學院 |
醫學院 |
系所 |
職能治療學系 |
題名 |
Changes
in structural integrity are correlated with motor and functional recovery after
post-stroke rehabilitation |
作者 |
Fan, Y-T.†
, Lin, K-C.†,
Liu, H-L., Chen, Y-L., & Wu, C-Y.* |
期刊名稱 |
Restorative
Neurology and Neuroscience(SCI-Indexed) |
發表日期 |
2015 |
著作性質 |
原著 |
語文 |
英文 |
關鍵字 |
diffusion tensor imaging, corticospinal tract,
transcallosal motor tracts, motor recovery, stroke, rehabilitation |
摘要 |
Purpose: Diffusion tensor imaging (DTI) studies indicate the structural
integrity of the ipsilesional corticospinal tract (CST) and the transcallosal
motor tract, which are closely linked to stroke recovery. However, the
individual contribution of these 2 fibers on different levels of outcomes
remains unclear. Here, we used DTI tractography to investigate whether
structural changes of the ipsilesional CST and the transcallosal motor tracts
associate with motor and functional recovery after stroke rehabilitation. Methods: Ten participants with post-acute stroke were evaluated with the Fugl-Meyer
Assessment (FMA), the Wolf Motor Function Test (WMFT), the Functional
Independence Measure (FIM), and DTI before and after bilateral robotic
training. Results: All participants had marked improvements in motor performance,
functional use of the affected arm, and independence in daily activities.
Increased fractional anisotropy (FA) in the ipsilesional CST and the
transcallosal motor tracts was noted from pre-treatment to the end of
treatment. Participants with higher pre-to-post differences in FA values of
the transcallosal motor tracts had greater gains in the WMFT and the FIM
scores. A greater improvement on the FMA was coupled with increased FA
changes along the ipsilesional CST. Conclusions: These findings suggest 2 different structural indicators for
post-stroke recovery separately at the impairment-based and function-based
levels. |