96學年度上學期 生物資訊學導論 課程首頁

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課程大剛	課程內容	指定作業	公布事項

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課程名稱: 生物資訊學導論 (Introduction of Bioinformatics)

課程編號: 621 U6390

課程首頁: http://homepage.ntu.edu.tw/~lyliu/IntroBioinfo/

先修科目: 生物統計學

上課時間: 每週五 1:20-4:20 農藝館 108

授課教師: 劉力瑜

TEL: 02-33664792
E-mail: lyliu@ntu.edu.tw
Office: 五號館(農工系館)二樓 202 室
Office Hours: Tue-Thr 12:30-1:30PM; Fri 12:00-1:00PM

教材課本:

1. Bioinformatics and Computational Biology Solutions Using R and Bioconductor (2005).
    Edited by R. Gentleman, V. J. Carey, W. Huber, R. A. Irizarry, and S. Dudoit
2. Statistical Methods in Bioinformatics, 2nd Ed. (2005).
    Edited by Warren J. Ewens and Gregory R. Grant

課程內容:

I. Basics of R/Bioconductor

II. Microarray Data Analysis:
1. Introduction of Microarry
2. Distance Measures in DNA Microarray Data Analysis
3. Cluster Analysis of Genomic Data
4. Analysis of Differential Gene Expression Studies
5. Multiple Testing Procedures and Applications to Genomics
6. Machine Learing Concepts and Tools for Statistical Genomics
7. Data Visualization
8. Preprocessing High-density Oligonucleotide and Two-Color Spotted Arrays
9. Preprocessing SELDI-TOF Mass Spectrometry Protein Data


III. Sequence Analysis:
1. The Analysis of One DNA Sequence
2. Alignment Algorithms for Multiple DNA or Protein Sequences
3. BLAST


IV. Phylogeny Inference (if possible)


• 評分標準: Homework 30%, Oral Presentation 30%, Final Project 40%.
  
  
• 其它注意事項:
  1. 考試若有作弊情事一律依校規處份 (附件: 國立臺灣大學學生個人獎懲辦法)。
  2. 請隨時查閱課程網站以獲知最新公告訊息。
• 附件:
  1. 國立臺灣大學學生個人獎懲辦法
  2. 國立臺灣大學學生請假辦法