學院 |
醫學院 |
系所 |
職能治療學系 |
題名 |
Validity,
responsiveness, and minimal clinically important difference of EQ-5D-5L in
stroke patients undergoing rehabilitation |
作者 |
Chen, P-Y.†, Lin, K-C.†, Liing, R-J., Wu, C-Y.*,
Chen, C-L., & Chang, K-C. |
期刊名稱 |
Quality of Life Research(SCI-Indexed) |
發表日期 |
2015 |
著作性質 |
原著 |
語文 |
英文 |
關鍵字 |
stroke, quality of life, rehabilitation,
validity, MCID, EQ-5D-5L |
摘要 |
Purpose To examine the criterion validity, responsiveness,
and minimal clinically important difference (MCID) of the EuroQoL
5-Dimensions Questionnaire (EQ-5D-5L) and visual analog scale (EQ-VAS) in
people receiving rehabilitation after stroke. Methods The EQ-5D-5L, along with four criterion
measures—the Medical Research Council scales for muscle strength, the
Fugl-Meyer Assessment, the Functional Independence Measure, and the Stroke
Impact Scale—were administered to 65 patients with stroke before and after 3
to 4 weeks therapy. Criterion validity was estimated using the Spearman
correlation coefficient. Responsiveness was analyzed by the effect size (ES),
standardized response mean (SRM), and criterion responsiveness. The MCID was
determined by anchor-based and distribution-based approaches. The percentage
of patients exceeding the MCID was also reported. Results Concurrent validity of the EQ-Index was
better compared with the EQ-VAS. The EQ-Index has better power for predicting
the rehabilitation outcome in the activities of daily living than other motor-related
outcome measures. The EQ-Index was moderately responsive to change (SRM =
0.63), whereas the EQ-VAS was only mildly responsive to change. The MCID
estimation of the EQ-Index (the percentage of patients exceeding the MCID)
was 0.10 (33.8%) and 0.10 (33.8%) based on the anchor-based and
distribution-based approaches, respectively, and the estimation of EQ-VAS was
8.61 (41.5%) and 10.82 (32.3%). Conclusions The EQ-Index has shown reasonable
concurrent validity, limited predictive validity, and acceptable
responsiveness for detecting the health-related quality of life in stroke
patients undergoing rehabilitation, but not for EQ-VAS. Future research
considering different recovery stages after stroke is warranted to validate
these estimations. |