PUBLICATIONS

Papers (*Corresponding author, **Equally contributed first author)

A. Dementia and Geriatric Epidemiologic Research

  • Asymmetric handgrip strength can predict cognitive impairment in older adults.

    Handgrip Strength Asymmetry and Cognitive Impairment Risk: Insights from a Seven-Year Prospective Cohort Study.

    Tao-Chu Peng, Jeng-Min Chiou, Yen-Ching Chen*, Jen-Hau Chen*

    Journal of Nutrition, Health and Aging 28(1): 100004 (January 2024). 
  • Olfactory dysfunction may serve as an early marker for predicting cognitive impairment in older adults.

    Association between olfactory dysfunction and cognitive impairment in dementia-free older adults: A prospective cohort study in Taiwan.

    Mu-Cyun Wang, Jeng-Min Chiou, Yen-Ching Chen*, Jen-Hau Chen*

    Journal of Alzheimer’s Disease 96(4): 2477-2488 (December 2023). 
  • Physicians’ recognition of end of life may influence patients’ good death.

    Physicians are over optimistic in recognizing inpatients’ survival and palliative care needs: A large scale multi-center study in Taiwan.

    Chaoming Huang, Sheng-Jean Huang, Tai-Yin Wu*, Yen-Ching Chen, Sheng-Huang Hsiao, Dachen Chu

    QJM: An International Journal of Medicine, hcad246 (October 2023). 
  • Repeated measures on dietary quality (3 trajectories) in relation to cognition of older adults.

    Longitudinal trajectories of dietary quality and cognitive performance in older adults: Results from a 6-year cohort study.

    Ling-Wei Chen, Yi-Chun Chou, Meei-Shyuan Lee, Jeng-Min Chiou, Jen-Hau Chen*, Yen-Ching Chen*.

    Clinical Nutrition 42(6): 879-886 (June 2023). 
  • Association between baseline retinal vascular structure and the risk of cognitive impairment over time.

    The Association between Retinal Vascular Fractal Dimension and Cognitive Function in The Community-dwelling Older Adults Cohort TIGER.

    Ting-Yu Wu, Yi-Ting Hsieh, Yu-Hsin Wang, Jeng-Min Chiou, Ta-Fu Chen, Liang-Chuan Lai, Jen-Hau Chen*, Yen-Ching Chen*.

    Journal of Formosan Medical Association 122(10): 1050-1060 (October 2023).
  • A long-term cohort study on the association of preclinical depression, sleep and cognition in community-dwelling older adults.

    Association of subclinical depressive symptoms and sleep with cognition in the community-dwelling older adults.

    Ching-Jow Hsieh, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen*, Jen-Hau Chen*.

    Journal of Formosan Medical Association 122(8): 790-799 (August 2023). 
  • First study exploring interaction of exposure to ambient air pollutants and indoor air quality on cognition of older adults (using multi-pollutant model considering collinearity among pollutants)

    Effect of indoor air quality on the association of long-term exposure to low-level air pollutants with cognition in older adults.

    Yen-Ching Chen, Pei-Iun Hsieh, Jia-Kun Chen, Emily Kuo, Hwa-Lung Yu, Jeng-Min Chiou, Jen-Hau Chen*.

    Environmental Research 233(15): 115483 (September 2023). 
  • First study on sex-specific multimorbid patterns related to cognition in Taiwanese older adults (accounting for the effect of informative dropout)

    Multimorbid patterns and cognitive performance in the presence of informative dropout among community-dwelling Taiwanese older adults.

    Pei-Iun Hsieh, Yen-Ching Chen, Jeng-Min Chiou, Jen-Hau Chen*.

    Innovation in Aging 7(2): 1-13 (February 2023).  
  • Longitudinally predicting the risk of cognitive impairment using grip strength and sarcopenia

    Grip strength and sarcopenia predict 2-year cognitive impairment in community-dwelling older adults.

    Tao-Chun Peng, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen*, Jen-Hau Chen*.

    Journal of the American Medical Directors Association 24(3): 292-298.e1 (March 2023).  
  • A review for instruments assessing the burden of dementia caregivers

    Caregiver burden and dementia: A systematic review of self-report instruments.

    Jennifer Young Tu, Grace Jin, Jen-Hau Chen*, Yen-Ching Chen*.

  • Journal of Alzheimer’s Disease 86(4):1527-1543 (March 2022). 
  • The first study exploring extended definitions of cognitive frailty combining frailty dimensions and cognitive domains

    A longitudinal study on the association of interrelated factors among frailty dimensions, cognitive domains, cognitive frailty, and all-cause mortality.

    Jen-Hau Chen, Hua-San Shih, Jennifer Tu, Jeng-Min Chiou, Shu-Hui Chang, Wei-Lie Hsu, Liang-Chuang Lai, Ta-Fuh Chen, Yen-Ching Chen*.

  • Journal of Alzheimer’s Disease 84(4): 1795-1809 (December 2021).
  • A community-based cohort study on the association between metabolic syndrome and successful aging.

    The association between metabolic syndrome and successful aging- using an extended definition of successful aging.

    Yi-Hsuan Lin, Jeng-Min Chiou, Ta-Fu Chen, Liang-Chuan Lai, Jen-Hau Chen, Yen-Ching Chen*.

    PLoS ONE 16(11): e0260550 (December 2021).


  • Long-term exposure to air pollutants (estimated by Bayesian maximum entropy) in relation to cognitive function in older adults - A prospective cohort study

    Long-term exposure to air pollutants and cognitive function in Taiwanese community-dwelling older adults: A four-year cohort study.

    Jen-Hau Chen, Tsung-Yu Kuo, Hwa-Lung Yu, Charlene Wu, Su-Ling Yeh, Jeng-Min Chiou, Ta-Fu Cheng, Yen-Ching Chen*.

    Journal of Alzheimer’s Disease 78(4):1585-1600 (December 2020).


  • The effect of chronic renal disease and cortical thinning (neurodegeneration) on cognitive function

    Impacts of Kidney Dysfunction and Cerebral Cortical Thinning on Cognitive Change in Elderly Population.

    Chih-Hao Chen, Ya-Fang Chen, Ping-Huan Tsai, Jeng-Min Chiou, Liang-Chuan Lai, Ta-Fu Chen, Hung Hung, Jen-Hau Chen*, Yen-Ching Chen*.

    Journal of Alzheimer's Disease. 76(1):225-236 (June 2020).


  • 高齡健康與長照研究中心研議計畫 政策建言書,第三篇高齡醫學研究與轉譯重要性,第三章高齡長者失能/失智之世代研究 ( 2019 財團法人國家衛生研究院論壇)

    議題委員:  劉景寬、黃宗正、王培寧、白明奇、胡朝榮、徐崇堯、郭乃文、陳人豪、陳正生、許志成、傅中玲、程 藴菁、 賴德仁


  • First study found a non-linear relationship between Retinal ganglion cell-inner plexiform layer and cognitive function in the elderly

    Retinal ganglion cell-inner plexiform layer thickness is nonlinearly associated with cognitive impairment in the community-dwelling elderly.

    Yao-Lin Liu, Yi-Ting Hsieh, Ta-Fu Chen, Jeng-Min Chiou, Min-Kuang Tsai, Jen-Hau Chen*, Yen-Ching Chen*.

    Alzheimer’s & Dementia: Diagnosis, Assessment, and Disease Monitoring. 11: 19-27 (December 2019).


  • The first paper exploring the joint effect of diet quality and vegetable variety in relation to cognitive decline in the older adults

    Association of diet quality and vegetable variety with the risk of cognitive decline in Chinese older adults.

    Yi-Chun Chou, Meei-Shyuan Lee, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen*, Jen-Hau Chen*.

    Nutrients. 2019, 11(7), 1666 (July 2019).


  • Helicobacter pylori infection increases the risk of cognitive impairment in non-demented elders

    Association between Helicobacter pylori infection and cognitive impairment in the elderly.

    Ming-Lun Han, Jen-Hau Chen, Min-Kuang Tsai, Jyh-Ming Liou, Jeng-Min Chiou, Ming-Jang Chiu, Yen-Ching Chen*.

    Journal of the Formosan Medical Association. 117(11): 994-1002 (November 2018).


  • The socioeconomic status affects the association between lifestyle and cognitive function in the elderly

    The effect of lifestyle on late-life cognitive change under different socioeconomic status.

    Pei-Hsuan Weng, Jen-Hau Chen, Jeng-Min Chiou, Yu-Kang Tu, Ta-Fu Chen, Ming-Jang Chiu, Sung-Chun Tang, Shin-Joe Yeh, Yen-Ching Chen*.

    PLoS ONE. 13(6): e0197676 (June 2018).
    ASPPH Friday News


  • Chronic kidney disease is associated with cerebral cortical thinning (indicator of neurodegeneration in the preclinical phase of dementia) in the elderly

    Effect of kidney dysfunction on cerebral cortical thinning in elderly population.

    Chih-Hao Chen, Ya-Fang Chen, Ming-Jang Chiu, Ta-Fu Chen, Ping-Huan Tsai, Jen-Hau Chen, Chung-Jen Yen, Sung-Chun Tang, Shin-Joe Yeh, Yen-Ching Chen*.

    Scientific Reports 7, Article number: 2337 (May 2017).


  • The first study identified Chinese-specific dietary patterns related to cognitive function in the preclinical phase

    Association of dietary patterns with global and domain‐specific cognitive decline in Chinese elderly.

    Yen-Ching Chen*, Chien-Cheng Jung, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, Meei-Shyuan Lee.

    Journal of the American Geriatrics Society 65(6):1159-1167 (June 2017)
    ASPPH Friday News


  • The first genome-wide association study (GWAS) of late-onset Alzheimer’s disease (LOAD) in Chinese elderly: Using performance metrics to identify genetic markers for LOAD

    Performance metrics for selecting genetic polymorphisms in late-onset Alzheimer's disease.

    Yen-Ching Chen*, Chi-Jung Hsiao, Chien-Cheng Jung, Hui-Han Hu, Jen-Hau Chen, Wen-Chung Lee, Jeng-Min Chiou, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Chien-Jen Chen*, Hwai-I Yang*.

    Scientific Reports 6, Article number: 36155 (November 2016).
    ASPPH Friday News


  • Interactions among polymorphisms of CHRNA7, APOE e4 status and smoking status on the risk of dementia

    CHRNA7 polymorphisms and dementia risk: Interactions with apolipoprotein ε4 and cigarette smoking.

    Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.

    Scientific Reports 6, Article number: 27231 (June 2016).
    ASPPH Friday News


  • Simultaneous test of the lipid metabolism-related gene SAR1B and APOE ε4 significantly increase the sensitivity of screening late-onset Alzheimer’s disease

    Genetic polymorphisms of lipid metabolism gene SAR1 homolog B and the risk of Alzheimer’s disease and vascular dementia.

    Jen-Hau Chen, Ching-Jow Hsieh, Yi-Ling Huang, Yen-Ching Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu.

    Journal of the Formosan Medical Association. 115:38-44 (January 2016).


  • 第三部分:失智症研究中的遺傳流行病學研究 “Dementia and principles of care” Wen-Chen Ouyang (Editor).

    Yen-Ching Chen

    Taiwanese Society Of Gariatric Psychiatry Taichung, Taiwan. (2015) p.97-101. ISBN: 978-986-90-0401-5 (Book chapter)


  • The first study explored the association of air pollutants (PM10 and O3) with the risk of clinically-diagnosed Alzheimer’s disease and vascular dementia

    Special Invited Article: Association between air pollutants and dementia risk in the elderly.

    Yun-Chun Wu, Yuan-Chien Lin, Hwa-Lung Yu, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.

    Alzheimer’s & Dementia: Diagnosis, Assessment, and Disease Monitoring 1(2): 220-228 (May 2015).

    台灣臨床失智症學會 財團法人立夫醫藥研究文教基金會學術獎
    ASPPH Friday News
    National Taiwan University, press release: Air pollutants(PM10) and ozone increase the risk of dementia)


  • The association between religious affiliation and the risk of Alzheimer’s disease in the elderly

    Religious affiliation and the risk of dementia in Taiwanese elderly.

    Kun-Pei Lin, Yi-Chun Chou, Jen-Hau Chen, Chi-Dan Chen, Sheng-Ying Yang, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.

    Archives of Gerontology and Geriatrics 60(3): 501-6 (May-Jun 2015).


  • Association of three types of leisure activities, APOE ε4 status and the risk of dementia in the elderly

    Leisure activities, apolipoprotein E e4 status, and the risk of dementia.

    Sheng-Ying Yang, Pei-Hsuan Weng, Jen-Hau Chen, Jeng-Min Chiou, Chih-Yin Lew-Ting, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.

    Journal of the Formosan Medical Association. 114:1216-1224 (December 2015).


  • Fist study explored the association between aging gene CISD2 and the risk of late-onset Alzheimer’s disease

    Sequence variants of the aging gene CISD2 and the risk of Alzheimer’s disease.

    Ching-Jow Hsieh, Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yiph, Yi-Min Chu, Yen-Ching Chen*.

    Journal of the Formosan Medical Association. 114 (7): 627-632 (July 2015).


  • Dementia: A Focused Review.

    Ka-Ian Leong, Yen-Ching Chen, Jen-Hau Chen

    Journal of Internal Medicine of Taiwan. 25: 151-157 (July 2014).


  • CHRNA7 polymorphisms and response to cholinesterase inhibitors in Alzheimer’s disease.

    Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.

    PLoS ONE 8(12): e84059 (December 2013).

    Merck Sharp & Dohme Excellent Thesis Award, Taiwan Geriatrics Society


  • Sequence variants of toll-like receptor 4 and late-onset Alzheimer’s disease.

    Yen-Ching Chen*, Ping-Keung Yip, Yi-Ling Huang, Yu Sun, Li-Li Wen, Yi-Min Chu, Ta-Fu Chen.

    PLoS ONE 7 (12): e50771 (December 2012).


  • Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease.

    Shih-Yuan Chen, Ta-Fu Chen, Liang-Chuan Lai, Jen-Hau Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*.

    Journal of Neuroinflammation 9:21 (January 2012).


  • Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease.

    Hui-Chi Cheng, Yu Sun, Liang-Chuan Lai, Shih-Yuan Chen, Wen-Chung Lee, Jen-Hau Chen, Ta-Fu Chen, Hua-Hsiang Chen, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Wei J. Chen, Yen-Ching Chen*.

    Journal of Negative Results in Biomedicine 11:5 (January 2012).


  • Genetic polymorphisms of clusterin (CLU) gene are associated with a decreased risk of Alzheimer’s disease.

    Yen-Ling Lin, Shih-Yuan Chen, Liang-Chuan Lai, Jen-Hau Chen, Shi-Yi-Yang, Yi-Ling Huang, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Wei J. Chen, Yen-Ching Chen*.

    European Journal of Epidemiology 27(1):73-75 (January 2012).


  • Genetic testing for prediction of Alzheimer's disease in the elderly.

    Yen-Ching Chen, Jen-Hau Chen.

    Health World 432: 26-27 (December 2011).


  • Genetic polymorphisms of a novel vascular susceptibility gene, ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer’s disease.

    Kun-Pei Lin, Shih-Yuan Chen, Liang-Chuan Lai, Yi-Ling Huang, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Wei J. Chen, Yen-Ching Chen*.

    PLoS ONE 6(6): e20573 (June 2011).

    Outstanding Master Thesis Award, Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association 2011 Joint Annual Meeting and Symposium


  • Body mass index at early age and the risk of dementia.

    Yen-Ching Chen, Ta-Fu Chen, Ping-Keung Yip, Chi-Yin Hu, Yi-Min Chu, Jen-Hau Chen.

    Archives of Gerontology and Geriatrics 50 Suppl 1:S48-52 (February 2010).


  • Risk factors for dementia.

    Jen-Hau Chen, Kun-Pei Lin, Yen-Ching Chen*.

    Journal of the Formosan Medical Association. 108(10): 754-764 (October 2009).


  • Occurrence and treatment of suspected pneumonia in long-term care residents dying with advanced dementia.

    Jen-Hau Chen, Jennifer L. Lamberg, Yen-Ching Chen, Dan K. Kiely, John H. Page, Carmel J. Person, Susan L. Mitchell.

    Journal of the American Geriatrics Society 54(2): 290-295 (February 2006).


  • B. Osteoporosis Epidemiologic Research


    C. Prostate Cancer Epidemiologic Research

    D. Arsenic Exposure and Cancer Epidemiologic Research

    E. Other Cancer Epidemiologic Research

    F. Other Research

    Conferences

    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association, Indoor Air Quality of Taiwan 2019 Joint Annual Meeting and Symposium (Sep. 26-28, 2019, Taipei, Taiwan)

      Poster: Min-Kuang Tsai, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen. Association of physical activity, gait speed and cognitive function in non-demented elderly cohort in the community.


    • Alzheimer’s Association International Conference (AAIC) 2019 (July 14-18, 2019, Los Angeles, CA, USA)

      Oral presentation: I-Wen Chen, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen (presenter). Association between the Olfactory Identification Ability and Cognitive Function in Non-Demented Elderly.

      Poster: Tao-Chun Peng, Yen-Ching Chen, Ta-Fu Chen, Jeng-Min Chiou, Jen-Hau Chen. Association between Sarcopenia and Cognitive Impairment in Community-Dwelling Older Adults.

      Poster: Yi-Chieh Chen, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Yen-Ching Chen. The Association between Stressful Life Events and Cognitive Performance in the Community-Dwelling Elderly.


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association, Taiwan Cancer Registry, Taiwan Health Insurance Association 2018 Joint Annual Meeting and Symposium (Oct. 13-14, 2018, Taichung, Taiwan)

      Invited speaker: Symposium of Taiwan Epidemiology Association, 2018


    • Taiwan Association of Gerontology and Geriatrics (Jun. 10, 2018, Taipei, Taiwan)

      Oral presentation: Yao-Lin Liu, Yi-Ting Hsieh, Ta-Fu Chen, Jeng-Min Chiou, Min-Kuang Tsai, Yen-Ching Chen, Jen-Hau Chen (presenter). Macular ganglion cell-inner plexiform layer (GC-IPL) thickness: a potential biomarker in cognitive impairment in the community-dwelling elderly.


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association, Taiwan Cancer Registry, Indoor Air Quality of Taiwan 2017 Joint Annual Meeting and Symposium(Oct. 28-29, 2017, Kaohsiung, Taiwan) –Sustainable development and public health

      Oral presentation: Yen-Ching Chen, Chien-Cheng Jung, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, and Meei-Shyuan Lee. Association of Dietary Patterns with Global and Domain-Specific Cognitive Decline in Chinese Elderly.

      Oral presentation: Chih-Hao Chen, Ya-Fang Chen, Ming-Jang Chiu, Ta-Fu Chen, Ping-Huan Tsai, Jen-Hau Chen, Chung-Jen Yen, Sung-Chun Tang, Shin-Joe Yeh, and Yen-Ching Chen. Effect of kidney dysfunction on cerebral cortical thinning in elderly population.

      Oral presentation: Min-Kuang Tsai, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, and Yen-Ching Chen. The Association of Physical Activity, self-reported sleep disturbances with Cognitive Decline.

      Oral presentation: Shu-Mei Yang, Shao-Chi Chu, Jen-Hau Chen, Ta-Fu Chen, Ping-Keung Yip, Yi-Min Chu, Sun Yu, Li-Li Wen, and Yen-Ching Chen. Consumption of coffee or tea, vascular risk factors and the risk of dementia in the elderly.


    • Alzheimer’s Association International Conference (AAIC) 2017 ( July 16-20, 2017, London, England)

      Poster: Shu-Mei Yang, Yuan-Chien Lin, Hwa-Lung Yu, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Ping-Keung Yip, Yen-Ching Chen. Association between PM10 exposure, coffee or tea consumption, and dementia risk in the elderly.

      Poster: Min-Kuang Tsai, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, Ming-Jang Chiu, Yen-Ching Chen. Self-reported sleep disturbances and cognitive decline in the elderly- Attenuating the risk by physical activity.

      Poster: Chih-Hao Chen, Ya-Fang Chen, Ming-Jang Chiu, Ta-Fu Chen, Ping-Huan Tsai, Jen-Hau Chen, Chung-Jen Yen, Sung-Chun Tang, Shin-Joe Yeh, Yen-Ching Chen. Effect of kidney dysfunction on cerebral cortical thinning in elderly population.

      Poster: Yi-chun Chou, Jen-Hau Chen, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, Meei-Shyuan Lee, Yen-Ching Chen. Diet quality, vegetable variety and risk of cognitive decline in Chinese elderly.


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association, Taiwan Cancer Registry, Indoor Air Quality of Taiwan 2016 Joint Annual Meeting and Symposium (Oct. 15-16, 2016, Taipei, Taiwan)–Invest healthier future – healthy people, healthy citizen

      Oral presentation: Chien-Cheng Jung, Yuan-Chien Lin, Hwa-Lung Yu, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Ping-Keung Yip, Yen-Ching Chen. Association between PM10 exposure, vascular risk factors, and dementia risk in the elderly.

      Oral presentation: Min-Kuang Tsai, Chien-Cheng Jung, Jen-Han Chen, Jeng-Min Chiou, Ta-Fu Chen, Ming-Jang Chiu, Yen-Ching Chen. The association between physical activity and cognitive decline by APOE ε4 status in the elderly.


    • Alzheimer’s Association International Conference (AAIC) 2016 ( July 24-28, 2016, Toronto, Canada)

      Poster: Jen-Hau Chen, Chien-Cheng Jung, Meei-Shyuan Lee, Min-Kuang Tsai, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, Ming-Jang Chiu, Yen-Ching Chen. Chinese dietary patterns and domain-specific cognitive decline in the elderly.

      Poster: Chien-Cheng Jung, Shao-Chi Chu, Jen-Hau Chen, Ta-Fu Chen, Ping-Keung Yip, Yi-Min Chu, Sun Yu, Li-Li Wen, Yen-Ching Chen. Consumption of coffee or tea, vascular risk factors and the risk of dementia in the elderly.

      Poster: Min-Kuang Tsai, Jen-Han Chen, Chien-Cheng Jung, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, Ming-Jang Chiu, Yen-Ching Chen. Physical activity, potential confounders and cognitive decline in the elderly.

      Poster: Yen-Ching Chen, Chi-Jung Hsiao, Chien-Cheng Jung, Hui-Han Hu, Jen-Hau Chen, Wen-Chung Lee, Jeng-Min Chiou, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Chien-Jen Chen, Hwai-I Yang. Application of clinical-based indices on identification of genetic markers for Late-onset Alzheimer’s Disease.


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association, Taiwan Cancer Registry, Indoor Air Quality of Taiwan 2015 Joint Annual Meeting and Symposium (Oct. 17-18, 2015, Taipei, Taiwan) – Health in All Policies

      Oral presentation: Ming-Luan Han, Jen-Hau Chen, Jyh-Ming Liou, Ta-Fu Chen, Yen-Ching Chen. Association between H. Pylori infection and cognition in the elderly.

      Oral presentation: Yu-Chun Tsai, Jen-Hau Chen, Ta-Fu Chen, Yen-Ching Chen. Association between physical activities and cognition in Taiwanese elderly.


    • The 3rd Emerging Information and Technology Association (EITA)-Bio Conference, Taipei, Taiwan (October 24-25, 2015)

      Workshop: Machine learning and big data, biostatistics, in silico research and biomedical informatics.

      Invited speaker: Genetic Association Studies on Alzheimer’s Disease in Taiwan Elderly.


    • Alzheimer’s Association International Conference (AAIC) 2015 (July 18-23, 2015, Washington, D.C., USA)

      Poster: Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen. Interactions between APOE ε4 status and hypercholesteremia on response to acetylcholinesterase inhibitor in Alzheimer’s disease.

      Poster: Kai-Ting Chang, Jen-Hau Chen, Meei-Shyuan Lee, Jeng-Min Chiou, Ta-Fu Chen, Ya-Fang Chen, Sung-Chun Tang, Shin-Joe Yeh, Yen-Ching Chen. Association between dietary patterns and cognitive impairment in the elderly.

      Poster: Ming-Lun Han, Jen-Hau Chen, Ta-Fu Chen, Yen-Ching Chen. Relationship between Helicobacter pylori infection and cognitive performance in the elders.


    • Symposium on Brain and Nutrition, 2014 International Conference of Korean Nutrition Society, Jeju, Korea (November 5-11, 2014, Jeju, Korea)

      Session: Dietary pattern and cognitive function in the elderly.

      Invited speaker: Association between dietary pattern and cognitive function in the elderly.


    • Alzheimer’s Association International Conference (AAIC) 2014 (July 12-17, 2014, Copenhagen, Denmark)

      Poster: Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Ping-Keung Yip, Yen-Ching Chen. Caffeine intake and cognitive response to acetylcholinesterase inhibitors in Alzheimer’s disease.

      Poster: Jen-Hau Chen, Ching-Jow Hsieh, Yi-Ling Huang, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen. Genetic polymorphisms of lipid metabolism gene SAR1 homolog B and the risk of Alzheimer’s disease and vascular dementia.

      Poster: Yun Chun Wu, Yuan-Chien Lin, Hwa-Lung Yu, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen. The spatial relationship between air pollutants and the risk of dementia.


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association, Taiwan Cancer Registry, Indoor Air Quality of Taiwan 2013 Joint Annual Meeting and Symposium (Oct. 19-20, 2013, Taipei, Taiwan) – Integration of Health and Well-being Chair of symposium on “ Research and Challenges of Common Disease in the Elderly”

      Poster: Pei-Sung Hsu, Mei-Hsuan Lee, Jeng-Min Chiou, Jen-Hau Chen, Keh-Sung Tsai, Yen-Ching Chen. Association of dietary pattern and bone mineral density in Taiwanese. women.


    • Taiwan Osteoporosis Association 2013 Annual Meeting (August 25, 2013, Taipei, Taiwan)

      Poster: Ying-Shu You, Ching-Yu Lin, Keh-Sung Tsai, Jeng-Min Chiou, Yen-Ching Chen, Chwen-Keng Tsao, Jen-Hau Chen. Association between metabolome and bone mineral density in Taiwanese women.


    • 28th International Conference of Alzheimer’s Disease International(April 18-20, 2013, Taipei, Taiwan) – Dementia: Action for global change

      Oral presentation: The association between cognitive function and fall risk in the elderly. (Presenter: Helen Fu)

      Oral presentation: Meta-Analysis: smoking as a risk factor for Alzheimer’s disease and vascular dementia. (Presenter: Dr. Pei-Hsuan Weng)


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association 2012 Joint Annual Meeting and Symposium (Oct. 6-7, 2012, Taichung, Taiwan) – Aging Society: Challenges that Public Health Face

      Chair of symposium on “Dementia Research and Challenges”

      Oral presentation: Cigarette smoking, genotype of apolipoprotein e4 and the risk of Alzheimer’s disease. (Presenter: Dr. Wan-Ching Liao)

      Oral presentation: Association between age of menopause, genetic polymorphisms of lipid metabolism-related genes, and the risk of late-onset Alzheimer’s disease. (Presenter: Dr. Jui-Wen Fang)


    • Alzheimer’s Association International Conference (July 14-19, 2012, Vancouver, British Columbia, Canada)

      Poster: Chia-Chih Tsai, Jen-Hau Chen, Ping-Keung Yip, Ta-Fu Chen, Yu Sun, Li-Li Wen, Yi-Min Chu, Yen-Ching Chen*. Effect modification by APOE e4 status on the association of potential confounders and the risk of Alzheimer's disease.

      Poster: Jen-Hau Chen, Shen-Yin Yang, Shih-Yuan Chen, Ping-Keung Yip, Ta-Fu Chen, Yu Sun, Li-Li Wen, Yi-Min Chu, Yen-Ching Chen*. Leisure activities, APOE e4 status, and Alzheimer's disease.

      Poster: Shih-Yuan Chen, Jen-Hau Chen, Hua-Hsiang Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*. Sequence variants of toll-like receptor 4 (TLR4) gene and the risk of Alzheimer's disease.


    • Osteoporosis and Bone Conference 2012 (July 1-4, 2012, Manchester, UK)

      Poster: Yue-Yuan Lee, Yen-Ching Chen, Jeng-Min Chiou, Keh-Sung Tsai, Jen-Hau Chen*. Associations between metabolic syndrome, menopausal status and low bone mineral density in Taiwanese women.

      Poster: Yueh-Hsuan Sheng, Jen-Hau Chen, Jeng-Min Chiou, Keh-Sung Tsai, Yue-Yuan Lee, Yen-Ching Chen*. Association of lipid prfoile, menopausal status with bone mineral density in Taiwanese women.


    • Symposium on Challenges in the Analysis of -omics Data (March 30, 2012, Taipei, Taiwan) Coordinator and Master of ceremony.

      Poster: Chien-Lin Mao, Jeng-Min Chiou, Jen-Hau Chen, Yen-Ching Chen*. Association of SPP1 polymorphisms and bone mineral density.


    • Taiwan Association of Obstetrics and Gynecology (March 3-4, 2012, Taipei, Taiwan)

      Poster: Yue-Yuan Lee, Jen-Hau Chen, Keh-Sung Tsai, Jeng-Min Chiou, Yen-Ching Chen*. Association between menopausal status and metabolic syndrome in Taiwanese women.


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association 2011 Joint Annual Meeting and Symposium (Oct. 15-16, 2011, Taipei, Taiwan)

      Best Master Thesis Award: Genetic polymorphisms of a novel vascular susceptibility gene, ninjurin2 (NINJ2), are associated with a decreased risk of Alzheimer's disease (Awardee: Dr. Kun-Pei Lin)

      Chair of Symposium on “Aging Epidemiology”

      Oral presentation: Genetic polymorphisms ofinterleukin-6 (IL-6) are associated with risk of Alzheimer's disease. (Presenter: Dr. Shih-Yuan Chen)

      Oral presentation: Genetic polymorphisms of CHRNA7 Gene and the risk of Alzheimer's disease. (Presenter: Dr. Pei-Hsuan Weng)

      Oral presentation: The risk factors for the aging males' symptoms. (Presenter: Dr. I-Ching Lee)

      Oral presentation: Association between metabolic syndrome and change of bone mineral density in Taiwanese women. (Presenter: Dr. Yue-Yuan Lee)

      Oral presentation: Secreted phosphoprotein-1 (SPP1) polymorphisms were associated with bone mineral density change rate in Taiwanese women. (Presenter: Chien-Lin Mao)


    • Taiwan Association of Geriatrics and Gerontology (June 5, 2011, Taipei, Taiwan)

      Poster: Weng PH, Chen JH, Chen HH, Chen SY, Chen TF, Sun Yu, Yip PK, Li-Li Wen LL, Yi-Min Chu, Yen-Ching Chen*. Interactions between APOE genotype and hypercholesteremia modify the response to acetylcholinesterase inhibitor in Alzheimer’s disease.


    • Alzheimer’s Association International Conference on Alzheimer’s Disease (AAICAD), (July 16-21, 2011, Paris, France)

      Poster: Pei-Hsuan Weng, Jen-Hau Chen, Shih-Yuan Chen, Hua-Hsiang Chen, Ta-Fu Chen, Yu Sun, Ping-Keung Yip, Li-Li Wen, Yi-Min Chu, Yen-Ching Chen*. Baseline cognition and education level as predictors for response to acetylcholinesterase inhibitor in Alzheimer’s disease.

      Poster: Ming-Shan Huang, Yi-Ling Huang, Jen-Hau Chen, Ying-Ping Chen, Yen-Ling Lin, Hui-Chi Cheng, Kun-Pei Lin, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*. Evaluating epistatic interactions in Alzheimer's disease using multifactor dimensionality reduction and entropy-based estimation.

      Poster: Ching-Jow Hsieh, Shih-Yuan Chen, Jen-Hau Chen, Hua-Hsiang Chen, Ta-Fu Chen, Yu Sun, Ping-Keung Yip, Li-Li Wen, Yi-Min Chu, Yen-Ching Chen*. Sequence variants of CISD2 gene and the risk of Alzheimer’s disease.

      Poster: Shih-Yuan Chen, Jen-Hau Chen,, Hua-Hsiang Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Chen*. Sequence variants of interleukin 6 (IL-6) gene and the risk of Alzheimer’s disease.


    • The 102nd American Association for Cancer Research Annual Meeting (April 2-6, 2011, Orlando, FL, USA) ]

      Poster: Yi-Ling Huang, John H. Page, Jen-Hau Chen, Shih-Yuan Chen, Yen-Ling Lin, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, John S. Witte, Yen-Ching Chen*. Genetic polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: A systematic review and meta-analysis.


    • Taiwan Public Health Association, Taiwan Epidemiology Association, Taiwanese Injury Prevention & Safety Promotion Association 2010 Joint Annual Meeting and Symposium (Oct. 2-3, 2010, Taipei, Taiwan)

      Chair of Symposium on “Dementia Epidemiology”

      Oral presentation: Genetic polymorphisms of clusterin (CLU) gene and the risk of Alzheimer's disease. (Presenter: Yen-Ling Lin)

      Oral presentation: Genetic polymorphisms of nerve growth factor receptor (NGFR) gene and the risk of Alzheimer's disease. (Presenter: Hui-Chi Cheng)

      Oral presentation: Genetic polymorphisms of ninjurin2 (NINJ2) gene and the risk of dementia. (Presenter: Dr. Kun-Pei Lin)

      Oral presentation: Association between leisure activity and the risk of dementia. (Presenter: Sheng-Ying Yang)


    • 2010 American Geriatric Society Annual Scientific Meeting (May 12-15, 2010, Orlando, FL, USA)

      Poster: Jen-Hau Chen, Yi-Ling Huang, Ta-Fu Chen, Ping-Keung Yip, Chi-Yin Hu, Yi-Min Chu, Yen-Ching Chen. BMI at different ages, BMI changes and risk of Alzheimer's disease and vascular dementia.


    • The 101st American Association for Cancer Research Annual Meeting (April 17-21, 2010, Washington DC, USA)

      Poster: Yen-Ching Chen, Yi-Ling Huang, Elizabeth A. Platz, Lu Zheng, John F. Alderete, Edward Giovannucci, Siobhan Sutcliffe. Toll-like receptor 4 polymorphisms modify the association between T. vaginalis serostatus and prostate cancer risk.


    • The 41st Asia-Pacific-Academic Consortium for Public Health (APACPH) Conference (Dec. 3-6, 2009, Taipei, Taiwan)

      Oral presentation: Kun-Pei Lin, Jen-Hau Chen, Ta-Fu Chen, Ping-Keung Yip, Chen-Shuo Hong Chi-Yin Hu, Yen-Ching Chen. Association between religion and dementia. (Presenter: Dr. Kun-Pei Lin)

      Poster: Yen-Ching Chen, Jen-Hau Chen, Ta-Fu Chen, Ping-Keung Yip, Chi-Yin Hu. Association between body mass index at different age and the risk of dementia.

      Oral presentation: Yen-Ling Lin, Jen-Hau Chen, Ta-Fu Chen, Ping-Keung Yip, Yen-Ching Chen. Cigarette smoke affected the association between type 2 diabetes mellitus and the risk of dementia. (Presenter: Yen-Ling Lin)

      Poster: Hui-Chi Cheng, Jen-Hau Chen, Ta-Fu Chen, Ping-Keung Yip, Yen-Ching Chen. Interaction between type 2 diabetes mellitus and the consumption of tea or coffee on the risk of dementia.

      Oral presentation: Ching-Jow Hsieh, Yen-Ching Chen, Mei-Shu Lai, Chen-Jee Hong, Kuo-Liong Chien. Association study of serotonin receptor and transporter polymorphisms with tardive dyskinesia in chronic schizophrenia. (Dr. Ching-Jow Hsieh)


    • The 100th American Association for Cancer Research Annual Meeting (April 18-22, 2009, Denver, CO, USA).

      Poster: Pei-Chun Chen, Yen-Ching Chen, Liang-Chuan Lai , Mong-Hsun Tsai, Shin-Kuang Chen, Pei-Wen Yang, Yung-Chie Lee, Jang-Ming Lee, Eric Y. Chuang Identification of novel susceptibility loci for predicting concurrent chemoradiotherapy response in esophageal cancer using a two-stage genome-wide association approach.

      Poster: Tzu-Pin Lu, Jang-Ming Lee, Chung-Ping Hsu, Chao-Jun Lin, Shin-Kuang Chen, Chiung-Ying Fang, Hung-I Harry Chen, Chien-Hung Kuo, Pei-Chun Chen, Yen-Ching Chen, Mong-Hsun Tsai, Eric Y Chuang, Liang-Chuan Lai. Genome-wide screening of genomic alterations and transcriptional modulation in non-smoking female lung cancer in Taiwan.


    • The 23rd International Society for Biological Therapy of Cancer (iSBTc) Annual Meeting and Associated Programs (October 29- November 2, 2008, San Diego, CA, USA)

      Co-Chair & invited speaker of Workshop on “Cancer inflammation: Promise for biological therapy”, Science Session Genetic polymorphisms and factors which modulate inflammation and cancer.


    • American Association for Cancer Research Special Conference: The Role of Telomeres and Telomerase in Cancer Research, American Association for Cancer Research (December 6-9, 2007, San Francisco, CA, USA)

      Poster: Yen-Ching Chen, Edward Giovannucci, Peter Kraft, David J. Hunter. Sequence variants of elaC homolog 2 (E. coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up Study.


    • The 5th International Conference on Frontiers in Cancer Prevention Research, American Association for Cancer Research (Nov. 12-15, 2006, Boston, MA, USA)

      Poster: Yen-Ching Chen, Edward Giovannucci, Peter Kraft, David J. Hunter. Association between genetic polymorphisms of macrophage scavenger receptor 1 (MSR1) gene and risk of prostate cancer in the Health Professionals Follow-Up Study.


    • The 97th American Association for Cancer Research Annual Meeting (April 1-5, 2006, Washington DC, USA).

      Poster: Yen-Ching Chen, Edward Giovannucci, Peter Kraft, Ross Lazarus, David J. Hunter. Association between toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and susceptibility to prostate cancer in the Health Professionals Follow-Up Study.


    • Poster and Exhibit Day, Harvard School of Public Health (March 31, 2005, Boston, MA, USA)

      Invited poster: Yen-Ching Chen, Edward Giovannucci, Peter Kraft, David J. Hunter. Sequence variants of toll-like receptor 4 (TLR4) and susceptibility to prostate cancer.


    • The 2nd Annual Center for Environmental Health Sciences (CEHS) Poster Session, Massachusetts Institute of Technology (MIT) (February 25, 2005, Cambridge, MA, USA)

      Invited poster: Yen-Ching Chen, Edward Giovannucci, Peter Kraft, David J. Hunter. Sequence variants of toll-like receptor 4 (TLR4) and susceptibility to prostate cancer.


    • The Oncogenomics 2005: Dissecting Cancer through Genome Research, American Association for Cancer Research (February 2-6, 2005, San Diego, CA, USA)

      Award-winning poster: Yen-Ching Chen, Edward Giovannucci, Peter Kraft, David J. Hunter. Sequence variants of toll-like receptor 4 (TLR4) and susceptibility to prostate cancer.


    • The 12th Conference of the International Society of Exposure Analysis (ISEA) and the 14th International Society for Environmental Epidemiology (ISEA/ISEE)-2002 Conference (August 11-15, 2002, Vancouer, BC, Canada)

      Poster: Yen-Ching Chen, Chitra J. Amarasiriwardena, Yu-Mei Hsueh, David C. Christiani. Stability of arsenic species and insoluble arsenic in human urine.

      Oral Presentation: Yen-Ching Chen, Huey-Jen Jenny Su, Yu-Liang Leon Guo, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee, David C. Christiani. Arsenic methylation and bladder cancer risk.

      Invited Chair of the oral section "Environmental and occupational risk factors for cancer".


    • The Superfund Basic Research Program (SBRP) Annual Meeting, NIH (Dec. 12-14, 2000, Chapel Hill, NC)

      Poster: Yen-Ching Chen, Yu-Liang Leon Guo, Huey-Jen Jenny Su, Meei-Shyuan Lee, Yu-Mei Hsueh, David C. Christiani. The association between arsenic methylation ability and the risk of skin cancer in southwestern Taiwan.


    • The 12th International Society for Environmental Epidemiology (ISEE) Conference (August 19-23, 2000, Buffalo, NY)

      Contributed Paper: Yen-Ching Chen, Meei-Shyuan Lee, Huie-Jen Su, Yu-Lian Guo, Yu-Mei Hsueh, David C. Christiani. The association between arsenic methylation ability and the risk of bladder cancer in blackfoot disease endemic area in Taiwan.


    • The 4th International Conference on Arsenic Exposure and Health Effects, Society of Environmental Geochemistry and Health (SEGH) (June 19-22, 2000, San Diego, CA)

      Poster: Yen-Ching Chen, Chitra Amarasiriwardena, Nicola Lupoli, Davdi C. Christiani. Speciation of arsenic species in urine by using HPLC-ICP-MS – Stability and transformation of arsenic species.