Yih-Loong Lai, Ph.D.

 PUBLICATIONS RESULTING FROM RESEARCH:  

1.          Garcia, A.C., Y.-L. Lai, B.A. Attebery, and E.B. Brown, Jr. In vivo buffer curves of arterial and mixed venous blood. Proc. Soc. Exp. Biol. Med. 137:237-242, 1971.

2.          Garcia, A.C., Y.-L. Lai, B.A. Attebery, and E.B. Brown, Jr. Lactate and pyruvate accumulation during hypocapnia. Respir. Physiol. 12:371-380, 1971.

3.          Lai, Y.-L., E.D. Martin, B.A. Attebery, and E.B. Brown, Jr. Mechanisms of extracellular pH adjustments in hypercapnia. Respir. Physiol. 19:107-114, 1973.

4.          Lai, Y.-L., B.A. Attebery, and E.B. Brown, Jr. Intracellular adjustments of skeletal muscle, heart and brain to prolonged hypercapnia. Respir. Physiol. 19:115-122, 1973.

5.          Lai, Y.-L., B.A. Attebery, and E.B. Brown, Jr. Mechanisms of cardiac muscle adjustment to hypercapnia. Respir. Physiol. 19:123-129, 1973.

6.          Gillespie, D.J., Y.-L. Lai, and R.E. Hyatt. Comparison of esophageal and pleural pressures in the anesthetized dog. J. Appl. Physiol. 35:709-713, 1973.

7.          Lai, Y.-L., J.R. Rodarte, and R.E. Hyatt. Esophageal elastance in awake and anesthetized recumbent dogs. J. Appl. Physiol. 41:272-275, 1976.

8.          Lai, Y.-L., J.R. Rodarte, and R.E. Hyatt. Effects of body position on lung emptying in recumbent anesthetized dogs. J. Appl. Physiol. 43:983-987, 1977.

9.          Lai, Y.-L., and J. Hildebrandt. Respiratory mechanics in the anesthetized rat. J. Appl. Physiol. 43:983-987, 1977.

10.      Lai, Y.-L., Y. Tsuya, and J. Hildebrandt. Ventilatory responses to acute CO₂ exposure in the rat. J. Appl. Physiol. 45:611-618, 1978.

11.      Lai, Y.-L., J.R. Rodarte, and R.E. Hyatt. Respiratory mechanics in recumbent dogs anesthetized with thiopental sodium. J. Appl. Physiol. 46:716-720, 1979.

12.      Lai, Y.-L. Lung volume and pleural pressure in the anesthetized hamster. J. Appl. Physiol. 46:927-931, 1979.

13.      Lai, Y.-L., W.J.E. Lamm, and J. Hildebrandt. Ventilation during prolonged hypercapnia in the rat. J. Appl. Physiol. 51:78-83, 1981.

14.      Lai, Y.-L., W.J.E. Lamm, and J. Hildebrandt. Mechanical properties of rat lung during prolonged hypercapnia. J. Appl. Physiol. 52:1156-1160, 1982.

15.      Lai, Y.-L., W.J.E. Lamm, and J. Hildebrandt. Suppression of endogenous hormones alters fetal lung mechanics and gas trapping. Lung 160:315-324, 1982.

16.      Lamm, W.J.E., J.R. Hildebrandt, J. Hildebrandt, and Y.-L. Lai. End-expiratory volume in the rat: effects of consciousness and body position. J. Appl. Physiol. 53:1071-1079, 1982.

17.      Lamm, W.J.E., Y.-L. Lai, and J. Hildebrandt. In vitro buffer value of brain tissue during prolonged hypercapnia. Respir. Physiol. 50:165-175, 1982.

18.      Lai, Y.-L., P.M. Smith, W.J.E. Lamm, and J. Hildebrandt. Sampling and analysis of cerebrospinal fluid for chronic studies in awake rats. J. Appl. Physiol. 54:1754-1757, 1983.

19.      Lai, Y.-L., W.J.E. Lamm, D.L. Luchtel, and J. Hildebrandt. Massive postmortem bronchoconstriction in guinea pig lungs. J. Appl. Physiol. 56:1032-1038, 1984.

20.      Lamm, W.J.E., Y.-L. Lai, and J. Hildebrandt. Histamine and leukotrienes mediate hypersensitivity to antigen in guinea pigs. J. Appl. Physiol. 56:1032-1038, 1984.

21.      Lai, Y.-L., W.J.E. Lamm, and J. Hildebrandt. Factors affecting massive postmortem bronchoconstriction in guinea pig lungs. J. Appl. Physiol. 57:692-697, 1984.

22.      Hopping, F.G., Jr., J.C. Stothert, I.A. Greaves, Y.-L. Lai, and J. Hildebrandt. Lung recoil: elastic and rheological properties. In: Handbook of Physiology, Section 3. Respiratory System, vol. III. Mechanics of Breathing. Ed. P.T. Macklem and J. Mead. Bethesda, MD: American Physiological society, 1986. p. 659-692.

23.      Lai, Y.-L., and L. Diamond. Comparison of five methods of analyzing respiratory pressure-volume curves. Respir. Physiol. 66:147-155, 1986.

24.      Diamond, L., and Y.-L. Lai. Augmentation of elastase-induced emphysema by cigarette smoke: effects of reducing tar and nicotine content. J. Toxicol. Environ. Health 20:287-301, 1987.

25.      Lai, Y.-L., and L. Diamond. Effects of high or low tar cigarette smoke exposure on elastase induced emphysema. In: Pulmonary Emphysema and Proteolysis. ed. J.C. Taylor and C. Mittmann. New York: Academic Press, 1987. P. 523-533.

26.      Lai, Y.-L., and A.F. Cornett. Substance P-inducing massive postmortem bronchoconstriction in guinea pig lungs. J. Appl. Physiol. 62:746-751, 1987.

27.      Lai, Y.-L. Calcium dependency of massive postmortem bronchoconstriction in guinea pig lungs. Respir. Physiol. 68:41-51, 1987.

28.      Lai, Y.-L. Fluid trapping in postmortem guinea pig lungs. Lung 165:213-223, 1987.

29.      Ko, W.C., and Y.-L. Lai. Cyclic GMP affecting the tracheal nonadrenergic noncholinergic inhibitory system. Respir. Physiol. 73:351-362, 1988.

30.      Ko, W.C., and Y.-L. Lai. The tracheal nonadrenergic noncholinergic inhibitory system during antigen challenge. Respir. Physiol. 74:129-138, 1988.

31.      Lai, Y.-L. Maximal expiratory flow in the guinea pig. Lung 166:303-313, 1988.

32.      Lai, Y.-L., S. Ganesan, and S.J. Lai-Fook. Airway resistance measured in liquid-trapped guinea pig lungs by micropuncture. J. Appl. Physiol. 65:2446-2452, 1988.

33.      Diamond, L., E.C. Kimmel, Y.-L. Lai, and D.W. Winsett. Augmentation of elastase-induced emphysema by cigarette smoke: effects of reduced nicotine content. Am. Rev. Respir. Dis. 138:1201-1206, 1988.

34.      Gairola, C.G., N.I. Galicki, C. Cardozo, Y.-L. Lai, and M. Lesser. Cigarette smoke stimulates cathepsin B activity. J. Lab. Clin. Med. 114:419-425, 1989.

35.      Lai, Y.-L. Oxygen radicals in capsaicin-induced bronchoconstriction. J. Appl. Physiol. 68:568-573, 1990.

36.      Lai, Y.-L., and L. Diamond. Inhibition of porcine pancreatic elastase-induced pulmonary emphysema by eglin-c. Exp. Lung Res. 16:547-557, 1990.

37.      Shi, M.X.J., and Y.-L. Lai. The role of tachykinins in air ventilation-induced bronchoconstriction. Respir. Physiol. 81:75-86, 1990.

38.      Lai, Y.-L., J.W. Olson, and M.N. Gillespie. Ventilatory dysfunction precedes pulmonary hypertension in monocrotaline-treated rats. J. Appl. Physiol. 70:561-566, 1991.

39.      Lai, Y.-L. Role of the axon reflex in capsaicin-induced bronchoconstriction. Respir. Physiol. 83:35-46, 1991.

40.      Lai, Y.-L. Endogenous tachykinins in antigen-induced acute bronchial responses of guinea pigs. Exp. Lung Res. 17:1047-1060, 1991.

41.      Shih, W.-J., Y.-L. Lai, C. Coulston, F. Grunwald, J.J. Coupal, L.-Y. Lee, U.Y. Ryo, and H.J. Biersack. Diffuse pulmonary ^99mTc HM-PAO uptake associated with cirarette smoke exposure: a rat study. NucCompact 22:99-100, 1991.

42.      Lai, Y.-L., P.G. Reiinhart, A.A. Thacker, and K.-R. Zhou. Role of leukocyte depletion in noncholinergic bronchoconstriction of guinea pigs. Respir. Physiol. 86:139-146, 1991.

43.      Zhang, H.-Q., and Y.-L. Lai. Nicardipine suppresses mediator-induced constriction of airway smooth muscle in guinea pigs. Lung 169:343-355, 1991.

44.      Lai, Y.-L., and L. Diamond. Cigarette smoke exposure dose not prevent cadium-induced lung fibrosis in rats. J. Toxicol. Environ. Health 35:63-76, 1992.

45.      Zhou, K.-R., and Y.-L. Lai. α-Difluoromethylornithine attenuates monocrotaline-induced airway/lung dysfunction. J. Appl. Physiol. 72:1914-1921, 1992.

46.      Lai, Y.-L. Comparative ventilation of the normal lung. In: A Comprehensive Treatise On Pulmonary Toxicology, Vol. I, Sec. II. Comparative Respiratory Physiology of the Normal Lung. Ed. R.A. Parent. CRC Press, boca Raton, FL, Chapter 17, 1992. P. 217-239.

47.      Fang, Z.X., and Y.-L. Lai. Oxygen radicls in bronchoconstriction of guinea pigs elicited by isocapnic hyperpnea. J. Appl. Physiol. 74:627-633, 1993.

48.      Shih, W.-J., Y.-L. Lai, J.J. Coupal, and G. Simmons. I-123 HIPDM pulmonary imaging demonstrates elastase-induced pulmonary emphysema. Lung 171:31-41, 1993.

49.      Shih, W.-J., S.R. Rehm, F. Grunwald, J.J. Coupal, H.J. Biersack, R. Berger, S. Bradenburg, Y.-L. Lai, U.Y. Ryo, and M.L. Dillon. Lung uptake of Tc-99m HM-PAO in cigarette smokers expressed by lung/liver activity ratio. Clin. Nucl. Med. 18:227-230, 1993.

50.      Lai, Y,-L., R.C. Mehta, A.A. Thacker, S.-D. Yoo, P.J. McNamara, and P.P. DeLuca. Saustained bronchodilation with isoproterenol poly(glycolide-co-lactide) microspheres. Pharmaceut. Res. 10:119-125, 1993.

51.      Zhang, H.-Q., and Y.-L. Lai. Axon relflex in resiniferaroxin-induced bronchoconstriction of ginea pigs. Respir. Physiol. 92:13-25, 1993.

52.      Zhou, K.-R., and Y.-L. Lai. Capsaicin pretreatment attenuates monocrotaline-induced ventilatory dysfunction and pulmonary hypertension. J. Appl. Physiol. 75:2781-2788, 1993.

53.      Zhang, H.-Q., and Y.-L. Lai. Role of vagus nerves in noncholinergic airway constriction. Respir. Physiol. 94:285-295, 1993.

54.      Lai, Y.-L., Z.X. Fang, and H-Q. Zhang. Noncholinergic airway constriction. Role of axon reflex and oxygen radicals. Chinese J. Physiol. 36:133-140, 1993.

55.      Zhang, H.-Q., and Y.-L. Lai. Intratracheal antioxidants attenuate exsanguinations-induced bronchoconstriction in guinea pigs. J. Appl. Physiol. 76:553-559, 1994.

56.      Zhou, K.-R., and Y.-L. Lai. Oxygen radicals in exsanguinations-induced bronchoconstriction of guinea pigs. Lung 172:281-291, 1994.

57.      Lai, Y.-L., A.A. Thacker, and C.G. Gairola. Sidestream cigarette smoke exposure and bronchial hyperreactivity during early life. J. Appl. Physiol. 77:1868-11874, 1994.

58.      Kang, B.C., T. Kambara, D.K. Yun, J. Hoppe, and Y.-L. Lai. Development of cockroach allergic guinea pig by simple room air contamination. Int. Arch. Allergy Immunol. 107: 569-575, 1995.

59.    Shih, W.-J., J. Coupal, Y.-L. Lai, F. Grunwald, and H. Biersack. Diminished Tc-99m HMPAO uptake in exsmokers' lungs. Clin. Nuclear Med. 20:788-791, 1995.

60.    Zhang, H.-Q., H.-H. Tai, and Y.-L. Lai. Age-dependent mechanism in guinea pig bronchoconstriction induced by exsanguination. Respir.Physiol. 99: 361-369, 1995.

61.    Lai, Y.-L., C.-F. Chen, C.T. Chien, H.-L. Shiao, A.A. Thacker, and H.-Q. Zhang. Capsaicin pretreatment attenuates chronic hypoxic pulmonary hypertension. Respir.Physiol. 99: 283-289, 1995.

62.   Kang, B.C., K. Zhou, Y.-L. Lai, and C.B. Hong. Experimental asthma developed by room air contamination with cockroach allergen. Int. Arch. Allergy Immunol. 111: 299-306, 1996.

63.    Kuo, P.-H., H.-D. Wu, C.-J. Yu, S.-C. Yang, Y.-L. Lai, and P.-C. Yang. Efficacy of tracheal gas insufflation in acute respiratory distress syndrome with permissive hypercapnia. Am. J. Respir. Crit. Care Med. 154: 612-616, 1996.

64.    Zhang, H.-Q., and Y.-L. Lai. Oxygen radicals in nonvagal component of noncholinergic airway constriction. Respir. Physiol. 104: 213-220, 1996.

65.    Reinhart, P.G., Y.-L. Lai, and C.G. Gairola. Amiodarone-induced pulmonary fibrosis in Fisher 344 rats. Toxicology 110: 95-101, 1996.

66.    Hsu C.-H., K.-Y. Chua, M.-H. Tao, Y.-L. Lai, H.-D. Wu, S.-K. Huang, and K.-H. Hsieh. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nature Med. 2: 540-544, 1996.

67.    Chien, C.T., T.C. Fu, Y.-L. Lai, Y.C. Chang, and C.F. Chen. Renal neural response to ischemic renal failure in chronic hypoxic rats. J. Autonom. Nerv. Syst. 58: 11- 17, 1996.

68.    Lai, Y.-L., A.A. Thacker, and J.N. Diana. Hypoxemia and elevated tachykinins in rat monocrotaline pneumotoxicity. Lung 174: 195-203, 1996.

69.    Lai, Y.-L., and L.Y. Chiang. Water-soluble fullerene derivatives attenuate exsanguination-induced bronchoconstriction of guinea pigs. J. Autonom. Pharmacol. 17: 229-235, 1997.

70.    Lai, Y.-L., J. Wang, and S.J. Lai-Fook. Lung tissue resistance measured by saline-filled guinea pig lungs by micropuncture. Lung 175: 395-403, 1997.

71.    Lai, Y.-L., W.-Y. Chiou, and L.Y. Chiang. Fullerene derivatives attenuate  bronchoconstriction induced by xanthine-xanthine oxidase. Fullerene Sci. Technol. 5: 1057-1065, 1997.

72.    Lai, Y.-L., W.J.E. Lamm, and J. Hildebrandt. Comparison of five measures derived from in vivo pulmonary vascular pressure-flow curves. Chinese J. Physiol. 40: 45-49, 1997.

73.    Hartsfield, C.L., D. Lipke, Y.-L. Lai, D.A. Cohen, and M.N. Gillespie. Pulmonary mechanical and immunologic dysfunction in a murine model of AIDS. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L699-L706, 1997.

74.    Lai, Y.-L., and K.-R. Zhou. Eglin-c prevents monocrotaline-induced ventilatory dysfunction. J. Appl. Physiol. 82: 324-328, 1997.

75.    Hsu, T.H., Y.-L. Lai, and Y.R. Kou. Acetylcholine and tachyknin receptor antagonists attenuate wood smoke-induced bronchoconstriction in guinea pigs. Eur. J. Pharmacol. 360: 175-183,1998.

76.    Hsu, T.H., Y.-L. Lai, and Y.R. Kou. Smoke-induced airway hyperresponsiveness to inhaled wood smoke in guinea pigs:tachykininergic and cholinergic mechanisms. Life Sci. 63: 1513-124,1998.

77.    Lamm, W.I.E., Y.-L. Lai, and J. Hildebrandt. The role of the inhibitory nonadrenergic noncholinergic system in antigen-induced pulmonary hypersensitivity. Chinese J. Physiol. 41: 139-144, 1998.

78.    Lai, Y.-L., and Y.-J. Lin. Elastase in hyperpnea-induced guinea pig airway constriction. Eur. J. Pharmacol. 359: 171-176, 1998.

79.    Lai, Y.-L.. H.-D. Wu, and C.-F. Chen. Atioxidants attenuate chronic hypoxic pulmonary hypertension. J. Cardiovasc. Pharmacol. 32: 714-720,1998.

80.   Lin. C.W., and Y.-L. Lai. Tachykinins in propranolol-augmented, hyperpnea-induced bronchoconstriction in Taida guinea pigs: effects of dimethylthiourea. J. Autonom. Pharmacol. 18: 139-147, 1998.

81.    Lai, Y.-L., C.W. Lin, and L.-C. Lai. Attenuation of isocapnic hyperpnea-elicited guinea pig bronchoconstriction by chronic hypoxia. Eur. Respir. J. 11: 1075-1080, 1998.

82.   Lin, K.-H., Y.-L. Lai, H.-D. Wu, T.-Q. Wang, and Y.-H. Wang. Effects of abdominal binder and electrical stimulation on cough in spinal cord injured patients. J. Formosan Med. Assoc. 97: 292-295, 1998.

83.    Chen, L.-W., C.-F. Chen. and Y.-L. Lai. Chronic activation of neurokinin-1 receptor induces pulmonary hypertension in rats. Am. J. Physiol. 276:H1543-H1551, 1999.

84.    Lai, Y.-L., W.-Y. Chiou, F.J. Lu, and L.Y. Chiang. Roles of oxygen radicals and elastase in citric acid-induced airway constriction of guinea pigs. Br. J. Pharmacol. 126: 778-784, 1999.

85.   Lai, Y.-L., and S.-P. Lee. Mediators in hyperpnea-induced bronchoconstriction of guinea pigs. Naunyn-Schmiedeberg’s Arch. Pharmacol. 360:597-602, 1999.

86.   Lin, K.-H., Y.-L. Lai, H.-D. Wu, T.-Q. Wang, and Y.-H. Wang. Cough threshold in people with spinal cord injuries. Physical Therapy 79:1026-1031, 1999.

87.   Lai, Y.-L., and H.-C. Chou. Respiratory mechanics and maximal expiratory flow in the anesthetized mouse. J. Appl. Physiol. 88:939-943, 2000.

88.   Hsu, T.H., Y.-L. Lai, and Y.R. Kou. Wood smoke-induced airway hyperreactivity in guinea pigs: time course, and role of leukotrienes and hydroxyl radical. Life Sci. 66:971-980, 2000.

89.        Lai, Y.-L., and C.F. Lee. Mediators and oxygen radicals in hyperpnea-induced airway constriction of guinea pigs. Lung 178: 213-223, 2000.

90.        Katzman, N.J., and Y.-L. Lai. Capsaicin pre- and post-treatment on rat monocrotaline pneumotoxicity. Chinese J. Physiol. 43: 171-178, 2000.

91.        Chen, M.-J., L.Y. Chiang, and Y.-L. Lai. Reactive oxygen species and substance P in monocrotaline-induced pulmonary hypertension. Toxicol. Appl. Pharmacol. 171: 165-173, 2001.

92.        Yu, C.-C., and Y.-L. Lai. The in vivo pressure-flow curve in unilateral rat lung ischemia-reperfusion injury. J. Appl. Physiol. 90: 1865-1870, 2001.

93.        Lai, Y.L. Tachykinins in airway constriction. Thorac. Med. 16: 148-155, 2001.

94.        Lai, Y.-L., S.-C. Lee, L.-C. Lai, F.-C. Hu, T.-L. Tsai, and Y.-F. Tsai. Catecholamines in hyperpnoea-induced airway constriction of guinea pigs. J. Auton. Pharmacol. 21: 151-157, 2001.

95.        Lee, Y.-L., Y.-L. Ye, C.-I. Yu, Y.-L. Wu, Y.-L. Lai, P.-H. Ku, R.-L. Hong, and B.-L. Chiang. Construction of single-chain interleukin-12 DNA plasmid to treat airway hyperresponsiveness in an animal model of asthma. Hum. Gene Ther. 12: 2065-2079, 2001.

96.        Lai, Y.-L., W.-Y. Chiou, and F.-J. Lu. Hyperpnea-induced production of TBHP-initiated chemiluminescence in guinea pigs. Life Sci. 70: 1271-1277, 2002.

97.        Lee, S.-C., and Y.-L. Lai. Endothelin-1 in citric acid aerosol inhalation-induced airway constriction of guinea pigs. Chinese J. Physiol. 45: 25-31, 2002.

98.        Lai, Y.-L., S.J. Chu, M.-C. Ma, and C.-F. Chen. Temporal increase in the reactivity of pulmonary vasculature to substance P in chronically hypoxic rats. Am. J. Physiol. 282: R858-R864, 2002.

99.        Lai, Y.-L., and P.-c. Huang. Reactive oxygen species in sustained airway constriction induced by citric acid aerosol inhalation. Eur. J. Pharmacol. 452: 229-233, 2002.

100.    Lai, Y.-L., P. Murugan, and K.C. Hwang. Fullerene derivative attenuates ischemia-reperfusion-induced lung injury. Life Sci. 72: 1271-1278, 2003.

101.    Chen, M-J, and Y.-L. Lai. Tachykinin dysfunction attenuates monocrotaline-induced pulmonary hypertension. Toxicol. Appl. Pharmacol. 187: 178-185, 2003.

102.    Lai, Y.-L., and F.-C. Tang-Tei. Airway hyperresponsiveness in sensitized, antigen-challenged guinea pigs. Chinese J. Physiol. 46: 9-13, 2003.

103.    Yu, C.-C., and Y.-L. Lai. Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. Life Sci. 2171-2184, 2003.

104.    Huang, H.-Y., and Y.-L. Lai. Lipopolysaccharide induces preprotachykinin gene expression. Am. J. Respir. Cell Mol. Biol. 29: 606-612, 2003.

105.    Lai, Y.-L., S.C. Yu, and M.-J. Chen. RNA interference prevents lipopolysaccharide-induced preprotachykinin gene expression. Toxicol. Appl. Pharmacol. 193: 47-54, 2003.

106.    Liu, Y.H., M.C. Kao, Y.-L. Lai, and J.J. Tsai. Efficacy of local nasal immunotherapy of Dp2-induced airway inflammation in mice: Using Dp2 peptide and fungal immunomodulatory peptide. J. Allergy Clin. Immunol. 112: 301-310, 2003.

107.    Liu, Y.-H., C.-F. Tsai, M.-C. Kao, Y.-L. Lai, and J.-J. Tsai. Effectiveness of Dp2 nasal therapy for Dp2-induced airway inflammation in mice: using oral Ganoderma lucidum as an immunomodulator. J. Microbiol. Immunol. Infect. 36: 236-242, 2003.

108.    Tsao, P.N., Y.N. Su, H. Li, P.H. Huang, C.T. Chien, Y.-L. Lai, C.N. Lee, C.A. Chen, W.F. Cheng, S.C. Wei, C.J. Yu, F.J. Hsieh, and S.M. Hsu. Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema. Am. J. Respir. Crit. Care Med. 169: 505-511, 2003.

109.    Lai, Y.-L., and T.C. Law. Chronic hypoxia- and monocrotaline-induced elevation in HIF-1α level and pulmonary hypertension. J. Biomed. Sci. 11: 315-321, 2004.

110.    Chen,Y.-W., K.C. Hwang, C.-C. Yen, and Y.-L. Lai. Fullerene derivatives protects against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs. Am. J. Physiol. 287: R21-R26, 2004.

111.    Wu, L.-L., F.-J. Lu, and Y.-L. Lai. Mast cells and reactive oxygen species in citric acid-induced airway constriction. J. Appl. Physiol. 96: 1879-1885, 2004.

112.    Lai, Y.-L., K.-C. Lee, and P.-H. Kuo. Detection of mediator-induced airway   constriction by barometric plethysmography in mice. Chinese J. Physiol. 47: 161-167, 2004.

113.    Hussain, A.A., A. Dakkuri, Y.-L. Lai, A. Traboulsi, and M.A. Hussain. Nasal administration of albuterol: an alternative route of delivery. J. Pharm. Pharmacol. 56: 1211-1215, 2004.

114.    Lai, Y.-L., and T.-Y. Lin. Mast cells in citric acid-induced cough of guinea pigs. Toxicol. Appl. Pharmacol. 202: 18-24, 2005.

115.    Lin, C.-H., and Y.-L. Lai. Mast cell mediators in citric acid-induced airway constriction of guinea pigs. Toxicol. Appl. Pharmacol. 206: 343-350, 2005.

116.    Lai-Fook, S.J., and Y.-L. Lai. Airway resistance due to aveolar gas compression measured by barometric plethysmography in mice. J. Appl. Physiol. 98: 2204-2218, 2005.