Notes:

(1) Variables in red need to be assigned based on demographic and medical data from the area of interest.

(2) Variables in blue are default values. They can be changed if more information becomes available. However, different values do not seem to affect the results much.

(3) After users assign values for variables in red, the resulting Y, F, or increased incidence will be changed. User can then create a plot for various k's and the corresponding resulting values.

(4) Reference of the calculation is Wang et al. (2006), Maximum Number of Live Births per Donor in Artificial Insemination.

----- Created by Charlotte Wang in Aug, 2006. -----

maximum number of live births per donor		average number of natural children per donor = fertility rate	average number of children per donor in one pregnancy
k

number of potential marriages between offspring and relatives ( by kinship)
half sibling	biological father or mother	uncle-nice or aunt-nephew	half uncle-nice or half aunt-nephew
first cousin	half first cousin	first cousin once removed	half first cousin once removed

the chance that a newborn will ever reproduce	the factor of assortive mating for age	the factor of assortive mating for phenotype	the factor of assortive mating for geographical location	average number of newborns in a year
l		C	Q	A

number of donors per year	success rate	number of potential marriages between offspring and relatives	probability of mating
D	S

Result 1: Number of Consanguineous Mating per Year

number of consanguineous mating per year

Result 2: Average Level of Coefficient of Inbreeding in Population with AID

the original coefficient of inbreeding existing in the population	number of marriages per year
F0	M
average level of coefficient of inbreeding in population with AID

Result 3: Average Level of Coefficient of Inbreeding in Population with AID