2010 Prof. of IOB, NTU
2006 Associate Prof. of IOB, NTU
2006 Associate Prof. of MC, NTU
2004 Associate Prof. of NTUH
1999 Visitor researcher of MIT
1989 VS. of NTUH
Publication
Lee IN, Chen CH, Sheu JC, Lee HS, Huang GT, Chen DS, Yu CY, Wen CL, Lu FJ, Chow LP. Identification of complement C3a as a candidate biomarker in human chronic hepatitis C and HCV-related hepatocellular carcinoma using a proteomics approach. Proteomics 2006;6:2865-2873.
Lee CZ, Lee HS, Huang GT, Yang PM, Sheu JC. Detection of YMDD mutation using mutant-specific primers in chronic hepatitis B patients before and after lamivudine treatment. World J Gastroenterol 2006;12:5301-5305.
Lo W, Teng SW, Tang HY, Kim KH, Chen HC, Lee HS, Chen YF, So PT, Dong CY. Intact corneal stroma visualization of GFP mouse revealed by multiphoton imaging. Microsc Res Tech 2006;69:973-975.
Lee HS*, Teng SW, Chen HC, Lo W, Lin TY, Chiou LL, Jiang CC, Dong CY*. Imaging human bone marrow stem cell morphogenesis in PGA scaffold by multiphoton microscopy. Tissue Eng 2006;12:2835-2841.
Liu Y, Chen HC, Lo W, Chiou LL, Huang GT, Dong CY*, Lee HS*. Visualization of hepatobiliary excretory function by intravital multiphoton microscopy. J Biomed Optics 2007;12:014014.
Chen CH, Yang PM, Huang GT, Lee HS, Sung JL, Sheu JC. Estimation of seroprevalence of hepatitis B virus and hepatitis C virus in Taiwan from a large-scale survey of free hepatitis screening participants. J Formos Med Assoc 2007;106:148-155.
Su PF, Lee TC, Lin PJ, Lee PH, Jeng YM, Chen CH, Liang JD, Chiou LL, Huang GT*, Lee HS*. Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma. Int J Cancer 2007;121: 1257- 1264.
Chen CH, Lee HS, Huang GT, Yang PM, Yu WY, Cheng KC, Lee PH, Jeng YM, Chen DS, Sheu JC. Phenotypic analysis of tumor-infiltrating lymphocytes in hepatocellular carcinoma. Hepatogastroenterology 2007;54:1529-1533.
Chou HC, Chen CH, Lee HS, Lee CZ, Huang GT, Yang PM, Lee PH, Sheu JC. Alterations of tumour suppressor gene PPP2R1B in hepatocellular carcinoma. Cancer Lett 2007;253:138- 143.
Chiu CC. Huang GT, Chou SH, Chien CT, Chiou LL, Chang MH, Lee HS*, Chen DS. Characterization of cytokeratin 19-positive hepatocyte foci in the regenerating rat liver after 2-AAF/CCl4 injury. Histochem Cell Biol 2007;128:217-226.
Chou CK, Chen WL, Fwu PT, Lin SJ, Lee HS, Dong CY. Polarization ellipticity compensation in polarization second-harmonic generation microscopy without specimen rotation. J Biomed Opt. 2008 Jan-Feb;13(1):014005.
Sun Y, Tan HY, Lin SJ, Lee HS, Lin TY, Jee SH, Young TH, Lo W, Chen WL, Dong CY. Imaging tissue engineering scaffolds using multiphoton microscopy. Microsc Res Tech 2008;71:140-145.
Hsieh CH, Lee MC, Tsai-Wu JJ, Chen MH, Lee HS, Chiang H, Herbert Wu CH, Jiang CC. Deleterious effects of MRI on chondrocytes. Osteoarthritis Cartilage 2008;16:343-51.
Lin CC, Liang HP, Lee HS, Huang GT, Yang PM, Ho MC, Lee PH, Tsang YM, Chen DS, Sheu JC, Chen CH. Clinical manifestations and survival of hepatocellular carcinoma patients with peritoneal metastasis. J Gastroenterol Hepatol 2009;24:815-20.
Li WJ, Chiang H, Kuo TF, Lee HS, Jiang CC, Tuan RS. Evaluation of articular cartilage repair using biodegradable nanofibrous scaffolds in a swine model: a pilot study. J Tissue Eng Regen Med 2009;3:1-10.
Li FC, Liu Y, Huang GT, Chiou LL, Liang JH, Dong CY*, Lee HS*. In vivo dynamic metabolic imaging of obstructive cholestasis in mice. Am J Physiol- Gastrointest Liver Physiol 2009;296:1091-1097.
Lin BR, Yu CJ, Chen WC, Lee HS, Chang HM, Lee YC, Chien CT and Chen CF. Green tea extract supplement reduces D-galactosamine-induced acute liver injury by inhibition of apoptotic and proinflammatory signaling. J Biomed Sci 2009; 25;16:35.
Tien YW, Wu YM, Lin WC, Lee HS, Lee PH. Pancreatic carcinoma cells stimulate proliferation and matrix synthesis of hepatic stellate cells. J Hepatol 2009;51:307-314.
Chiu CC, Sheu JC, Chen CH, Lee CZ, Chiou LL, Chou SH*, Huang GT*, Lee HS*. Global gene expression profiling reveals a key role of CD44 in hepatic oval cell reaction after 2-AAF/CCl4 injury in rodents. Histochem Cell Biol 2009; 132:479-489.
Chiu CC, Huang YW, Chou SH, Huang GT, Chiou LL, Lee HS*. Generation of a monoclonal antibody specifically reacting with undifferentiated liver progenitor cells. Hybridoma 2009; 28:435-439.
Tai CC, Chen CY, Lee HS, Wang YC, Li TK, Mersamm HJ, Ding ST, Wang PH. Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism. J Biol Chem 2009; 284: 32239-32247.
Chen WL, Huang CH, Chiou LL, Chen TH, Huang YY, Jiang CC, Lee HS*, Dong CY*. Multiphoton imaging and quantitative analysis of collagen production by chondrogenic human mesenchymal stem cell cultured in chitosan scaffold. Tissue Engineering Part C 2010;16:913-920.
Sun TL, Liu Y, Sung MC, Chen HC, Yang CH, Hovhannisyan V, Lin WC, Jeng YM, Chen WL, Chiou LL, Huang GT, Kim KH, So PT, Chen YF, Lee HS*, Dong CY*. Ex vivo imaging and quantification of liver fibrosis using second-harmonic generation microscopy. J Biomed Opt 2010;15:036002.
Su PJ, Chen WL, Li TH, Chou CK, Chen TH, Ho YY, Huang CH, Chang SJ, Huang YY, Lee HS*, Dong CY*. The discrimination of type I and type II collagen and the label-free imaging of engineered cartilage tissue. Biomaterials 2010;31:9415-9421.
Tseng YW, Wang PH, Lee HS, Liu BH, Mersmann HJ, Lin EC, Ding ST. Regulation of the expression of angiotensin converting enzyme 2 by polyunsaturated fatty acids in porcine adipocytes. J Anim Sci 2010;88:3563-3567.
Wu YM, Kao CY, Huang YJ, Yu IS, Lee HS, Lai HS, Lee PH, Lin CN, Lin SW. Genetic modification of donor hepatocytes improves therapeutic efficacy for hemophilia B in mice. Cell Tranplant 2010;19:1169-1180.
Sun TL, Liu Y, Sung MC, Chen HC, Yang CH, Hovhannisyan V, Lin WC, Chiou LL, Huang GT, Kim K, So PTC, Lee HS*, Dong CY*. Label-free diagnosis of human hepatocellular carcinoma by multiphoton autofluorescence microscopy. Appl Phys Lett (in press)