelson, Matthew L. Freedman, J. Michael Gaziano, Edward Giovannucci, Susan E. Hankinson, Joel N. Hirschhorn, Robert N. Hoover, Timothy Key, Laurence N. Kolonel, Peter Kraft Loic Le Marchand, Simin Liu, Jing Ma, Sandra Melinick, Paul Pharaoh, Malcolm C. Pike, Carmen Rodriguez, Wendy V. Setiawan, Meir J. Stampfer, Edward Trapido, Ruth Travis, Jorma Virtamo, Sholom Wacholder, Walter C. Willett.
Nature Reviews Cancer 5(12): 977-985 (December 2005).
- Sequence
variations of toll-like receptor 4 (TLR4) and
susceptibility to prostate cancer.
Yen-Ching Chen*, Edward Giovannucci, Ross Lazarus, Peter Kraft, Shamika Ketkar, David Hunter.
Cancer Research 65(24): 11771-11778 (December 2005).
- Genetic variation in
the HSD17B1 gene and risk of prostate cancer.
Peter Kraft, Paul Pharoah, Stephen J. Chanock, Demetrius Albanes, Laurence N. Kolonel, Richard B. Hayes, David Altshuler, Gerald Andriole, Christine Berg, Heiner Boeing, Noel P. Burtt, Bas Bueno-de-Mesquita, Eugenia E. Calle, Howard Cann, Federico Canzian, Yen-Ching Chen, David E. Crawford, Alison M. Dunning, Heather S. Feigelson, Matthew L. Freedman, John M. Gaziano, Ed Giovannucci, Carlos Alberto Gonzalez, Christopher A. Haiman, Goran Hallmans, Brian E. Henderson, Joel N. Hirschhorn, David J. Hunter, Rudolf Kaaks, Timothy Key, Loic Le Marchand, Jing Ma, Kim Overvad, Domenico Palli, Malcolm C. Pike, Elio Riboli, Carmen Rodriguez, Wendy V. Setiawan, Meir J. Stampfer, Daniel O. Stram, Gilles Thomas, Michael J. Thun, Ruth Travis, Antonia Trichopoulou, Jarmo Virtamo, Sholom Wacholder.
PLoS Genetics 1(5): 603-613 (November 2005).
- Sex
steroid hormones and the androgen receptor gene CAG
repeat and subsequent risk of prostate cancer in the PSA era.
Elizabeth A. Platz, Michael F. Leitzmann, Nader Rifai, Philip W. Kantoff, Yen-Ching Chen, Meir J. Stampfer, Walter C. Willett, and Edward Giovannucci.
Cancer Epidemiology, Biomarkers & Prevention 14(5):1262-1269 (May 2005).
D. 砷暴露之癌症流行病學研究
- Early-life
or lifetime sun exposure, sun reaction, and the risk of squamous
cell carcinoma in an Asian population.
Yen-Ching Chen, David C. Christiani, Huey-Jen Jenny Su, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Sheau-Chiou Chao, Julia Yu-Yun Lee, Yue-Liang Leon Guo.
PLoS ONE 9(10): e110569 (October 2014).
- Arsenic
methyaltion, GSTT1, GSTM1, GSTP1 polymorphisms,
and skin lesions.
Kathleen M. McCarty, Yen-Ching Chen, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mahiuddin, Yu-Mei Hsueh, Li Su, Thomas Smith, Louise Ryan, David C. Christiani.
Environmental Health Perspectives 115(3): 341-345 (March 2007).
- Interaction
between environmental tobacco smoke and arsenic methylation
ability on the risk of bladder cancer.
Yen-Ching Chen*, Huey-Jen Jenny Su, Yu-Liang Leon Guo, E. Andres Houseman, David C. Christiani
Cancer Causes & Control 16 (2): 75-81 (March 2005).
- Polymorphisms in
GSTT1 and p53 and urinary transitional cell
carcinoma in south-western Taiwan: A preliminary study.
Yen-Ching Chen*, Lilian Xu, Huey-Jen Jenny Su, Yu-Liang Leon Guo, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee, David C. Christiani.
Biomarkers 9 (4-5): 386-394 (July-October 2004).
- Arsenic methylation
and bladder cancer risk in Taiwan.
Yen-Ching Chen, Huey-Jen Jenny Su, Yu-Liang Leon Guo, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee, David C. Christiani.
Cancer Causes & Control 14(4): 303-310 (May 2003).
- Arsenic
methylation and skin cancer risk in southwestern Taiwan.
Yen-Ching Chen, Yu-Liang Leon Guo, Huey-Jen Jenny Su, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee, Sheau-Chiou Chao, Julia Yu-Yun Lee, David C. Christiani.
Journal of Occupational and Environmental Medicine 45(3): 241-248 (March 2003).
- Genetic
polymorphism in p53 codon 72 and skin cancer in
southwestern Taiwan.
Yen-Ching Chen, Lilian Xu, Yu-Liang Leon Guo, Huey-Jen Jenny Su, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee, Sheau-Chiou Chao, Julia Yu-Yun Lee, David C. Christiani.
Journal of Environmental Science and Health, Part A (Toxic/Hazardous Substances and Environmental Engineering) A38(1): 201-211 (January 2003).
- Stability
of arsenic species and insoluble arsenic in human urine.
Yen-Ching Chen, Chitra J. Amarasiriwardena, Yu-Mei Hsueh, David C. Christiani.
Epidemiology, Biomarkers & Prevention 11(11): 1427-1433 (November 2002).
- Determination
of total arsenic in groundwater and human urine by
graphite-furnace atomic-absorption spectrophotometry.
Yen-Ching Chen, Hou-Chuan Wang, Shih-Yen Cheng, Chia-Hsin Yen, Mao-Sung Kuo.
Journal of the Environmental Protection Society of the Republic of China 19(2): 14-20 (December 1996).
E. 其他癌症流行病學研究
- Use
of germline polymorphisms in predicting concurrent
chemoradiotherapy response in esophageal cancer.
Pei-Chun Chen, Yen-Ching Chen**, Liang-Chuan Lai, Mong-Hsun Tsai, Shin-Kuang Chen, Pei-Wen Yang, Yung-Chie Lee, Chuhsing K. Hsiao, Jang-Ming Lee, Eric Y. Chuang.
International Journal of Radiation Oncology, Biology, Physics 82(5): 1996-2003 (April 2012).
- Human
papilloma virus and female lung adenocarcinoma.
Yao-Jen Li, Yu-Chin Tsai, Yen-Ching Chen*, David C. Christiani.
International Journal of Radiation Oncology, Biology, Physics 82(5): 1996-2003 (April 2012).
- Molecular
epidemiology of cancer.
Yen-Ching Chen, David J. Hunter.
CA: A Cancer Journal for Clinicians 55(1): 45-54 (January-February 2005).
- Lung
adenocarcinoma and human papillomavirus infection.
Yen-Ching Chen, Jen-Hau Chen, Kradin Richard, Pao-Yang Chen, David C. Christiani.
Cancer 101(6): 1428-1436 (September 2004).
- Chapter
2: Genetic Susceptibility to Second-Hand Smoke.
Yen-Ching Chen, Jen-Hau Chen, David C Christiani.
'Smoking and Health Research Frontiers' Calvin B. Fong (Ed.) Nova Science Publishers, Hauppauge, NY (2007) p.9-61. ISBN: 1-60021-480-0
F. 其他研究
- Metabolomic
analysis of platelets of patients with aspirin non-response.
Jiun-Yang Chiang, Sheng-Han Lee, Yen-Ching Chen, Cho-Kai Wu, Huei-Ming Yeh, Shih-Fan S. Yeh, Cheng-An Hsu, Bin-Bin Lin, Pi-Chu Chang, Chih-Hsin Chang, Hao-Jan Liang, Fu-Tien Chiang, Chin-Yu Lin, Jyh-Ming J. Juang.
Front Pharmacol. DOI: 10.3389/fphar.2019.01107 (August 2019).
- Switching
antipsychotic treatment to aripiprazole in psychotic patients
with neuroleptic-induced tardive dyskinesia: a 24-week follow-up
study.
Chia-Hsiang Chan, Hung-Yu Chan, Yen-Ching Chen*.
Int Clin Psychopharmacol. 33(3):155-162 (May 2018).
- Vegetarian
diet, food substitution, and nonalcoholic fatty liver.
Tina H. Chiu, Ming-Nan Lin, Wen-Harn Pan, Yen-Ching Chen, Chin-Lon Lin.
Tzu Chi Medical Journal. 30(2):102-109 (April 2018).
- Interplay
between superoxide dismutase, glutathione peroxidase, and
peroxisome proliferator activated receptor gamma polymorphisms
on the risk of end-Stage renal disease among Han Chinese
patients.
Chia-Ter Chao, Yen-Ching Chen, Chih-Kang Chiang, Jenq-Wen Huang, Cheng-Chung Fang, Chen-Chih Chang and Chung-Jen Yen.
Oxidative Medicine and Cellular Longevity. Volume 2016, Article ID 8516748, 7 pages (January 2016).
- Sequence
variants of peroxisome proliferator-activated receptor-gamma
gene and the clinical courses of patients with end-stage renal
disease
Chia-Ter Chao, Yen-Ching Chen**, Chih-Kang Chiang, Jenq-Wen Huang, Fu-Chang Hu, Cheng-Chung Fang, Chen-Chih Chang and Chung-Jen Yen
Disease Markers. Article ID 763459 (February 2015).
- Genetic
variability in serotonin receptor and transporter genes may
influence risk for tardive dyskinesia in chronic schizophrenia.
Ching-Jow Hsieh, Yen-Ching Chen, Mei-Shu Lai, Chen-Jee Hong, Kuo-Liong Chien.
Psychiatry Res. 188(1): 175-6 (June 2011).
- Common
sequence variants in pharmacodynamic and pharmacokinetic
pathway-related genes conferring LDL cholesterol response to
statins.
Kuo-Liong Chien, Kuei-Chen Wang, Yen-Ching Chen, Chia-Lung Chao, Hsiu-Ching Hsu, Ming-Fong Chen & Wei J Chen.
Pharmacogenomics 11: 309-317 (March 2010).
- Pediatric
empyema: Outcome analysis of thoracoscopic management.
Jin-Shing Chen, Kai-Chieh Huang, Yen-Ching Chen, Hsao-Hsun Hsu, Shuenn-Wen Kuo, Pei-Ming Huang, Jan-Ming Lee, Yung-Chie Lee.
Journal of Thoracic and Cardiovascular Surgery 137(5): 1195-1199, (May 2009).
- A
comparative study of formaldehyde levels in industrial waste
water by colorimetric, GC, and HPLC methods.
Yen-Ching Chen, Mao-Sung Kuo.
Journal of Environmental Protection Society of the Republic of China. 18(2): 24-38 (December 1995).
- Determination
of total selenium in human urine and serum by graphite-furnace
atomic-absorption spectrophotometry with
palladium-nickel-ammonium nitrates as a matrix modifier.
Chih-Ming Kao, Yunn-Jing Cherng ( Yen-Ching Chen) , Ming-Hong Wung, Pi-Yuan Tsao, Mao-Sung Kuo.
Journal of the Chinese Chemical Society 40(1): 33-39 (January-February 1993).
