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Yu, Chung-Jen Research Assistant 2011.02 - 2011.10 |
1. Topic: Identification of Novel Antibacterial Agent against Methicillin-Resistant Staphylococcus aureus |
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Chen, Yi-Ru Master student 2011.07 - 2013.07 |
1. Thesis: Development of Novel Small-Molecule Agents against Staphylococcus aureus 2. Hao-Chieh Chiu, Su-Lin Lee, Naval Kapuriya, Dasheng Wang, Yi-Ru Chen, Sung-Liang Yu, Samuel K. Kulp, Lee-Jene Teng, Ching-Shih Chen* (2012 Aug) Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. 20(15):4653-60. (SCI) 3. Shiou-Ru Tzeng, Yi-Wei Huang, Yao-Qing Zhang, Ching-Yi Yang, Han-Sheng Chien, Yi-Ru Chen, Sung-Liang Yu, Ching S. Chen, Hao-Chieh Chiu* (2020 Dec) A Celecoxib Derivative Eradicates Antibiotic-Resistant Staphylococcus aureus and Biofilms by Targeting YidC2 Translocase. International Journal of Molecular Sciences. DOI: 10.3390/ijms21239312 |
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Lo, Jung-Hsin Master Student 2012.08 - 2014.07 |
1. Thesis: Evaluation of a Host-Directed Antimicrobial Drug AR-12 Against Intracellular Bacterial Infection 2. Jung-Hsin Lo, Samuel K Kulp, Ching-Shih Chen, Hao-Chieh Chiu* (2014 Dec) Sensitization of Intracellular Salmonella to Aminoglycosides in vitro and in vivo by a Host-Targeted Antimicrobial Agent. Antimicrobial Agents and Chemotherapy. 58(12):7375-82. (SCI) 3. Outstanding Research Paper Award, College of Medicine, NTU, 2015. 4. Research Paper Award, Department of Clinical Laboratory Sciences and Medical Biotechnology, 2015. |
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Chang, Han-Chu Master Student 2013.07 - 2015.07 |
1. Thesis: Investigation of a Novel Antibacterial Agent SC-5005 against Staphylococcus aureus 2. Outstanding Poster Award, The 21th General Meeting, Taiwan Society of Microbiology, 2014 Dec. 3. Han-Chu Chang, Yu-Ting Huang, Chang-Shi Chen, Yi-Wei Chen, Yu-Tsung Huang, Jung-Chen Su, Lee-Jeng Teng, Chung-Wai Shiau, Hao-Chieh Chiu* (2016 Feb.) In Vitro and In Vivo Activity of a Novel Sorafenib Derivative SC5005 against Methicillin-Resistant Staphylococcus aureus. Journal of Antimicrobial Chemotherapy. 71(2):449-59. (SCI) 4. Outstanding Research Paper Award, College of Medicine, NTU, 2016 Apr. 5. Research Paper Award, Department of Clinical Laboratory Sciences and Medical Biotechnology, NTU, 2016. 6. Chieh-Hsien Lu, Chung-Wai Shiau, Yung-Chi Chang, Hsiu-Ni Kung, Jui-Ching Wu, Chui-Hian Lim, Hui-Hui Yeo, Han-Chu Chang, Han-Sheng Chien, Sheng-Hsuan Huang, Wei-Kang Hung, Jun-Rong Wei, Hao-Chieh Chiu* (2021 Apr) SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance. Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkab114 (SCI) |
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Huang, Sheng-Hsuan Master Student 2014.08 - 2016.07 |
1. Thesis: Investigate the mechanism of action of a novel anti-Staphylococcal agent SC-5005 2. Chieh-Hsien Lu, Chung-Wai Shiau, Yung-Chi Chang, Hsiu-Ni Kung, Jui-Ching Wu, Chui-Hian Lim, Hui-Hui Yeo, Han-Chu Chang, Han-Sheng Chien, Sheng-Hsuan Huang, Wei-Kang Hung, Jun-Rong Wei, Hao-Chieh Chiu* (2021 Apr) SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance. Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkab114 (SCI) |
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Chen, Hui-Yi Research Assistant 2014.09 - 2015.07 |
1. Topic: Identification of host factors involved in Shiga-like toxins induced cell death |
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Su, Jung-Chen Postdoctoral Researcher 2014.12 - 2016.07 |
1. Jung-Chen Su, Ai-Chung Mar, Szu-Hsien Wu, Wei-Tien Tai, Pei-Yi Chu, Chia-Yun Wu, Ling-Ming Tseng, Te-Chang Lee, Kuen-Feng Chen, Chun-Yu Liu, Hao-Chieh Chiu*, Chung-Wai Shiau* (2016 Jul) Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis. Scientific Reports. 1; 6:28888. (SCI) 2. Jung-Chen Su, Yu-Ting Huang, Chang-Shi Chen, Hao-Chieh Chiu*, Chung-Wai Shiau* (2018 Jan) Design and synthesis of malonamide derivatives as antibiotics against methicillin-resistant Staphylococcus aureus. Molecules. 23(1), 27. (SCI) |
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Yuan, Chia-Min Master Student 2015.09 - 2017.07 |
1. Thesis: Investigate the mode of action of SC-5005, and the synergistic effect of SC5005 with nature products against methicillin-resistant Staphylococcus aureus 2. Travel Award, ASM conference on Antibacterial Development, American Society of Microbiology, 2016 Dec. |
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Yang, Ching-Yi Master Student 2015.09 - 2017.06 |
1. Thesis: Repurposing an antipsychotic drug, loxapine, as a host-targeting antibacterial agent against Salmonella Typhimurium infection 2. Ching-Yi Yang#, Cheng-Yun Hsu#, Chun-Sheng Fang, Chung-Wai Shiau, Ching S. Chen, Hao-Chieh Chiu* (2019 Aug) Loxapine, an antipsychotic drug, suppresses intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages. Journal of Microbiology, Immunology and Infection. 52(4):638-647 (SCI) (#Equal Contribution) 3. Shiou-Ru Tzeng, Yi-Wei Huang, Yao-Qing Zhang, Ching-Yi Yang, Han-Sheng Chien, Yi-Ru Chen, Sung-Liang Yu, Ching S. Chen, Hao-Chieh Chiu* (2020 Dec) A Celecoxib Derivative Eradicates Antibiotic-Resistant Staphylococcus aureus and Biofilms by Targeting YidC2 Translocase. International Journal of Molecular Sciences. DOI: 10.3390/ijms21239312 |
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Chiu, Chia-I Master Student 2016.09 - 2018.08 |
1. Thesis: Evaluation of Host-Directed Anti-Bacterial Agents Against Intracellular Salmonella Typhimurium 2. Travel Award, ASM conference on Antibacterial Development, American Society of Microbiology, 2017 Sep. |
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Lim, Chui-Hian Master Student 2016.09 - 2018.06 |
1. Thesis: A New Membrane Targeting Compound, SC-5005, Shows Synergistic Bactericidal Activity with Certain Natural Products Against Methicillin-Resistant Staphylococcus aureus 2. Chieh-Hsien Lu, Chung-Wai Shiau, Yung-Chi Chang, Hsiu-Ni Kung, Jui-Ching Wu, Chui-Hian Lim, Hui-Hui Yeo, Han-Chu Chang, Han-Sheng Chien, Sheng-Hsuan Huang, Wei-Kang Hung, Jun-Rong Wei, Hao-Chieh Chiu* (2021 Apr) SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance. Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkab114 (SCI) |
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Hung, Wei-Kang Master Student 2017.09 - 2019.01 |
1. Chieh-Hsien Lu, Chung-Wai Shiau, Yung-Chi Chang, Hsiu-Ni Kung, Jui-Ching Wu, Chui-Hian Lim, Hui-Hui Yeo, Han-Chu Chang, Han-Sheng Chien, Sheng-Hsuan Huang, Wei-Kang Hung, Jun-Rong Wei, Hao-Chieh Chiu* (2021 Apr) SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance. Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkab114 (SCI) |
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Huang, Yi-Wei Postdoctoral Researcher 2018.08 - 2020.05 |
1. Shiou-Ru Tzeng#, Yi-Wei Huang#, Yao-Qing Zhang, Ching-Yi Yang, Han-Sheng Chien, Yi-Ru Chen, Sung-Liang Yu, Ching S. Chen, Hao-Chieh Chiu* (2020 Dec) A Celecoxib Derivative Eradicates Antibiotic-Resistant Staphylococcus aureus and Biofilms by Targeting YidC2 Translocase. International Journal of Molecular Sciences. DOI: 10.3390/ijms21239312 (#Equal Contribution) |
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Hsu, Cheng-Yun Master Student 2018.09 - 2020.08 |
1. Thesis: Novel Dibenzoxazepines Attenuate the Efflux Pump-Mediated Resistance to Oxidative Stresses of Intra-macrophagic Salmonella 2. Ching-Yi Yang#, Cheng-Yun Hsu#, Chun-Sheng Fang, Chung-Wai Shiau, Ching S. Chen, Hao-Chieh Chiu* (2019 Aug) Loxapine, an antipsychotic drug, suppresses intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages. Journal of Microbiology, Immunology and Infection. 52(4):638-647 (SCI) (#Equal Contribution) 3. Outstanding Poster Award, The 23th General Meeting, Taiwan Society of Microbiology, 2019 Nov. 4. Research Paper Award, Department of Clinical Laboratory Sciences and Medical Biotechnology, NTU, 2019. |
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Chou, Shih-Hsiu Master Student 2018.09 - 2020.08 |
1. Thesis: Repurposing the Tyrosine Kinase Inhibitor to Develop Novel Antibacterial Agents against Drug-resistant Salmonella Typhimurium in Macrophages |
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Lu, Chieh-Sien Master Student 2018.09 - 2020.08 |
1. Thesis: The synergistic mechanism of SC5005 and nature products against antibiotic-resistant Staphylococcus aureus, persisters and biofilms 2. Chieh-Hsien Lu#, Chung-Wai Shiau#, Yung-Chi Chang, Hsiu-Ni Kung, Jui-Ching Wu, Chui-Hian Lim, Hui-Hui Yeo, Han-Chu Chang, Han-Sheng Chien, Sheng-Hsuan Huang, Wei-Kang Hung, Jun-Rong Wei, Hao-Chieh Chiu* (2021 Apr) SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance. Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkab114 (SCI) (#Equal Contribution) 3. Research Paper Award, Department of Clinical Laboratory Sciences and Medical Biotechnology, NTU, 2021. |
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Chien, Han-Sheng Master Student 2019.09 - 2020.09 |
1. Shiou-Ru Tzeng, Yi-Wei Huang, Yao-Qing Zhang, Ching-Yi Yang, Han-Sheng Chien, Yi-Ru Chen, Sung-Liang Yu, Ching S. Chen, Hao-Chieh Chiu* (2020 Dec) A Celecoxib Derivative Eradicates Antibiotic-Resistant Staphylococcus aureus and Biofilms by Targeting YidC2 Translocase. International Journal of Molecular Sciences. DOI: 10.3390/ijms21239312 (SCI) 2. Chieh-Hsien Lu, Chung-Wai Shiau, Yung-Chi Chang, Hsiu-Ni Kung, Jui-Ching Wu, Chui-Hian Lim, Hui-Hui Yeo, Han-Chu Chang, Han-Sheng Chien, Sheng-Hsuan Huang, Wei-Kang Hung, Jun-Rong Wei, Hao-Chieh Chiu* (2021 Apr) SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance. Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkab114 (SCI) |
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Wan, Tsai-Wen Postdoctoral Researcher 2020.07 - Now |
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Yeo, Hui-Hui Ph.D. student 2020.09 - Now |
1. Chieh-Hsien Lu#, Chung-Wai Shiau#, Yung-Chi Chang, Hsiu-Ni Kung, Jui-Ching Wu, Chui-Hian Lim, Hui-Hui Yeo, Han-Chu Chang, Han-Sheng Chien, Sheng-Hsuan Huang, Wei-Kang Hung, Jun-Rong Wei, Hao-Chieh Chiu* (2021 Apr) SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance. Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkab114 (SCI) (#Equal Contribution) |
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Lin, Hsueh-Chun Master student 2020.09 - Now |
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Lai, Jian-Hong Master student 2021.09 - Now |
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Chen, Ling-Han Master student 2021.09 - Now |
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