學院	醫學院
系所	職能治療學系
題名	Three ways to improve arm function in the chronic phase after stroke by robotic priming combined with mirror therapy, arm training and movement-oriented therapy.
作者	Li, Y-C., Lin, K-C.*, Chen, C-L., Yao, G., Chang, Y-J., Lee, Y-Y., Liu, C-T., & Chen, W-S.
期刊名稱	Archives of Physical Medicine and Rehabilitation
發表日期	2023
著作性質	原著
語文	英文
關鍵字	Robotics, priming, mirror therapy, bilateral arm training, movement-oriented training, stroke
摘要	Background: Priming is an implicit learning technique that prepares the brain for a more plastic response, thereby leading to improved outcomes. This study aimed to examine the effects of bilateral robotic priming combined with mirror therapy (R-mirr) versus bilateral robotic priming combined with bilateral arm training (R-bilat), relative to the control approach of bilateral robotic priming combined with movement-oriented training (R-mov) in patients with stroke. Methods: A single-blind, preliminary, randomized controlled trial. Four outpatient rehabilitation settings. Outpatients with stroke and mild to moderate motor impairment (N = 63). Patients received 6 weeks of clinic-based R-mirr, R-bilat, or R-mov for 90 minutes/day, 3 days/week, plus a transfer package at home for 5 days/week. Fugl-Meyer Assessment upper extremity subscale (FMA-UE), ABILHAND, and Stroke Impact Scale (SIS) version 3.0 scores before, immediately after, and 3 months after treatment as well as the lateral pinch strength and the accelerometry before and immediately after treatment. Results: The posttest results favored R-mirr over R-bilat and R-mov on the FMA-UE score (P<.05). Follow-up analysis revealed that significant improvement in FMA-UE score was retained at the 3-month follow-up in the R-mirr over R-bilat or R-mov (P<.05). Significant improvements were not observed in the R-mirr over R-bilat and R-mov on other outcomes. Conclusions: Between-groups differences were only detected for the primary outcome – 5 FMA-UE. That was R-mirr was more effective at enhancing upper-limb motor improvement, 6 and the effect has the potential to be maintained at 3 months of follow-up.