台大植病系
Faculty & Research >Faculty Profiles >Dr. Yeh, Hsin-Hung
Faculty Profiles
 

Dr. Yeh, Hsin-Hung

Title : Associate Professor
Highest degree : PhD. Plant Pathology, University of California at Davis, USA
Specialties : Plant virology; Plant pathology
E-mail : hyeh@ntu.edu.tw
Office : Room 221, The First Hall
Telephone : 886-2-3366 4601
FAX : 886-2-2363-6490

Plant Viral Diseases Laboratory
Positions
2002 -current Assistant Professor, Dept of Plant Pathology and Microbiology, National Taiwan University.
2001-2002 Assistant Professor, Division of Biotechnology, Dept. of Chemical Engineering, Southern Taiwan University of Technology.
 
Honors and Awards
   
Research Interests
    The interests of my lab are mainly focused on studying plant virology.  Our efforts include collection of economically important plant viruses from field, develop diagnosis methods for viral disease, study virus-plant interactions, and establish viral vector(s) for research tools. A multidisciplinary approach including genetics, molecular biology, biochemistry and functional genomics have been established and applied in our lab.
 
Lab Members

Publications (*Corresponding author)
  1. Chen, J.C.  Lu, H.C., Chen, C.E., Hsu, H.F., Chen, H.H., and Yeh, H.H. * (2013).The NPR1 ortholog PhaNPR1 is required for the induction of PhaPR1 in Phalaenopsis aphrodite. Botanical Studies 54: 31.
  2. Hsieh, M.H., Pan, Z.J., Lai, P.H., Lu, H.C., Yeh, H.H., Hsu, C.C., Wu, W.L., Chung, M.C., Wang, S.S., Chen, W.H., and Chen, H.H. (2013). Virus-induced gene silencing unravels multiple transcription factors involved in floral growth and development in Phalaenopsis orchids. Journal of Experimental Botany 64:3869–3884.
  3. Wang, H.I., Chang, C.H., Lin, P.H., Fu, H.C., Tang, C.Y., and Yeh, H.H. * (2013). Motif-based analysis reveals that recombination has been involved in the genome evolution of the multipartite viruses, Banana bunchy top virus. PLos One 8:e71565.
  4. Chen, C.E., Yeh, K.C., Wu, S.H. Wang, H.I., and Yeh, H.H. * (2013). A vicilin-like seed storage protein, PAP85, is involved in Tobacco mosaic virus replication. Journal of Virology 87: 6888-6890..
  5. Hsieh, M.H., Lu, H.C., Pan, Z.J., Yeh, H.H., Wang, S.S., Chen, W.H., and Chen, H.H. (2012). Optimizing virus-induced gene silencing efficiency with Cymbidium mosaic virus in Phalaenopsis flower. Plant Science DOI: doi:10.1016/ j.plantsci.2012.11.00.
  6. Chang, C.H., Wang, H.I., Lu, H.C., Chen, C.C., Chen, H.H., Yeh, H.H.*., and Tang, C.Y. (2012). An efficient RNA interference screening strategy for gene functional analysis. BMC Genomics 13:491. (doi:10.1186/1471-2164-13-491).
  7. Lu, H.C., Hsieh, M.H., Chen, H,H., Wang, H.I., and Yeh, H.H.* (2012). A high-throughput virus-induced gene-silencing vector for screening transcription factors in virus-induced plant defense response. Molecular Plant-Microbe Interactions 25: 738-746.
  8. Fu, S.F., Tsai, T.M., Chen, Y.R., Liu, C.P., Hais, L.J., Syue, L.H., Yeh, H.H., and Huang, H.J. (2012). Characterization of the early response of the orchid, Phalaenopsis amabilis, to Erwinia chrysanthemi infection using expression profiling. Physiologia Plantarum 145: 406–425.
  9. Lu, H.C., Chen, C.N., Tsai, M.H., Wang, H.J. Ph. D. candidate; Su, H.J., and Yeh, H.H.* (2009). Cymbidium mosaic potexvirus isolate-dependent host movement systems reveal two movement control determinants and the coat protein is the dominant. Virology 388: 147-159.
  10. Fu, H.C., HU, J.M., Hung, T.H., Su, H.J., and Yeh, H.H.* (2009). Unusual events involved in Banana bunchy top virus strain evolution. Phytopathology 99:812-822.
  11. Wang, J., Yeh, H.H. and Falk, B.W. (2009). Cis-preferential replication of Lettuce infectious yellows virus (LIYV) RNA 1: the initial step in the asynchronous replication of the LIYV genomic RNAs. Virology 386: 217-223.
  12. Chou, C.N., Chen, C.E., Wu, G.E., M.L., Su, H.J. and Yeh, H.H.* (2009). Biological and molecular characterization of Taiwanese isolates of Cucumber mosaic virus associated with banana mosaic disease. Journal of Phytopathology 157, 85-93.
  13. Lu, H.C., Chen, H.H., Tsai, W.C., Chen, W.H., Su, H.J, Chang, D.C. and Yeh, H.H*. (2007). Strategies for functional validation of genes involved in reproductive stages of orchids. Plant Physiology, 143: 558-569.
  14. Hu, J.M., Fu, H.C., Lin, C.H., Su, H.J., and Yeh, H.H*. (2007). Evidence of reassortment and concerted evolution in Banana bunchy top virus genomes. Journal of Virology. 81: 1746-1761.
  15. Medina, V., Sudarshana, M.R., Tian, T., Ralston, T.K. Yeh, H.H., and Falk, B.W. (2005). The Lettuce infectious yellows virus (LIYV)-encoded P26 is associated with plasmalemma deposits within LIYV-infected cells. Virology 333:367-73.
  16. Rubio, L., Tian, T., Yeh, H.H., Livieratos, Y., and Falk, B.W. (2002). De novo generation of Lettuce infectious yellows virus defective RNAs in protoplasts. Molecular Plant Pathology 3: 321-327.
  17. Yeh, H.H., Tian, T., Medina, V., and Falk, B.W. (2001). Green fluorescent protein expression from recombinant Lettuce infectious yellows virus defective RNAs originating from RNA 2. Virology 289:54-62.
  18. Yeh, H.H., Tian, T., Rubio, L., Crawford, B., and Falk, B.W. (2000). Asynchronous accumulation of Lettuce infectious yellows virus RNAs 1 and 2 and Identification of an RNA 1 trans Enhancer of RNA 2 Accumulation. Journal of Virology. 74:5762-5768.
  19. Rubio, L., Yeh, H.H., Tian, T., and Falk, B.W. (2000). A heterogeneous population of defective RNAs is associated with Lettuce infectious yellows virus (LIYV). Virology 271, 205-212.
  20. Tian, T., Rubio, L., Yeh, H-H., and Falk, B.W. (1999). Lettuce infectious yellows virus: in vitro acquission analysis using purified virions and the whitefly Bemisia tabaci.  Journal of General Virology. 80: 1111-1117.
  21. Falk, B.W., Tian, T., and Yeh, H.H. (1999) Luteovirus-associated viruses and sub-viral RNAs. Curr. Top. Microbiol. Immunol. 239:159-75.
  22. Yeh, H.H., Su, H.J., and Chao, Y.C. (1994). Genome characterization and identification of viral-associated dsDNA component of banana bunchy top virus. Virology 198, 645-652.
International Scholar Meeting Attended
  1. Chen, C.E., Wang, T.T., Chien, I.L. and Yeh, H. H. A seed storage protein, PAP85, involved in early stage of replication of Tobacco mosaic virus and ER morphology change. IS-MPMI 2012 XV International Congress. Kyoto, Japan. July 29- August 2, 2012.
  2. Kuan, T. and Yeh, H.H. Screening of metabolites derived from soil microorganisms for induction of plant resistance against Tobacco mosaic virus. IS-MPMI 2012 XV International Congress. Kyoto, Japan. July 29- August 2, 2012.
  3. Wang, H.I., Tang, C.Y., Lin, P.H., Fu, H.C., and Yeh, H.H. Elucidate the recombination relationships between genome components of Banana bunchy top virus. America Society for Virology Annual Meeting in Bozeman, Montana, USA. July 17-21, 2010.
  4. Fu, H.C., Wang, H.I., Lu, H.C., Chen, C.E., and Yeh, H.H. Defective DNA associated with mild strains of Banana bunchy top virus. America Society for Virology Annual Meeting in Bozeman, Montana, USA. July 17-21, 2010.
  5. Lu, H. C., Tsai, M.H., Wang, H-i., Su, H.J., and Yeh, H.H. Flexible interaction among viral-movement accessory components encoded by Cymbidium mosaic potexvirus facilitate host adaptation. America Society for Virology Annual Meeting in Ithaca, New York, USA. July 2008.
  6. Fu, H.C., Hu, J.M., Hung, T.H., Su, H.J., and Yeh, H.H. Recombination of integral and additional components in Banana bunchy top virus. America Society for Virology Annual Meeting in Ithaca, New York, USA. July 2008.
  7. Yeh, H.H. Strategies for functional validation of genes involved in reproductive stages of plants with long life cycle. International Symposium of Plant Regulatory RNAs. Taipei, Taiwan, March 22-23, 2007. (Invited speaker)
  8. Yeh, H.H. Development of Cymbidium Mosaic Virus Vectors for Functional Genomic Studies of Phalaenopsis spp. Plant Molecular Response to Stress and Plant Biotechnology. Taipei, Taiwan, May 2006. (Invited speaker).
  9. Lu, S.H., and Yeh, H.H. Development of Cymbidium mosaic virus expression vectors for functional genomic studies of Phalaenopsis spp. Fifth cross-strait symposium on plant molecular biology and biotechnology. Taichung, Taiwan, December, 2005. (Invited speaker)
  10. Lu, S.H., and Yeh, H.H. Development of Cymbidium mosaic virus expression vectors for Phalaenopsis spp. gene functional study. 18th World Orchid Conference in Dijon, France March 2005.
  11. Medina, V., Tian T., Yeh, H.H., Livieratos, I.C., and Falk, B.W.  Lettuce infectious yellow virus-encoded P26 protein accumulates in plasmalemma deposits.  America Society for Virology Annual Meeting in Colorado, USA.  July 2001.
  12. Yeh, H.H., Tian, T., Rubio, L., and Falk, B. W.  Delayed accumulation of Lettuce infectious yellow virus (LIYV) RNA2 and identification of a RNA 1-encoded enhancer of RNA 2 accumulation. America Society for Virology Annual Meeting in Colorado, USA. July 2000.
  13. Tian, T., Rubio, L., Yeh, H.H., Crawford, B., Medina, V. and Falk, B.W. Biology of criniviruses and whitefly-tranmission. XXI International Congress of Entomology.  Iguassu Falls, Brazil. August 2000.
  14. Falk, B.W., Tian T., Yeh, H.H., Rubio, L. and Medina, V.  Replication and whitefly transmission of the Crinivirus, Lettuce infectious yellows virus.  American Phytopathological Society (APS) Annual Meeting. New Orleans, USA.  August 2000.
  15. Rubio, L., Tian, T., Yeh, H.H. and Falk, B.W. Heterogeneous population of defective RNAs in plants infected with lettuce infectious yellows virus (LIYV). American Phytopathological Society and Canadian Phytopathological Society (APS/CPS) Annual meeting.  August 1999.
  16. Falk, B.W., Tian, T., Rubio, L., and Yeh, H.H. The emergence of whitefly-transmitted RNA viruses: the Criniviruses. American Phytopathological Society and Canadian Phytopathological Society (APS/CPS) Annual Meeting.  Montreal, Canada.  August 1999.
  17. Tian, T., Yeh, H.H., Rubio, L., and Falk, B.W. Replication of lettuce infectious yellows virus mutants in Nicotiana protoplasts.  America Society for Virology Annual Meeting in Vancouver, Canada. July 1998.

Manuscript Submitted or In Preparation
1. Wang, H.I., Chang, C.H., Lin, P.H., Fu, H.C., Tang, C.Y., and Yeh, H.H. (2013). Motif-based analysis reveals that recombination has been involved in the genome evolution of the multipartite viruses, Banana bunchy top virus. PLos One (submitted).
2. Chen, J.C., Lu, H.C., Chen, C.E., Hsu, H.F., Chen, H.H., and Yeh, H.H. (2013). The NPR1 Ortholog PhaNPR1 Is Required for the Induction of PhaPR1 in Phalaenopsis aphrodite. Plant Physiology and Biochemistry (Under review).

Book Chapters

  1. Lu, H.C., Wang, H.I., and Yeh, H.H. 2011. What we have learned from studies of the differential movement of mechanism of Cymbidium mosaic virus. In “Orchid biotechnology”. (Eds. W.H. Chen and H.W. Chen) pp329-340. World Scientifi Publishing Co. Pte. Ltd. Toh Tuck Link, Singapore.
  2. Lu, H.C., Chen, H.H., and Yeh, H.H. 2007. Application of virus-induced gene silencing technology in gene functional validation of orchids. In “Orchid biotechnology” (Eds. W.H. Chen and H.W. Chen) pp. 211-224. World Scientific Publishing Co. Pte, Ltd. Singapore.
  3. 曾顯雄、葉信宏、沈湯龍、張雅君、劉瑞芬。2009。微生物生物技術。於林長平、劉瑞芬、莊榮輝、丁詩同、李宜書等編著「生物技術概論」。P163~209。華杏出版機構。

Patents
1. Viral vectors for inducing gene inactivation and application thereof, Hsin-Hung Yeh, Hong-Hwa Chen and Shiang-Jia Lu.  US7,588,935B2 (2009)
2. 一種誘發植物產生基因不活化的病毒載體，葉信宏、陳虹華、陸祥家I344488 ， 中華民國專利

Technology Transfer
Rapid detection of orchid viruses by RT-PCR.

The detection method was transferred to an orchid nursery, Ox Orchid Farm, Taiwan. The company paid 300,000 NT plus 2% of total sales money per year for royalties under the guidelines set by the National Taiwan University and National Science Council.

 
Last Updated ( Tuesday, 7 May 2013 )  
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Department of Plant Pathology & Microbiology - National Taiwan University No.1, Sec.4, Roosevelt Road., Taipei, 10617 Taiwan
Phone: 886-2-3366-4603 Fax: 886-2-2363-6490
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