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《預測微生物學研究室》 主持人 盧冠宏 (Kuan-Hung Lu, Ph.D.) 藥學博士 藥師（2001）、食品技師（2018）專技高考及格 地址：100 臺北市中正區徐州路 17 號
7 樓 714 室 E-mail: khlu@ntu.edu.tw Tel.: (02)3366-8093 Google Scholar: (H-index = 19) https://scholar.google.com/citations?hl=zh-TW&user=yGmY7hcAAAAJ |
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一、現職：
國立臺灣大學環境與職業健康科學研究所 專案助理教授 (2021/8 ~ 迄今)
國立臺灣大學食品安全與健康研究所 合授教師 (2021/8 ~ 迄今)
二、學歷：
中國醫藥大學中國藥學暨中藥資源學系 藥學博士 (2005~2011)
中國醫藥大學中國藥學研究所 藥學碩士 (2001~2003)
中國醫藥學院藥學系 藥學士 (1997~2001)
三、經歷：
國立臺灣大學食品安全與健康研究所 專案助理教授 (2020/3
~ 2021/7)
國立臺灣大學食品科技研究所 博士後研究員 (2012/12 ~ 2020/2)
國立臺灣大學醫學系 博士後研究員 (2011/10~2012/11)
衛生署管制藥品管理局製藥工廠 國防訓儲研發人員 (2003/10 ~ 2007/10)
四、專業領域：
1. 預測微生物學 (Predictive Microbiology)
2. 食品安全性評估 (Safety Evaluation)
3. 癌症化學預防 (Cancer Chemoprevention)
4. 機能性食品功效驗證 (Functional Foods)
五、研究方向：
1. 微生物風險評估：
利用預測微生物學建立病原菌於食品基質之生長與殺菌模型，應用於預測環境因子 (如：溫度、水活性、鹽度) 對於生長動力學參數 (如：μmax, λ, Ymax) 與熱失活動力學參數 (如：D-value,
z-value) 之影響，可供後續套用各種情境 (scenario) 下之微生物暴露評估。目前已建立金黃色葡萄球菌於肉鬆飯糰與生菜沙拉之一級與二級生長預測模式，以及泌尿道致病性大腸桿菌於牛肉之生長模型和舒肥雞胸肉之殺菌模型，並完成驗證試驗，接著可基於臺灣的冷鏈運輸與消費者的飲食習慣，進行即時餐食從工廠端至消費者端之微生物風險評估。相關成果發表於IAFP annual meeting 2018; IAFP annual meeting
2019; Food Microbiol. 2020, 89, 103374; TSRA annual meeting 2022; Food Res. Int. 2023, 164, 112316; ICPMF12 2023, Foodborne Pathog.
Dis. 2023 (Accepted)。
2. 食品毒理與安全性評估：
因應機能性食品產品產業鏈之研發需求，針對可供食品食用原料 (如: 天麻、菇類、大蒜精油)，進行基因毒性試驗 (如：沙門氏菌回復突變試驗、體外哺乳類細胞之染色體異常分析、囓齒類周邊血液之微核測試法) 以及 28 天餵食毒性試驗，藉以測定無毒性顯示之劑量 (NOAEL)，以利未來開發成為健康食品，相關成果發表於AsiaTOX 2018; CGCM 2018; Regul.
Toxicol. Pharmacol.
2020, 114, 104657; J. Tradit. Complement. Med. 2022, 12, 536-544。
3. 植化素之癌症化學預防：
以細胞模式與動物模式探討天然產物 (natural products) 對於癌症生成的預防與抑制效果，並探究其誘導癌細胞株之細胞凋亡 (apoptosis)、細胞週期停滯
(cell cycle arrest)、細胞自噬 (autophagy) 及細胞訊息傳遞
(cell signaling) 之影響。肝癌方面：苦橙萃取物 (J. Funct.
Food. 2019, 60, 103404)、大蒜 (J. Tradit. Complement. Med. 2013, 3, 159-162)；血癌方面：血藤萃取物 (Evid.-based
Complement Altern. Med. 2012, 921430; Integr. Cancer Ther.
2010, 9, 298-308)。
4. 護肝與抗憂鬱機能性食品研發：
透過產學合作計畫的方式，運用動物模式協助廠商開發機能性食品原料或驗證產品功效，以利廠商技術轉移或取得健康食品認證。護肝功效：山苦瓜萃取物 (Food Funct.
2014, 5, 1027-1037)、人參精華液 (J. Ginseng.
Res. 2017, 41, 316-325)、典藏牛樟芝 (J. Tradit. Complement.
Med. 2020, 10, 166-174)；抗憂鬱功效：大蒜精油 (Food Funct. 2019, 10,
8094-8105; Phytother. Res. 2021, 35, 5133-5142)、天麻水萃物 (Curr. Pharmacol. Rep.
2018, 4, 220-237)、茯苓萃取物 (J. Ethnopharmacol. 2020, 258, 112566)、蜜環菌萃取物 (J. Ethnopharmacol.
2021, 265, 113395.)、北蟲草萃取物 (J. Ethnopharmacol.
2021, 276, 114194)。
六、獲補助之研究計畫
[科技部]
運用預測微生物學建立泌尿道致病性大腸桿菌於即食肉品之生長與殺菌模型（計畫主持人，2020/9~2022/7）
七、研究室成員
【臺大食安所碩士班】
[108級] 俞沛恩、許珈榕
[109級] 高子評、李昀蓉、張雅筑
[110級] 糠君宜、吳柳豔
八、任教科目
[國立臺灣大學]
食品化學 (獨授)
食品與用藥安全 (獨授)
微生物生物技術與風險評估 (合授)
高等環境衛生學 (合授)
環境職業健康科學專題討論 (合授)
環境職業衛生特論 (合授)
九、指導學生獲獎紀錄：
1. 2022年臺大公共衛生學院研究生優秀論文獎【碩士班 - 優等獎】：李昀蓉
Yun-Jung Lee,
Yi-Chun Pan, Ching-Wen Chang, Kuan-Hung Lu* (2023). Thermal
inactivation kinetics of uropathogenic Escherichia coli in sous-vide processed chicken breast. Food Research International 164, 112316. (SCI, IF: 7.425, Ranking:
13/144)
2. 臺灣風險分析學會2022年會暨研討會海報論文發表競賽【第一名】：李昀蓉
Yun-Jung Lee, Kuan-Hung Lu*. Emerging foodborne urinary tract infection:
The prevalence and survival modeling of uropathogenic
Escherichia coli in chicken meat in
Taiwan.
3. 臺灣風險分析學會2022年會暨研討會海報論文發表競賽【第二名】：高子評
Tzu-Ping Kao, Kuan-Hung Lu*. Emerging foodborne
pathogens: The prevalence and growth modeling of uropathogenic
Escherichia coli in raw beef in
Taiwan.
4. 111學年度環職食安學群海報論文展【碩士班 - 金獎】：吳柳豔
Liu-Yean Goh, Kuan-Hung Lu*. Modeling the growth
of uropathogenic Escherichia
coli in sugarcane juice as a function of storage temperature.
5. 110學年度環職食安學群海報論文展【碩士班 – 銅獎】：李昀蓉
Yun-Jung Lee, Kuan-Hung Lu*. Emerging foodborne urinary tract infection:
Modeling the thermal inactivation of uropathogenic Escherichia coli in sous-vide processing chicken breast.
6. 110學年度環職食安學群海報論文展【碩士班 – 佳作獎】：高子評
Tzu-Ping Kao, Kuan-Hung Lu*. Growth kinetics of uropathogenic Escherichia
coli in raw and cooked beef.
7. 110學年度環職食安學群海報論文展【碩士班 – 最佳人氣獎】：張雅筑
Ya-Zhu Zhang, Kuan-Hung
Lu*, Ching-Wen Chang*. Optimal
biofilm formation of Listeria
monocytogenes on polypropylene surface.
十、其他教學經驗
1. 國立空中大學：食品安全與衛生 (2018暑期線上課程, 負責單元：食品安全及風險分析概論、食品毒理與安全性評估、認識食品與藥物交互作用)
2. 耕莘健康管理專科學校：食品衛生與保健 (2015/9 ~ 2016/1)、健康與生活 (2015/9 ~ 2016/1)
3. 新北市藥師公會：食品安全暨用藥安全宣導講師 (2015/7 ~ 2015/12)
4. 杜邦台灣分公司：食品衛生安全及法規訓練研習班 (2015/2 ~ 2015/5)
5. 佛光大學：同類療法 (2014/9 ~ 2015/1)
十一、邀請演講
1. 國立臺灣大學 環境與職業健康科學研究所, 專題演講：
「《預測微生物學》於食品安全與風險評估之應用」 (2020/4)
2. 國立臺灣大學 食品安全與健康研究所, 專題演講：
「《預測微生物學》於食品安全與風險評估之應用」 (2020/4)
3. 台灣食品保護協會, 台大食安講座：
「食在藥小心：認識食品與藥物交互作用」 (2016/7、2017/8、2018/7)、「食安防身術：認識食品毒理與風險分析」 (2018/11)
4.
國立臺灣科技大學 化學工程系,
專題演講：
「臺灣食品安全事件的省思：從危機處理提升至風險管理」 (2016/4)、「食安防身術：認識食品毒理與風險分析」 (2019/10)
5. 中華紅心字會, 社區關懷講座：
「長期照顧與用藥安全實務課程」 (2017/1)、「照顧身心--從銀髮族用藥問題談居家用藥安全」 (2017/9)
6. 2016 宜蘭綠色博覽會：
「食在藥小心：淺談食品與藥物交互作用」(2016/5)
7. CGCM Meeting 2016 (15th Meeting of
Consortium for Globalization of Chinese Medicine)
Invited Speaker: Immediate changes of meridian energy and personal feelings
after ginger tea and coconut water consumption by young subjects with hot constitution
(2016/8)
十二、學術服務
[Invited Referee]
Behavioural Brain Research (ISSN: 0166-4328)
Biomedicine &
Pharmacotherapy (ISSN: 0753-3322)
Ecotoxicology and Environmental Safety (ISSN: 0147-6513)
Food Control (ISSN: 0956-7135)
Food and Chemical Toxicology (ISSN: 0728-6915)
International Journal of Biological
Macromolecules (ISSN: 0141-8130)
Journal of Chromatography B (ISSN:
1570-0232)
Journal of Ethnopharmacology
(ISSN: 0378-8741)
Journal of Traditional and Complementary Medicine (ISSN: 2225-4110)
Pharmaceutical Biology (ISSN: 1388-0209)
Phytotherapy Research (ISSN: 0951-418X)
十三、榮譽
1. 中國醫藥大學：藥學院博士生獎學金 (2011)
2. 實踐大學：第九屆食品技師專業學分班成績優良獎 (2017)
3. Food and Chemical Toxicology: Outstanding Contribution in Reviewing (2017)
十四、證照與專業資格
1. 國家專技高考藥師 (考試院, 2001)
2. 國家專技高考食品技師 (考試院, 2018)
3. 保健食品初級工程師 (經濟部工業局, 2014)
4. Preventive Controls Qualified Individual
(PCQI):
by the Food Safety Preventive Controls Alliance (FSPCA), USA (2018)
5. Certificate of Risk Assessment Training
Program:
by the Joint Institute for Food Safety and Applied Nutrition (JIFSAN), USA
(2012)
十五、學術著作
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(A) 期刊論文 |
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1.
Kuan-Hung
Lu*, Lih-An Hsu, Yi-Chun Pan, Yun-Ju Huang, Liu-Yean Goh, Chun-Yi
Kang, Lee-Yan Sheen (2023). Modeling the temperature effect on the growth of uropathogenic Escherichia
coli in sous-vide chicken
breast. Foodborne Pathogens and Disease
(Accepted). (SCI, IF: 3.788, Ranking: 56/144) *corresponding author 2.
Yun-Jung Lee, Yi-Chun Pan,
Ching-Wen Chang, Kuan-Hung Lu*
(2023). Thermal inactivation kinetics of uropathogenic
Escherichia coli in sous-vide processed chicken breast. Food Research International 164,
112316. (SCI, IF: 7.425, Ranking: 13/144) *corresponding author 3.
Huai-Syuan Huang, Yu-En
Lin, Suraphan Panyod,
Rou-An Chen, Ying-Cheng Lin, Laura Min Xuan Chai,
Cheng-Chih Hsu, Wei-Kai Wu, Kuan-Hung
Lu, Yun-Ju Huang, Lee-Yan Sheen (2022). Anti-depressive-like and
cognitive impairment alleviation effects of Gastrodia elata Blume water extract is related
to gut microbiome remodeling in ApoE−/− mice
exposed to unpredictable chronic mild stress. Journal of Ethnopharmacology 302, 115872. (SCI, IF: 5.195,
Ranking: 4/30) 4.
Yu-En
Lin, Meng-Hsuan Lin, Ti-Yen
Yeh, Yi-Syuan Lai, Kuan-Hung
Lu, Huai-Syuan Huang, Fu-Chuo Peng, Shing-Hwa Liu, Lee-Yan Sheen (2022). Genotoxicity and 28-day
repeated dose oral toxicity study of garlic essential oil in mice. Journal of Traditional and Complementary Medicine 12, 536-544. (SCI, IF: 4.221, Ranking: 8/30) 5.
Yun-Ju Huang, Le-Xin Chrystal
Choong, Suraphan Panyod,
Yu-En Lin, HuaiSyuan
Huang, Kuan-Hung Lu, Wei-Kai Wu,
Lee-Yan Sheen (2021). Gastrodia elata Blume
water extract modulates neurotransmitters and alters the gut microbiota in a
mild social defeat stress-induced depression mouse model. Phytotherapy Research 35, 5133-5142. (SCI, IF: 6.388,
Ranking: 8/63) 6.
Yu-En
Lin, Yi-Chun Chen, Kuan-Hung Lu,
Yun-Ju Huang, Suraphan Panyod,
Wei-Ting Liu, Shu-Hui Yang, Yun-Sheng Lu, Mei-Hsing
Chen, Lee-Yan Sheen (2021). Antidepressant-like effects of water extract of Cordyceps militaris
(Linn.) Link by modulation of ROCK2/PTEN/Akt
signaling in an unpredictable chronic mild stress-induced animal model. Journal of Ethnopharmacology 276,
114194. (SCI, IF: 5.195, Ranking: 4/30) 7.
Yu-En
Lin, Hsiang-Lan Wang, Kuan-Hung Lu,
Yun-Ju Huang, Suraphan Panyod,
Wei-Ting Liu, Shu-Hui Yang, Mei-Hsing Chen,
Yun-Shen Lu, Lee-Yan Sheen (2021). Water extract of Armillaria mellea (Vahl)
P. Kumm. Alleviates the depression-like behaviors
in acute- and chronic mild stress-induced rodent models via anti-inflammatory
action. Journal
of Ethnopharmacology 265, 113395. (SCI, IF: 5.195, Ranking: 4/30) 8.
Kuan-Hung
Lu, Yi-Jyun
Sheen, Tsui-Ping Huang, Shu-Hui Kao, Chun-Lung Cheng, Cheng-An
Hwang, Shiowshuh Sheen, Lihan
Huang, Lee-Yan Sheen (2020). Effect of temperature on the growth of Staphylococcus aureus in ready-to-eat
cooked rice with pork floss. Food
Microbiology 89, 103374. (SCI, IF: 6.374, Ranking: 22/144) 9.
Kuan-Hung
Lu, Guan-Ling Ou,
Hui-Ping Chang, Wei-Cheng Chen, Shing-Hwa Liu,
Lee-Yan Sheen (2020). Safety evaluation of water extract of Gastrodia elata
Blume: Genotoxicity and 28-day oral toxicity studies. Regulatory Toxicology and Pharmacology 114, 104657. (SCI, IF: 3.598, Ranking: 3/17) 10. Yun-Ju Huang, Nai-Yuan
Hsu, Kuan-Hung Lu, Yu-En Lin, Shih-Hang Lin, Yun-Sheng Lu, Wei-Ting Liu, Mei-Hsing Chen, Lee-Yan Sheen (2020). Poria cocos water extract ameliorates the
behavioral deficits induced by unpredictable chronic mild stress in rats by
down-regulating inflammation. Journal
of Ethnopharmacology 258, 112566.
(SCI, IF: 5.195, Ranking: 4/30) 11. Suraphan Panyod, Wei-Kai
Wu, Kuan-Hung Lu, Chun-Ting Liu,
Yung-Lin Chu, Chi-Tang Ho, Wen Luan Wendy Hsiao, Ming-Shiang
Wu, Yi-Syuan Lai, Wei-Cheng Chen, Yu-En Lin, Shi-Hang Lin, Lee-Yan Sheen (2020). Allicin
modifies the composition and function of the gut microbiota in alcoholic
hepatic steatosis mice. Journal of
Agricultural and Food Chemistry
68, 3088-3098. (SCI, IF: 5.895, Ranking: 6/59) 12. Kuan-Hung Lu, Yi-Chun Pan, Lee-Yan Sheen (2020). Combination of cut-log cultivated fruiting
body and solid-state cultured mycelia of Taiwanofungus camphoratus
ameliorates CCl4-induced liver injury in rats. Journal of Traditional and Complementary
Medicine 10, 166-174.
(SCI, IF: 4.221, Ranking: 8/30) 13. Kuan-Hung Lu, Huey-Yin Lee, Yung-Lin Chu, Chi-Tang Ho, Lee-Yan Sheen (2019).
Bitter orange peel extract induces endoplasmic reticulum-mediated autophagy
in human hepatoma cells. Journal of
Functional Foods 60, 103404. (SCI, IF: 5.223, Ranking: 37/144) 14. Yun-Ju Huang, Kuan-Hung Lu, Yu-En Lin,
Suraphan Panyod, Hsin-Yu Wu, Wan-Ting Chang, Lee-Yan Sheen (2019). Garlic essential oil mediates acute and
chronic mild stress-induced depression in rats via modulation of
monoaminergic neurotransmission and brain-derived neurotrophic factor levels.
Food & Function 10, 8094-8105.
(SCI, IF: 6.317, Ranking: 24/144) 15. Yu-En Lin, Kuan-Hung Lu, Lee-Yan
Sheen (2018). Recent research progress on the
antidepressant-like effect and neuropharmacological potential of Gastrodia elata
Blume. Current Pharmacology Reports
4, 220-237. (SJR, Ranking: Q2) 16. Yu-En Lin,
Shao-Ting Chou, Shih-Hang Lin, Kuan-Hung
Lu, Suraphan Panyod,
Yi-Syuan Lai, Chi-Tang Ho, Lee-Yan Sheen (2018).
Antidepressant-like effects of water extract of Gastrodia elata Blume on neurotrophic regulation
in a chronic social defeat stress model. Journal
of Ethnopharmacology 215, 132-139. (SCI, IF: 5.195, Ranking: 4/30) 17. Hsiang-Ling Huang, Swee-Ling
Lim, Kuan-Hung Lu, Lee-Yan Sheen
(2018). Antidepressant-like effects of Gan-Mai-Dazao-Tang
via monoamine regulatory pathways on forced swimming test in rats. Journal of Traditional and Complementary
Medicine 8, 53-59. (SCI, IF: 4.221, Ranking: 8/30) 18. Kuan-Hung Lu, Ching-Yi Weng, Wei-Cheng Chen, Lee-Yan Sheen (2017). Ginseng
essence, a medicinal and edible herbal formulation, ameliorates carbon
tetrachloride-induced oxidative stress and liver injury in rats. Journal of Ginseng Research 41,
316-325. (SCI, IF: 5.735, Ranking:
3/30) 19. 盧冠宏，沈立言（2016）：〈藥食同源：臺灣藥食兩用中藥材之安全管理現況〉，《中國醫藥研究叢刊》31期，84-88。 20. Suraphan Panyod, Wei-Kai
Wu, Chi-Tang Ho, Kuan-Hung Lu,
Chun-Ting Liu, Yung-Lin Chu, Yi-Syuan Lai,
Wei-Cheng Chen, Yu-En Lin, Shi-Hang Lin, Lee-Yan
Sheen (2016). Diet supplementation with allicin protects against alcoholic
fatty liver disease in mice by improving anti-inflammation and antioxidative
functions. Journal of Agricultural and
Food Chemistry 64, 7104-7113. (SCI, IF: 5.895, Ranking: 6/59) 21. 盧冠宏，潘怡君，沈立言（2016）：〈臺灣食品安全事件的省思：從危機處理提升至風險管理〉，《中國飲食文化》12.1期，245-271。（THCI Core） 22. Yi-Syuan Lai,
Wan-Ching Lee, Yu-En Lin, Chi-Tang Ho, Kuan-Hung Lu, Shih-Hang Lin, Suraphan Panyod, Yung-Lin Chu,
Lee-Yan Sheen (2016). Ginger essential oil ameliorates hepatic injury and
lipid accumulation in high fat diet-induced nonalcoholic fatty liver disease.
Journal of Agricultural and Food
Chemistry 64, 2062-2071. (SCI, IF: 5.895, Ranking: 6/59) 23. Wei-Cheng Chen, Yi-Syuan
Lai, Shih-Hang Lin, Kuan-Hung Lu, Suraphan Panyod, Chi-Tang Ho,
Lee-Yan Sheen (2016). Anti-depressant effects of Gastrodia elata Blume and its compounds, gastrodin and 4-hydroxybenzyl alcohol, involve the
monoaminergic system and neuronal cytoskeletal remodeling processes. Journal of Ethnopharmacology 182,
190-199. (SCI, IF: 5.195, Ranking: 4/30) 24. Shih-Hang Lin, Mei-Ling Chou, Wei-Cheng Chen,
Yi-Syuan Lai, Kuan-Hung
Lu, Cherng-Wei Hao, Lee-Yan Sheen (2015). A
medicinal herb, Melissa officinalis
L. ameliorates depressive-like behavior of rats in the forced swimming test
via regulating the serotonergic neurotransmitter. Journal of Ethnopharmacology 175, 266-272. (SCI, IF: 5.195,
Ranking: 4/30) 25. Yi-Syuan Lai,
Wei-Cheng Chen, Tien-Chueh Kuo,
Chi-Tang Ho, Ching-Hua Kuo, Yufeng
J. Tseng, Kuan-Hung Lu, Shih-Hang
Lin, Suraphan Panyod,
Lee-Yan Sheen (2015). Mass-spectrometry-based serum metabolomics of a
C57BL/6J mouse model of high-fat-diet-induced non-alcoholic fatty liver
disease development. Journal of
Agricultural and Food Chemistry 63, 7873-7884. (SCI, IF: 5.895, Ranking:
6/59) 26. Wei-Cheng Chen, Yi-Syuan
Lai, Kuan-Hung Lu, Shih-Hang Lin,
Li-Yun Liao, Lee-Yan Sheen (2015). Method development and validation for the
HPLC assay of gastrodin in water extracts from
different sources of Gastrodia elata Blume.
Journal of Food and Drug Analysis
23, 803-810. (SCI, IF: 6.157, Ranking: 27/144) 27. 盧冠宏，沈立言（2015）：〈面對食安風暴，民眾該如何自保〉，《司法新聲》113期，25 - 29。 28. Kuan-Hung Lu, Hui-Chun Tseng, Chun-Ting Liu, Ching-Jang Huang, Jong-Ho Chyuan, Lee-Yan Sheen (2014). Wild bitter gourd protects
against alcoholic fatty liver in mice by attenuating oxidative stress and
inflammatory responses. Food &
Function 5: 1027-1037. (SCI, IF: 6.317, Ranking: 24/144) 29. Shih-Hang Lin, Wei-Cheng Chen, Kuan-Hung Lu, Pei-Ju Chen, Shu-Chen Hsieh,
Tzu-Ming Pan, Shui-Tein Chen, Lee-Yan Sheen (2014).
Down-regulation of Slit-Robo pathway mediating neuronal cytoskeletal
remodeling processes facilitates the antidepressive-like
activity of Gastrodia elata Blume.
Journal of Agricultural and Food
Chemistry 62: 10493-10503. (SCI, IF: 5.895, Ranking: 6/59) 30. Yi-Syuan Lai,
Wei-Cheng Chen, Chi-Tang Ho, Kuan-Hung Lu,
Shih-Hang Lin, Hui-Chun Tseng, Lee-Yan Sheen (2014). Garlic essential oil
protects against obesity-triggered nonalcoholic fatty liver disease through
modulation of lipid metabolism and oxidative stress. Journal of Agricultural and Food Chemistry 62: 5897-5906. (SCI,
IF: 5.895, Ranking: 6/59) 31. Yung-Lin Chu, Raghu Rajasekaran,
Kuan-Hung Lu, Chun-Ting Liu, Shu-Hsi Lin, Yi-Syuan Lai,
Wei-Cheng Cheng, Shih-Hang Lin, Lee-Yan Sheen (2013). Autophagy therapeutic
potential of garlic in human cancer therapy. Journal of Traditional and Complementary Medicine 3: 159-162.
(SCI, IF: 4.221, Ranking: 8/30) 32. Kuan-Hung Lu, Hui-Ju Lee, Min-Li Huang, Shang-Chih
Lai, Yu-Ling Ho, Yuan-Shiun Chang, Chin-Wen Chi
(2012). Synergistic apoptosis-inducing antileukemic effects of arsenic
trioxide and Mucuna macrocarpa stem
extract in human leukemic cells via a reactive oxygen species-dependent
mechanism. Evidence-Based Complementary
and Alternative Medicine, vol. 2012, Article ID 921430. (SCI, IF: 2.650,
Ranking: 16/30) 33. Kuan-Hung Lu, Chun-Ting Liu, Raghu Rajasekaran,
Lee-Yan Sheen (2012): Therapeutic potential of Chinese herbal medicines in
alcoholic liver disease. Journal of
Traditional and Complementary Medicine 2: 115-122. (SCI, IF: 4.221,
Ranking: 8/30) 34. Raghu Rajasekaran, Kuan-Hung Lu,
Lee-Yan Sheen (2012). Recent research progress on garlic
(大蒜dàsuàn) as a potential anticarcinogenic
agent against major digestive cancers. Journal
of Traditional and Complementary Medicine 2: 192-201. (SCI, IF: 4.221,
Ranking: 8/30) 35. Yen-Wenn Liu, Kuan-Hung Lu, Chi-Tang Ho, Lee-Yan Sheen
(2012). Protective effects of Antrodia cinnamomea on liver injury. Journal of Traditional and Complementary Medicine 2: 284-294.
(SCI, IF: 4.221, Ranking: 8/30) 36. Kuan-Hung Lu, Yuh-Fang Chang, Pen-Hui Yin,
Ting-Ting Chen, Yu-Ling Ho, Yuan-Shiun Chang, Chin-Wen
Chi (2010). In vitro and in vivo apoptosis-inducing antileukemic effects of Mucuna macrocarpa stem
extract on HL-60 human leukemia cells. Integrative
Cancer Therapies 9: 298-308. (SCI, IF: 3.077, Ranking: 13/30) 37. Kuan-Hung Lu*, Ching-Yuan Chen, Ru-Liang Shih, Fwu-Show
Chin, Chun-Sheng Chien (2008). Method development
and validation for the GC-FID assay of ethanol in reservoir-type fentanyl
transdermal patches. Journal of Food
and Drug Analysis 16: 1-7. (SCI, IF: 6.157, Ranking: 27/144)
*corresponding author (B) 專書論文 1.
盧冠宏、沈立言（2022）。〈美國食品安全現代化法案 (FSMA) 與食安管理之預防性控制〉。載於詹富智、王苑春、林金源（主編），《食安管理與產業發展》（第15章，頁295-316）。臺中市：國立中興大學。 2.
盧冠宏、沈立言（2018）。〈國家認證之健康食品與預防醫學〉。載於洪冠予（主編），《醫用營養學》（第19章，頁447-466）。臺北市：國立臺灣大學醫學院。 3.
沈立言、盧冠宏（2018）。〈食品安全及風險分析概論〉，載於沈立言、汪曉琪、宋威徹、盧冠宏（主編），《食品安全與衛生》（第1章，頁1-24）。新北市：國立空中大學。 4.
盧冠宏（2018）。〈食品毒理與安全性評估〉，載於沈立言、汪曉琪、宋威徹、盧冠宏（主編），《食品安全與衛生》（第10章，頁235-259）。新北市：國立空中大學。 5.
盧冠宏（2018）。〈認識食品與藥物交互作用〉，載於沈立言、汪曉琪、宋威徹、盧冠宏（主編），《食品安全與衛生》（第11章，頁261-284）。新北市：國立空中大學。 6.
Chun-Ting Liu, Kuan-Hung
Lu, Meaghan Tobin, and Lee-Yan Sheen (2016). Chinese Dates (Jujubes): A
Traditional Functional Food. Chapter 14 in “Chinese Dates” edited by Donghong Liu, Xingqian Ye, and Yueming Jiang,
p.p. 267-280, CRC Press, FL, USA. |
|
(C) 研討會論文 |
|
1.
Liu-Yean Goh, Kuan-Hung
Lu* (2023). Prevalence of phylotypes and virulence factors of uropathogenic Escherichia
coli in freshly prepared beverages vended in Taiwan. 12th International
Conference on Predictive Modelling in Food (ICPMF12), June 13-16, Sapporo,
Japan. 2.
Chun-Yi Kang, Kuan-Hung
Lu* (2023). Hazard identification of bacterial uropathogens
in retail meats: the prevalence of uropathogenic Escherichia coli in ready-to-eat
chicken and pork in Taiwan. 12th International Conference on Predictive
Modelling in Food (ICPMF12), June 13-16, Sapporo, Japan. 3.
Tzu-Ping Kao, Kuan-Hung
Lu* (2023). Predictive models for the growth of uropathogenic
Escherichia coli in raw and cooked
beef as a function of temperature. 12th International Conference on
Predictive Modelling in Food (ICPMF12), June 13-16, Sapporo, Japan. 4.
Yun-Jung Lee, Kuan-Hung
Lu* (2022). Emerging foodborne urinary tract infection: The prevalence
and survival modeling of uropathogenic Escherichia coli in chicken meat in
Taiwan. 2022臺灣風險分析學會年會暨研討會, March 23, Taipei, Taiwan.《本論文榮獲海報論文發表競賽第一名》 5.
Tzu-Ping Kao, Kuan-Hung
Lu* (2022). Emerging foodborne pathogens: The prevalence and growth
modeling of uropathogenic Escherichia coli in raw beef in Taiwan. 2022臺灣風險分析學會年會暨研討會, March 23, Taipei, Taiwan.《本論文榮獲海報論文發表競賽第二名》 6.
Hui-Erh
Chai, Kuan-Hung Lu, Tsui-Ping Huang, Chun-Lung Cheng, Lihan
Huang, Cheng-An Hwang, Shiowshuh
Sheen, Lee-Yan Sheen (2019). Microbiological risk assessment of Staphylococcus aureus in ready-to-eat
lettuce in Taiwan. International Association for Food Protection Annual Meeting
(IAFP 2019), July 21-24, Louisville, Kentucky, USA. 7.
Guang-Ling Ou,
Kuan-Hung Lu, Hui-Ping Chang, Lee-Yan
Sheen (2018). Safety evaluation of the water extract of Gastrodia elata Blume, 17th Meeting of
Consortium for Globalization of Chinese Medicine, August 8-10, Kuching,
Malaysia. 8.
Hui-Erh
Chai, Kuan-Hung Lu, Tsui-Ping Huang, Chun-Lung Cheng, Lihan
Huang, Cheng-An Hwang, Shiowshuh
Sheen, Lee-Yan Sheen (2018). Modeling the effect of temperature on the growth
of Staphylococcus aureus in
fresh-cut lettuce. International Association for Food Protection Annual
Meeting (IAFP 2018), July 8-11, Salt Lake City, Utah, USA. 9.
Guan-Ling Ou,
Shing-Hwa Liu, Fu-Chuo Peng, Kuan-Hung
Lu, Lee-Yan Sheen (2018). Antidepressant-like of water extract of Gastrodia eleta Blume
(Tian-ma) and its safety evaluation. 8th International Congress of Asian
Society of Toxicology, June 17-20, Pattaya, Thailand. 10. Hui-Erh Chai, Kuan-Hung Lu, Tsui-Ping
Huang, Lee-Yan Sheen (2018). Preliminary study of the temperature effect on Staphylococcal enterotoxins production
in leafy salad, a popular ready-to-eat food in Taiwan. International
Conference on Functional Food for Improving Sarcopenia, Cachexia and Frailty.
March 2, Taipei, Taiwan. 11. Yi-Chun Chen, Kuan-Hung
Lu, Mei-Hsing Chen, Yun-Sheng Lue, Lee-Yan
Sheen (2017). Water extract of Cordyceps
militaris may reverse depression-like behavior
in chronic unpredictable mild stress rats model via
regulating ROCK2/Akt pathway. The 32nd
International Symposium on Natural Products, October 13-14, Taichung, Taiwan.《本篇榮獲論文競賽傳統中藥組優等獎》 12. Xiao-Ting Lu, Kuan-Hung
Lu*, Chen-Kai Liao, Fei-Pei Lai, Ming-Shiang
Wu, Lee-Yan Sheen (2016). Immediate changes of meridian energy and personal
feelings after ginger tea and coconut water consumption by young subjects
with hot constitution. 15th Meeting of Consortium for Globalization of
Chinese Medicine, August 22-25, Taipei, Taiwan. *Invited Speaker in
Preventive Medicine session 13. Yi-Jyun Sheen, Kuan-Hung Lu, Tsui-Ping
Huang, Cheng-Chun Chou, Hsien-Wen Kuo, Chun-Lung
Cheng, Lihan Huang, Cheng-An
Hwang, Shiowshuh Sheen, Lee-Yan Sheen (2016).
Applying predictive microbiology and microbial risk assessment to assess the
risk of ready-to-eat food products in Taiwan based on consumption habits.
International Association for Food Protection Annual Meeting (IAFP 2016),
July 31 - August 3, St. Louis, Missouri, USA. 14. Wei-Cheng Chen, Kuan-Hung
Lu, Chi-Tang Ho, Chia-Chi Huang, Lee-Yan Sheen. (2016). Development of a
rapid microscopic Raman spectroscopic screening method to determine Gastrodia elata Blume
varieties. The Fourth Taiwan International Symposium on Raman Spectroscopy,
June 29-30, Taipei, Taiwan. 15. Xiao-Ting Lu, Kuan-Hung
Lu, Chen-Kai Liao, Fei-Pei Lai, Ming-Shiang Wu,
and Lee-Yan Sheen (2015). Meridian energy analysis of immediate effects of
coconut water and ginger tea consumption in healthy subjects with cool/cold
and warm/hot constitutions. International Conference of Traditional and
Complementary Medicine on Health (ICTCMH 2015), October 24-27, Taipei,
Taiwan. 16. Tsui-Ping Huang, Chun-Lung Cheng, Yu-Ting Wang, Kuan-Hung Lu, and Lee-Yan Sheen (2015).
Evaluation of microbial risks for certified agricultural standards-compliant
ready-to-eat food products in Taiwan (2010-2014). International Association
for Food Protection Annual Meeting (IAFP 2015), July 25-28, Portland, Oregon,
USA. 17. Suraphan Panyod, Wei-Kai
Wu, Chi-Tang Ho, Tong-Rong Jan, Chun-Ting Liu, Kuan-Hung
Lu, Yung-Lin Chu, and Lee-Yan Sheen (2015). Dietary allicin: Its
potential liver protective activity against alcoholic fatty liver disease and
its impact on gut microbiota. Institute of Food Technologist Annual Meeting
& Food Expo (IFT15), July 11-14, Chicago, Illinois, USA. 18. Wei-Cheng Chen, Yi-Syuan
Lai, Shih-Hang Lin, Ying-Yu Chou, Kuan-Hung
Lu, Chi-Tang Ho, and Lee-Yan Sheen (2015). The molecular mechanism of the
anti-depressive effects exerted by gastrodin and
4-hydroxybenzyl alcohol, the active compounds of Gastrodia elata Blume. Institute of Food
Technologist Annual Meeting & Food Expo (IFT15), July 11-14, Chicago,
Illinois, USA. 19. 盧冠宏，沈立言（2015）：當前台灣食安問題總檢討。食品安全論壇，7月4-5日，桃園，臺灣。 20. Kuan-Hung Lu and Lee-Yan Sheen (2015). Key trends in functional foods. 2015
Asia Food & Beverage Summit, May 18-19, Bangkok, Thailand. 21. Yung-Lin Chu, Kuan-Hung
Lu, and Lee-Yan Sheen (2015). The unique medicinal mushroom, Antrodia cinnamomea,
with great potential on anti-liver cancer in Taiwan. 2015 SNUCRI Cancer
Symposium, April 1-4, Hwasun Kumho Resort, Korea. 22. Yi-Chun Pan, Jin-Ru
Huang, and Kuan-Hung Lu* (2014).
Anti-inflammatory effect of Mucuna macrocarpa stem extract on 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced ear edema in
mice. 台灣食品科學技術學會年會, December 5, Kaohsiung, Taiwan. *corresponding author 23. Yi-Chun Pan, Jin-Ru
Huang, and Kuan-Hung Lu* (2013).
Evaluation of anti-inflammatory activity of Mucuna macrocarpa stem extract on acute
cutaneous inflammation. Food &
Function International Symposium, November 25, Taichung, Taiwan.
*corresponding author 24. Wei-Cheng Chen, Kuan-Hung
Lu, and Lee-Yan Sheen (2013). Determination of gastrodin
in water extracts from different sources of Gastrodia elata Bl. by a validated HPLC method.
International Conference and Exhibition on Nutraceuticals and Food Functions
2013, November 5-9, Taipei, Taiwan. 25. Hui-Chun Tseng, Kuan-Hung
Lu, Chun-Ting Liu, and Lee-Yan Sheen (2013). Bitter melon ethanol
extracts ameliorate alcoholic fatty liver in mice by attenuating oxidative
stress andinflammatory response. The 3rd
Asia Pacific International Conference on Food Safety, October 29 - November
1, Taipei, Taiwan. 26. Ching-Yi Weng, Kuan-Hung
Lu, and Lee-Yan Sheen (2013). Protective effects of ginseng essence on
CCl4-induced oxidative stress and liver injury in rats. 2nd
Annual Meeting of the Good Practice in TCM Research Association, August 30,
Graz, Austria. 27. Yi-Chun Pan, Hsin-Tien
Cheng, Kuan-Hung Lu, and Rong-Huei Chen (2013). The skin-whitening and anti-aging
efficacy of cosmetic cream products containing Hesperethusa crenulata (Roxb.) Roem extracts on humans.
2013年醫護與健康科技研討會, May 31, Yilan, Taiwan.《本篇榮獲論文競賽壁報展示組第一名》 28. Yi-Chun Pan, Kuan-Hung
Lu, and Rong-Huei Chen (2013). Evaluation of
anti-aging and whitening efficacy of Hesperethusa crenulata (Roxb.) Roemstem bark and heart wood extracts. International
Conference of Traditional and Complementary Medicine on Health 2013, May
24-26, Taipei, Taiwan. 29. Wei-Cheng Chen, Kuan-Hung
Lu, and Lee-Yan Sheen (2013). Development and validation of a RP-HPLC
method for the determination of gastrodin in water
extracts of Gastrodiaelata
Bl. 台灣保健食品學會2013年會員大會暨長壽與享瘦研討會, March 8, Taichung, Taiwan. 30. 沈立言，盧冠宏，楊雀戀，羅明宇，吳明賢，李宛靜，周映妤（2012）：食物屬性對於不同體質健康人之脈波與歸經變化之研究。2012健康科學與生活研討會，12月29日，臺北，臺灣。 31. Chun-Ting Liu, Raghu Rajasekaran,
Kuan-Hung Lu, and Lee-Yan Sheen
(2012). Metabolomics of garlic and its active compounds on alcoholic fatty
liver disease in mice. International Conference and Exhibition on
Nutraceuticals and Food Functions 2012, December 1-6, Hawaii, USA. 32. Chin-Wen Chi, Kuan-Hung
Lu, Yuh-Fang Chang, Pen-Hui Yin, Ting-Ting
Chen, Yu-Ling Ho, and Yuan-Shiun Chang (2010). The
antiproliferative effects of Mucuna macrocarpa stem extract on HL-60 leukemia cells. AACR
101st Annual Meeting, April 17-21, Washington DC, USA. 33. Kuan-Hung Lu, Ching-Yuan Chen, Jun-Ming Hu, Hui-Chuan
Shih, Ru-Liang Shih, Fwu-Show Chin, and Chun-Sheng Chien (2006). Development and validation for the
simultaneous determination of ethanol content and organic volatile impurities
in reservoir-type fentanyl transdermal delivery system by gas chromatography.
66th International Congress of FIP, August 25-31, Salvador, Bahia,
Brazil. 34. Kuan-Hung Lu, Ching-Yuan Chen, Ru-Liang Shih, and Fwu-Show
Chin (2006). Development and validation of a RP-HPLC method for the
determination of MDMA in “Ecstasy” tablets. 2006台灣藥學會年會暨學術研討會, December 23, Taichung, Taiwan. 35. Kuan-Hung Lu, Ching-Yuan Chen, Jun-Ming Hu, Hui-Chuan
Shih, Ru-Liang Shih, and Fwu-Show Chin (2005).
Development and validation for the GC-FID assay of ethanol in reservoir-type
fentanyl transdermal delivery system. 九十四年度中國藥學會年會暨學術研討會, December 17-18, Kaohsiung, Taiwan. 36. Ching-Yuan Chen, Kuan-Hung
Lu, Hui-Chuan Shih, and Ru-Liang Shih (2005).
Determination of morphine in opium tincture and opium powder by high
performance liquid chromatography. 九十四年度中國藥學會年會暨學術研討會, December 17-18, Kaohsiung, Taiwan. |