學院

醫學院

系所

職能治療學系

題名

Relevant factors to instrumental activities of daily living in people with Alzheimier’s disease

作者

Kuo, Y-C., Pai, M-C., Wang, T-Y.*, Ma, H-I., & Lin, K-C.

期刊名稱

Journal of Taiwan Occupational Therapy Association

發表日期

2013

著作性質

原著

語文

中文

關鍵字

Alzheimier’s disease, visuospatial  memory, declarative memory, instrumental activity of daily living.

摘要

UPATIONAL THERAPY

During the progression of Alzheimer’s disease (AD), memory impairment is one of the major cognitive symptoms for people in the early stage of AD. The memory dysfunction is an important factor for the functional impairment which contributes to the caregiver burden and the decision for institutionalization of the patient. This study was to investigate the relationship between memory function and instrumental activities of daily living (IADL), while accounting for demographic and general cognitive measure, MMSE. Thirty-nine subjects with mild AD were included in this study. A multiple regression model with stepwise method was used to assess the relationship between different memory domains and IADL. Using stepwise regression analysis for the relationship between memory functions (episodic, semantic, objects, and visuaospatial domains) and IADL confirmed the visuaospatial memory by Route Map Recall Test as the only predictor of IADL in the model (R2 = .46, p < .001). _ e results suggested that the visuospatial memory related to the executive control of attention is a key contributor to the impairment in IADL, gender and age were the second and the third significant predictors. _ e three factors explained a total of 64.4% of the variance (p < .001) for IADL. The findings have clinical implications to the interventions in preserving IADL function for the patients with AD.