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National Taiwan University  School of Medicine and School of Engineering

Institute of Biomedical Engineering

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Cell and Tissue Engineering Laboratory

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Book Chapter

  • Chao PG (2017). Crimped Electrospun Fibers for Tissue Engineering In: Biomaterials for Tissue Engineering (Ed. Chawla K): Springer, NY, NY.
  • Chahine NO, Chao PG (2011). Influence of Micro and Nanotechnologies on Tissue Engineering and Biomaterials, in Biomaterials for Tissue Engineering: A Review of the Past and Future Trends (Eds. Mauck RL and Burdick JA), Springer, NY, NY.
  • Grayson W, Chao PG, Marolt D, Radisic M, Cannizzaro C, Figallo E and Vunjak-Novakovic G (2007) Bioreactors for tissue engineering and regenerative medicine, in Translational Approaches in Tissue Engineering and Regenerative Medicine (Eds. Mao et al), Artech House, Norwood, MA.
  • Tang Z, Chao PG, Tucay A, Takai E, Djukic D, Lind ML, Hung CT, Guo EX, West AC, Osgood R, Yardley JT (2003). XYZ on a chip: Nanoscale fabrication, fluidics, and optics directed toward applications with biology and medicine. In Organic Nanophotonics (Eds. Charra F et al), Kluwer Academics, Netherlands, 127-138.

Journal Articles

Selected Abstracts

  • Chang CW, Chao PG (2018). Collagen Enhances Cell Infiltration in Dense Fibrous Scaffold. New Orleans, LA.
  • Lin BJ, Tsao SH, Chao PG (2018). Lipid Rafts Sense and Direct Electric Field-induced Migration. BMES-CMBE, Key Largo, FL.
  • Lin BJ, Tsao SH, Chen A, Hu SK, Chao L, Chao PG (2017). Electric Fields Coalesce Lipid Raft and Caveolin to Direct Cell Migration. ASCB, Philadelphia, PA.
  • Wen WC, Chao PG (2017). Anisotropic YAP mechanotransduction. SB3C, Tucson, AZ.
  • Wen SM, Chao PG (2017). Myosin mediates anisotropic mechanosensing. SB3C, Tucson, AZ.
  • Lee JH, Chao PG (2017). Electrospinning with Porogen in Tissue Engineered Constructs. Trans ORS 42; San Diego, CA.
  • Fu KJ, Chao PG (2017). Wavy Structures Change Nuclear Shape and Mechanotransduction. BMES-CMBE, Big Island, HI.
  • Szczesny SE, Liu PC, Driscoll TP, Mauck RL, Chao PG (2016). Engineered Nanofiber Crimp Alters Scaffold Mechanics and Mesenchymal Stem Cell Mechanotransduction, Trans ORS 41; Orlando FL.
  • Chang HY, Chao PG (2015). Effects of Dynamic Stretch on Caveolin Phosphorylation and Focal Adhesion Dynamics, ASCB; San Diego, CA.
  • Fu KJ, Chao PG (2015). Wavy Cells Control Nuclear Morphology through Actin Network, ASCB; San Diego, CA.
  • Wen SM, Chao PG (2015). Role of Cell Tension on Anisotropic Mechanosensing. SB3C, Snowbird, UT.
  • Tsao SH, Chao PG (2015). Role of Src in Electric Field-induced Directed Cell Migration. SB3C, Snowbird, UT.
  • Tsao SH, Lin BJ, Chao PG (2015). Lipid Raft and caviolin-1 Polarization Guide Fibroblast Directional Migration in Electric Field. Trans ORS 40; Las Vegas, NV, 503.
  • Chen CA, Chao PG (2015). Differential Mechanical Regulation of Nuclear Morphology in Wavy Structures. Trans ORS 40; Las Vegas, NV, 508
  • Tsao SH, Lin BJ, Chao PG (2014) Lipid Rafts Mediates Electric Field-induced Directional Migration, ASCB Annual Meeting; Philadelphia, PA.
  • Chao PG (2014). Lipid Rafts Mediate Electric Field-directed Cell Migration, GCBME/APCMBE; Tainan, Taiwan.
  • Chao PG (2014). Microcrimped Electrospun Fiber for Ligament Tissue Engineering, ISOMRM; Taoyuan, Taiwan.
  • Chao PG (2014). Micro-composite Substrates for the Study of Cell-Matrix Mechanical Interactions, WCB; Boston, MA (Invited Talk).
  • Wen SM, Chao PG (2014). Interaction of Mechanical Stretch and Cell Morphology on Actin Organization and Nuclear Shape, WCB; Boston, MA.
  • Hsu HY, Tseng HY, Chao PG (2014). Synergistic Effects of Wavy Fiber Morphology and Dynamic Mechanical Loading on Ligament Fibroblasts, IWMM; Hong Kong.
  • Chang J, Tseng H, Chao PG (2014). Ligament Tissue Engineering with Wavy Electrospun PLLA Fibers, Trans ORS 39; New Orleans, LA, 513.
  • Driscoll TP, Chang J, Keyes T, Hast WH, Heo SJ, Mauck RL, Chao PG (2014). Engineered Fiber Crimp Alters Scaffold Mechanics, Cell Shape, and Strain Transfer to the Nucleus, Trans ORS 39; New Orleans, LA, 502.
  • Chiu Y, Hsu Y, Tsui C, Lin J, Chao PG, Wang J (2014). Type II Collagenase Injection Simulated Intervertebral Disc Degeneration Process Both Biochemically and Biomechanically, Trans ORS 39; New Orleans, LA, 700.
  • Hsu Y, Chiu Y, Tsui C, Chao PG, Wang J (2014). Rheological Changes of Intervertebral Disc after Glycation and Enzymatic Digestion, Trans ORS 39; New Orleans, LA, 1586.
  • Yuan X, Chao PG, G Vunjak-Novakovic (2014). Meniscus Extracellular Matrix Hydrogel For Stem Cell-based Tissue Repair, Trans ORS 39; New Orleans, LA, 458.
  • Chao PG (2014) Role of Lipid Rafts in Electric Field-induced Directional Migration. 2014 CMBE Conference, La Jolla, CA (Rising Star Presentation).
  • Wen SM, Chao PG (2013). Interactions between Cell and Nuclear Morphology and Mechanical Stretch. EAC-BME 2013, Taipei, Taiwan.
  • Wen SM, Chao PG (2013). Spatial Actin Structure does not Correlate with Nuclear Organization. ASME 2013 Summer Bioengineering Conference; Sunriver, OR, 14167.
  • Sung CH, Chao PG (2013). Effects of Wavy Microgroove Structure on Ligament Fibroblast Cell and Nuclear Morphology. ASME 2013 Summer Bioengineering Conference; Sunriver, OR, 14449.
  • Tseng HY, Hsu HY, Chao PG (2013). Effects of 3D Wavy Fiber Structure on Ligament Fibroblast Morphology and Gene Expression with Tensile Loading. Trans ORS 38; San Antonio, TX, 450.
  • Lin BJ, Chao PG (2013). Electric Field-induced Lipid Raft Polarization Guide Fibroblast Directional Migration. Trans ORS 38; San Antonio, TX, 588.
  • Tseng HY, Chao PG (2013). Effects of Sacrificial Fibers on PLLA Fiber Crimp. Trans ORS 38; San Antonio, TX, 452.
  • Cheng YC, Chao PG (2012). Collagen Gel with Aligned Fibers Modulate Electric Field-directed Migration of Ligament Fibroblasts. 2012 TERMIS; Vienna, Austria, 26.P11.
  • Wen SM, Chao PG (2012). Temporal Cell Morphology Response to Mechanical Stimulation. ASME 2012 Summer Bioengineering Conference; Fajardo, Puerto Rico, 80939.
  • Cheng YC, Tsai CH, Chao PG (2012). a2b1 Integrin Mediates Electric Field-Induced Directed Ligament Fibroblast Migration via RhoA, Trans ORS 37; San Francisco, CA, 38.
  • Wen SM, Tan AR, Hung, CT, Chao PG (2012). Chondrocyte Migration is Modulated by Osmotic Environment, Trans ORS 37; San Francisco, CA, 1825.
  • Shen SC, Chang WR, Chao PG (2012). Cell-type Specific Migration Response to Substrate Thickness/Stiffness Gradient, Trans ORS 37; San Francisco, CA, 1625.
  • Hsu HY, Liu CY, Chao PG (2012). Electrospun Wavy Fibers Modulate Loading-Induced Cell Alignment, Trans ORS 37; San Francisco, CA, 637.
  • Cheng YC, Feng CH, Chao PG (2012). Substrate Thickness Modulates Electric Field-induced Ligament Fibroblast Migration, Trans ORS 37; San Francisco, CA, 636.
  • Cheng YC, Chao PG (2011). A Model for Ligament Fibroblast Migration Into Provisional Matrix; 2011 ASME Bioengineering Summer Conference; Farmington, PA, 53858.
  • Chang WR, Chao PG (2011). Effects Of Composite Substrate Microstructure On Fibroblast Morphology and Migration; 2011 ASME Bioengineering Summer Conference; Farmington, PA, 53859.
  • Feng CH, Yu SF, Shen SC, Chao PG (2011) Effects of 2D and 3D Collagen Fiber Orientation on Ligament Fibroblast Migration; Trans ORS 36; Long Beach, CA.
  • Tsai CH, Hsu HY, Chao PG (2011) Electrical Stimulation Waveforms from Physical Therapy Stimulate ACL Fibroblast Migration; Trans ORS 36; Long Beach, CA.
  • Liu CY, Chang WR, Tsai WB, and Chao PG (2010) Effect of Solvent on Electrospun PLLA fiber Mechanical Characteristics and Ligament Fibroblast Responses; 2010 Bioengineering Summer Conference; Naples FL.
  • Yodmuang S, Chao PG, Wang X, Sun L, Kaplan DL, and Vunjak-Novakovic (2010) Comparison of silk hydrogel and porous scaffolds for cartilage tissue engineering; Trans ORS 35; New Orleans, LA.
  • Yu S, Cheng Y, Liao C, Chu S, and Chao PG (2010) Ligament fibroblast migration on native matrices with applied DC electric field; Trans ORS 35; New Orleans, LA.
  • Liao C, Zhuo Z, Yu J, Chao PG, and Chu S (2010) In situ observation of collagen thermal denaturation by second harmonic generation microscopy; SPIE Photonics West , San Francisco, USA.
  • Tandon N, Goh B, Marsano A, Chao PG, Montouri-Sorrentino C, Gimble JM, and Vunjak-Novakovic G (2009). Alignment and Elongation of Human Adipose-Derived Stem Cells in Response to Direct-Current Electrical Stimulation. Conf Proc IEEE Eng Med Biol Soc.
  • Chu Y, Yu S, and Chao PG (2009) Corneal epithelial cells preferentially migrate on basement membrane, BMES 2009 Annual Symposium; Taipei, Taiwan.
  • Lima EG, Chao PG, Ateshian G, Cook JL, Bal BS, Vunjak-Novakovic G, and Hung CT (2009). Porous tantalum metal outperforms devitalized bone as a substrate for osteochondral tissue engineering; Trans ORS 34; Las Vegas, NV.
  • Chao PG, Yodmuang S, Grayson WL, Lima EG, Hung CT, Vunjak-Novakovic G (2008) Inhibition of Cartilage Formation by Decellularized Bone: Possible Mechanisms; Trans ORS 32; San Francisco, CA.
  • Chao PG, Yodmuang S, Wang XQ, Kaplan DL, Vunjak-Novakovic G (2008) Novel Silk Hydrogel for Tissue Engineering of Functional Cartilage; Trans ORS 32; San Francisco, CA.
  • Chao PG, Grayson WL, Lima EG, Schoeneck N, Vunjak-Novakovic G, Hung CT (2007). Effects of decellularized bone on cartilage development in engineered osteochondral constructs; Keystone Symposium; Snowbird, UT.
  • Chao PG, Bhumiratana S, Lima EG, Grayson WL, Hung CT, Vunjak-Novakovic G (2007). Increased transport rates in a novel osteochondral bioreactor with simultaneous medium perfusion and dynamic loading; Trans ORS 31; San Diego, CA.
  • Albro MB, Chao PG, Hung, CT, Ateshian G (2007). Partial volume recovery of chondrocytes upon osmotic loading explained by the cytoplasm¡¦s passive steric exclusion of select solute species. Trans ORS 31; San Diego, CA.
  • Oswald ES, Chao PG, Bulinski JC, Ateshian GA, Hung CT, in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society, 2006 pp. 3659-3661, New York, NY.
  • Grayson WL, Bhumiratana S, Chao PG, Vunjak-Novakovic G (2006). Engineering human osteochondral grafts using spatially-controlled multi-parametric stimulation. BMES. Chicago, IL.
  • Chao PG, Bulinski JC, Ateshian GA, Hung CT (2006). Effects of osmotic loading on chondrocyte nuclear size. Trans ORS 30, Chicago, IL.
  • Chao PG, Oswald ES, Hung CT (2006). Osmotic loading-induced volume and gene expression changes in chondrocytes involve calcium mobilization. Trans ORS 30, Chicago, IL.
  • Chao PG, Han S, Costa KD, Hung, CT (2005). Chondrocyte calcium signaling is modulated by dynamic osmotic loading. Trans ORS 29, 906.
  • Han S, Chao PG, Costa KD, Hung, CT (2005). Influence of serum on hypotonic loading-induced chondrocyte mechanotransduction. Trans ORS 29, 1633.
  • Chao PG, Navratil FR, Costa KD, and Hung CT (2004). Effects of Basal Osmolarity on Chondrocyte Cell Size and Calcium Response to Step Osmotic Loading. BMES 2004, Philadelphia, PA.
  • Likhitpanichkul M, Chao PG, Hung CT, G. Ateshian (2004). Determination of modulus and permeability of chondrocytes from cell response to osmotic loading. The European Society of Biomechanics Meeting.
  • Chao PG, Cannon AM, Costa KD, Hung CT (2004). Effects of basal osmolarity on chondrocyte transient behavior to step osmotic loading. Trans ORS 50, 538.
  • Chao PG, Tang Z, West AC, and Hung CT (2003). Chondrocyte Size Changes in Response to Cyclic Hypertonic Loading Using A Novel Microfludic Device. Summer ASME 2003, Key Biscayne, Fl.
  • Chao PG, Han SH, Nicoll SB, and Hung CT (2003). ACL and MCL Fibroblast Migration in Response to an Applied DC Electric Field. Trans ORS 49, 673.
  • Chao PG, Tang Z, Angelini E, West AC, and Hung CT (2003). A novel microfluidic device to study the real-time response of cultured cells to applied dynamic osmotic loading. Trans ORS 49, 252.
  • Chao PG, Angelini E, Tang Z, Chang W, Bulinski JC, West AC, Hung CT (2002). Novel Application of Microfluidic Channels in Studying Cell Migration and Reorientation in Response to Direct Current Electric Fields. Winter ASME Conference 2002, New Orleans, LA.
  • Chao PG, Hakaka A, Nicole SB, and Hung CT (2002). Electric-Field Induced Migration and Orientation of Ligament Fibroblasts and Chondrocytes. Trans ORS 48, 582.
  • Hung CT, Jamieson KV, Roy R, Wong DD, Chao PG, Sun DDN, and Guo XE (2001). Comparison of Transient Chondrocyte Swelling and Shrinking Behavior. ORS Trans 47, 559.
  • Mauck RL, Seyhan SL, Wang CCB, Soltz MA, Chao PG, Valhmu WB, Ateshian GA, and Hung CT (2001). Physiologic Loading for Cartilage Tissue Engineering ¡V Effect of Chondrocyte Seeding Density. ORS Trans 47, 622.
  • Chao PG, Palmer GD, Valhmu WB, Thomas J, and Hung CT (2001). Characteristic Chondrocyte Response to Hyperosmotic Loading -- Influence of Medium Constituents. ORS Trans 47, 557.
  • Chao PG, Liu W, Roy R, Mauck RL, and Hung CT (2000). Cathodal Migration of Chondrocytes to Applied DC Electric Fields: Effects of Neomycin. Winter ASME Conference 2000, Orlando, Fl.
  • Valhmu WB, Palmer G, Wang CCB, Raia F, Mauck RL, Chao PG, and Hung CT (2000). Fluid Flow Modulates Aggrecan Gene Expression Through Mitogen-Activated Protein Kinase Pathway. ORS Trans 25, 82.
  • Palmer GD, Chao PG, Raia F, Mauck RL, Valhmu WB, and Hung CT (2000). Osmotic Loading Regulates Chondrocytes Cell Size and Aggrecan Gene Expression. ORS Trans 25, 924.
  • Mauck RL, Chao PG, Gilbert B, Valhmu WB, Hung CT (1999). Chondrocyte Translocation and Orientation to Applied DC Electric Fields. Winter ASME Conference, Nashville, TN.

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All Rights Reserved.  Last Update November 2017